Zobrazeno 61 - 70
of 143
pro vyhledávání: '"Stephen H. Bryant"'
Publikováno v:
Proteins: Structure, Function, and Genetics. 28:494-514
A survey was compiled of several characteristics of the intersubunit contacts in 58 oligomeric proteins, and of the intermolecular contracts in the lattice for 223 protein crystal structures. The total number of atoms in contact and the secondary str
Autor:
Stephen H. Bryant, Aron Marchler-Bauer
Publikováno v:
Trends in Biochemical Sciences. 22:236-240
Prediction of protein structure by fold recognition, or threading, was recently put to the test in a ‘blind’ structure prediction experiment, CASP2. Thirty-two teams from around the world participated, preparing predictions for 22 different ‘ta
Autor:
Stephen H. Bryant, Aron Marchler-Bauer
Publikováno v:
Proteins: Structure, Function, and Genetics. 29:74-82
Threading predictions for CASP2 target proteins were compared to their true structures using a series of precisely defined measures of agreement, calculated in a fully automatic way. Fold recognition specificity was calculated as the proportion of a
Publikováno v:
Journal of Cheminformatics
PubChem is an open repository for molecular structures, their properties and biological activities [1]. The number of deposited structures has been steadily increasing since its creation in 2004. Today, it contains more than 92 million substances (Pu
Publikováno v:
Journal of Cheminformatics, Vol 5, Iss 1, p 1 (2013)
Journal of Cheminformatics
Journal of Cheminformatics
Background PubChem is a free and publicly available resource containing substance descriptions and their associated biological activity information. PubChem3D is an extension to PubChem containing computationally-derived three-dimensional (3-D) struc
Autor:
Stephen H. Bryant
Publikováno v:
Proteins: Structure, Function, and Genetics. 26:172-185
Threading experiments with proteins from the globin family provide an indication of the nature of the structural similarity required for successful fold recognition and accurate sequence-structure alignment. Threading scores are found to rise above t
Publikováno v:
Trends in Biochemical Sciences. 21:226-229
Autor:
Stephen F. Altschul, Stephen H. Bryant
Publikováno v:
Current Opinion in Structural Biology. 5:236-244
The past two years have seen the rapid development of new recognition methods for protein structure prediction. These algorithms ‘thread’ the sequence of one protein through the known structure of another, looking for an alignment that correspond
Publikováno v:
Journal of Cheminformatics
Journal of Cheminformatics, Vol 4, Iss 1, p 28 (2012)
Journal of Cheminformatics, Vol 4, Iss 1, p 28 (2012)
Background To improve the utility of PubChem, a public repository containing biological activities of small molecules, the PubChem3D project adds computationally-derived three-dimensional (3-D) descriptions to the small-molecule records contained in
Autor:
Viswanadham Sridhara, Stephen H. Bryant, An Chi, Dina L. Bai, Jeffrey Shabanowitz, Donald F. Hunt, Lewis Y. Geer
Publikováno v:
Proteome Science
Proteome Science, Vol 10, Iss 1, p 8 (2012)
Proteome Science, Vol 10, Iss 1, p 8 (2012)
Background Electron Transfer Dissociation [ETD] can dissociate multiply charged precursor polypeptides, providing extensive peptide backbone cleavage. ETD spectra contain charge reduced precursor peaks, usually of high intensity, and whose pattern is