Zobrazeno 21 - 30
of 38
pro vyhledávání: '"Sumiti Vinayak"'
Autor:
Venkatachalam Udhayakumar, Sean M. Griffing, John W. Barnwell, Tauqeer Alam, Nancy O. Duah, Anita Ghansah, Laurence Slutsker, Sumiti Vinayak, Michael D. Wilson, Amanda Poe, Dziedzom K. de Souza, Kwadwo A. Koram, Kwame Asamoa
Publikováno v:
The Journal of Infectious Diseases. 203:220-227
Background. In 2005, Ghana adopted artemisinin-based combination therapy (ACT) for primary treatment of falciparum malaria. A comprehensive study of the drug-resistance–associated mutations and their genetic lineages will lead to a better understan
Autor:
Venkatachalam Udhayakumar, Wichai Satimai, Laurence Slutsker, Tauqeer Alam, John W. Barnwell, Kanungnit Congpuong, Chansuda Wongsrichanalai, Ananias A. Escalante, Sumiti Vinayak
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:155-164
The emergence and spread of drug-resistant Plasmodium falciparum have been a major impediment for the control of malaria worldwide. Earlier studies have shown that similar to chloroquine (CQ) resistance, high levels of pyrimethamine resistance in P.
Autor:
Sumiti Vinayak, Chansuda Wongsrichanalai, Sinuon Muth, Frederick Ariey, William O. Rogers, Tauqeer Alam, Venkatachalam Udhayakumar, Jason D. Maguire, Naman K. Shah, Thierry Fandeur, Augustina I. Susanti, Pharath Lim, Rithy Sem, John W. Barnwell, Ananias A. Escalante, Steven R. Meshnick
Publikováno v:
The Journal of Infectious Diseases. 201:1551-1560
The Thailand-Cambodia border has been an epicenter for drug-resistant malaria and is where resistance to chloroquine (CQ) emerged in the early 1960s [1]. Sulfadoxine-pyrimethamine (SP) officially became the first-line treatment for falciparum malaria
Autor:
Tonya Mixson-Hayden, Luke M Syphard, Sankar Sridaran, Sean M. Griffing, Ananias A. Escalante, Andrea M. McCollum, Venkatachalam Udhayakumar, John W. Barnwell, Sumiti Vinayak, Leopoldo Villegas
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:1572-1579
Molecular tools are valuable for determining evolutionary history and the prevalence of drug-resistant malaria parasites. These tools have helped to predict decreased sensitivity to antimalarials and fixation of multidrug resistance genotypes in some
Autor:
Chutatip Chompoonuch, Kanungnit Congpuong, Wittaya Saipomsud, Sumiti Vinayak, Wichai Satimai, Paitoon Niemhom
Publikováno v:
Asian Biomedicine. 4:289-295
Background: In Kanchanaburi province located on the Thai-Myanmar border, Plasmodium falciparum parasites have developed significant resistance to commonly-used anti-malarials. For use against falciparum malaria, 2-day artesunate-mefloquine combinatio
Autor:
Yagya D. Sharma, Sumiti Vinayak
Publikováno v:
Oligonucleotides. 17:189-200
The nonmevalonate pathway of isoprenoid biosynthesis in the apicoplast of the human malaria parasite Plasmodium falciparum is distinct from the mevalonate-dependent pathway of humans and thus a good drug target. We describe here the hammerhead ribozy
Autor:
Musharraf A. Ansari, Ashwani Kumar, Yagya D. Sharma, Neeru Singh, Vas Dev, Hina Chandawat, Pooja Mittra, Manoj K. Das, Sumiti Vinayak, Sukla Biswas
Publikováno v:
The Journal of Infectious Diseases. 193:1304-1312
Effective malaria control programs require continuous monitoring of drug pressure in the field, using molecular markers.We used sequence analysis to investigate the pfcrt and pfmdr1 mutations in Indian Plasmodium falciparum isolates. To evaluate the
Autor:
Anatoli Naumov, Elena S. Suvorova, Boris Striepen, Carrie F. Brooks, Sumiti Vinayak, Michael W. White
Publikováno v:
mBio, Vol 5, Iss 6 (2014)
mBio
mBio
Apicomplexa are obligate intracellular parasites that cause important diseases in humans and animals. Manipulating the pathogen genome is the most direct way to understand the functions of specific genes in parasite development and pathogenesis. In T
Autor:
Praveen K. Bharti, Vidhan Jain, Yagya D. Sharma, Vanshika Lumb, Vandana Choudhary, Mohammad Tauqeer Alam, Neeru Singh, Sumiti Vinayak, Mohammad Zeeshan, Puspendra P. Singh, Mohd. Shoeb Alam, Rupesh K. Tyagi, Venkatachalam Udhayakumar, Hema Bora, Pooja Mittra
Publikováno v:
PLoS One, 7
PLoS ONE
PLoS One, 7, 8
PLoS ONE, Vol 7, Iss 8, p e43430 (2012)
PLoS ONE
PLoS One, 7, 8
PLoS ONE, Vol 7, Iss 8, p e43430 (2012)
Contains fulltext : 108006.pdf (Publisher’s version ) (Open Access) RTS,S is the most advanced malaria vaccine candidate, currently under phase-III clinical trials in Africa. This Plasmodium falciparum vaccine contains part of the central repeat re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29a583677562fb7310ba7bd15743c13
http://hdl.handle.net/2066/108006
http://hdl.handle.net/2066/108006
Autor:
Sinuon Muth, Tonya Mixson-Hayden, Chansuda Wongsrichanalai, Andrea M. McCollum, Tauqeer Alam, John W. Barnwell, Rithy Sem, Sumiti Vinayak, Frederick Ariey, Venkatachalam Udhayakumar, Steven R. Meshnick, Thierry Fandeur, Ananias A. Escalante, William O. Rogers, Naman K. Shah, Pharath Lim
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 6, Iss 3, p e1000830 (2010)
PLoS Pathogens, Vol 6, Iss 3, p e1000830 (2010)
The Thailand-Cambodia border is the epicenter for drug-resistant falciparum malaria. Previous studies have shown that chloroquine (CQ) and pyrimethamine resistance originated in this region and eventually spread to other Asian countries and Africa. H