Zobrazeno 11 - 20
of 392
pro vyhledávání: '"Steven G. DuBois"'
Autor:
Stefan K. Zöllner, James F. Amatruda, Sebastian Bauer, Stéphane Collaud, Enrique de Álava, Steven G. DuBois, Jendrik Hardes, Wolfgang Hartmann, Heinrich Kovar, Markus Metzler, David S. Shulman, Arne Streitbürger, Beate Timmermann, Jeffrey A. Toretsky, Yasmin Uhlenbruch, Volker Vieth, Thomas G. P. Grünewald, Uta Dirksen
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 8, p 1685 (2021)
Ewing sarcoma, a highly aggressive bone and soft-tissue cancer, is considered a prime example of the paradigms of a translocation-positive sarcoma: a genetically rather simple disease with a specific and neomorphic-potential therapeutic target, whose
Externí odkaz:
https://doaj.org/article/bbbd216a76ac42f09ce89d979a50c221
Publikováno v:
Sarcoma, Vol 2018 (2018)
Background. As of 2013, the WHO has classified peripheral primitive neuroectodermal tumors (PNETs) within the umbrella of Ewing sarcoma family of tumors (ESFTs) given their shared biology. Histologic features differ between PNET and Ewing sarcoma (ES
Externí odkaz:
https://doaj.org/article/aaa2773d6df040ed90a9534fc43022f1
Autor:
Thomas Cash, Hong Yin, Courtney McCracken, Zhi Geng, Steven G. DuBois, Bahig M. Shehata, Thomas A. Olson, Howard M. Katzenstein, Cynthia Wetmore
Publikováno v:
Sarcoma, Vol 2017 (2017)
Background. Ezrin is a membrane-cytoskeleton linker protein that has been associated with metastasis and poor outcomes in osteosarcoma and high-grade soft tissue sarcomas. The prognostic value of ezrin expression in Ewing sarcoma is unknown. Methods.
Externí odkaz:
https://doaj.org/article/d059f513979348e9b8eb959389b513c1
Clinical characteristics and outcomes of pediatric patients with desmoplastic small round cell tumor
Publikováno v:
Rare Tumors, Vol 8, Iss 1 (2016)
Desmoplastic small round cell tumor (DSRCT) is a rare malignancy that typically affects pediatric and young adult patients. There are limited data on the clinical features of pediatric DSRCT. We selected patients aged 0-21 years reported to the Surve
Externí odkaz:
https://doaj.org/article/b2d6a9aa2c124b7682aa37584ebacb6f
Publikováno v:
Sarcoma, Vol 2014 (2014)
Background. Extraskeletal osteosarcoma (ESOS) is a rare subtype of osteosarcoma. We investigated patient characteristics, overall survival, and prognostic factors in ESOS. Methods. We identified cases of high-grade osteosarcoma with known tissue of o
Externí odkaz:
https://doaj.org/article/4b9796ed5df24cd59776e29556060e55
Autor:
Samuel Abbou, Kelly Klega, Junko Tsuji, Mohammad Tanhaemami, David Hall, Donald A. Barkauskas, Mark D. Krailo, Carrie Cibulskis, Anwesha Nag, Aaron R. Thorner, Samuel Pollock, Alma Imamovic-Tuco, Jack F. Shern, Steven G. DuBois, Rajkumar Venkatramani, Douglas S. Hawkins, Brian D. Crompton
Publikováno v:
Journal of Clinical Oncology. 41:2382-2393
PURPOSE Novel biomarkers are needed to differentiate outcomes in intermediate-risk rhabdomyosarcoma (IR RMS). We sought to evaluate strategies for identifying circulating tumor DNA (ctDNA) in IR RMS and to determine whether ctDNA detection before the
Autor:
Steven G. DuBois, Mark D. Krailo, Julia Glade-Bender, Allen Buxton, Nadia Laack, R. Lor Randall, Helen X. Chen, Nita L. Seibel, Matthew Boron, Stephanie Terezakis, Christine Hill-Kayser, Andrea Hayes, Joel M. Reid, Lisa Teot, Dinesh Rakheja, Richard Womer, Carola Arndt, Stephen L. Lessnick, Brian D. Crompton, E. Anders Kolb, Heike Daldrup-Link, Eric Eutsler, Damon R. Reed, Katherine A. Janeway, Richard G. Gorlick
Publikováno v:
Journal of Clinical Oncology. 41:2098-2107
PURPOSE Monoclonal antibodies directed against insulin-like growth factor-1 receptor (IGF-1R) have shown activity in patients with relapsed Ewing sarcoma. The primary objective of Children's Oncology Group trial AEWS1221 was to determine if the addit
Autor:
Kevin Campbell, Susan Groshen, Angela C. Evans, Stephen Wilson, Aimy Sebastian, Gabriela G. Loots, Araz Marachelian, Myriam Armant, Sharmistha Pal, Daphne A. Haas-Kogan, Julie R. Park, Meaghan Granger, Katherine K. Matthay, Matthew A. Coleman, Steven G. DuBois
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:1115-1128
Autor:
Lucas Moreno, Steven G. DuBois, Julia Glade Bender, Audrey Mauguen, Nick Bird, Vickie Buenger, Michela Casanova, François Doz, Elizabeth Fox, Lia Gore, Douglas S. Hawkins, Shai Izraeli, David T.W. Jones, Pamela R. Kearns, Jan J. Molenaar, Karsten Nysom, Stefan Pfister, Gregory Reaman, Malcolm Smith, Brenda Weigel, Gilles Vassal, Christian Michel Zwaan, Xavier Paoletti, Alexia Iasonos, Andrew D.J. Pearson
Publikováno v:
Scientia
PURPOSE There is an increasing need to evaluate innovative drugs for childhood cancer using combination strategies. Strong biological rationale and clinical experience suggest that multiple agents will be more efficacious than monotherapy for most di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42cfed0b001a0a7bb4dbc82e8b4ec2a0
https://hdl.handle.net/11351/9922
https://hdl.handle.net/11351/9922
Autor:
Pooja Hingorani, Mark Krailo, Allen Buxton, Paul Hutson, Paul M. Sondel, Mitchell Diccianni, Alice Yu, Carol D. Morris, Richard B. Womer, Brian Crompton, R Lor Randall, Lisa A. Teot, Steven G. DuBois, Katherine A. Janeway, Richard G. Gorlick, Michael S. Isakoff
Publikováno v:
European Journal of Cancer. 172:264-275
Novel effective therapies are urgently needed in recurrent osteosarcoma. GD2 is expressed in human osteosarcoma tumours and cell lines. This study evaluated the disease control rate (DCR) in patients with recurrent osteosarcoma treated with the anti-