Zobrazeno 11 - 20
of 752
pro vyhledávání: '"Stephen A Murray"'
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-18 (2022)
Abstract Complex morphological traits are the product of many genes with transient or lasting developmental effects that interact in anatomical context. Mouse models are a key resource for disentangling such effects, because they offer myriad tools f
Externí odkaz:
https://doaj.org/article/7defe75069d24f29bca1c5a94da00059
Autor:
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir D. Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
Publikováno v:
Scientific Data, Vol 10, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/be08db417e494e3e9e3dd747d51524cb
Autor:
Kelsey H. Elliott, Sai K. Balchand, Christian Louis Bonatto Paese, Ching-Fang Chang, Yanfen Yang, Kari M. Brown, Daniel T. Rasicci, Hao He, Konrad Thorner, Praneet Chaturvedi, Stephen A. Murray, Jing Chen, Aleksey Porollo, Kevin A. Peterson, Samantha A. Brugmann
Publikováno v:
Development. 150
Primary cilia are nearly ubiquitous organelles that transduce molecular and mechanical signals. Although the basic structure of the cilium and the cadre of genes that contribute to ciliary formation and function (the ciliome) are believed to be evolu
Autor:
Chengxiang Qiu, Beth K. Martin, Ian C. Welsh, Riza M. Daza, Truc-Mai Le, Xingfan Huang, Eva K. Nichols, Megan L. Taylor, Olivia Fulton, Diana R. O’Day, Anne Roshella Gomes, Saskia Ilcisin, Sanjay Srivatsan, Xinxian Deng, Christine M. Disteche, William Stafford Noble, Nobuhiko Hamazaki, Cecilia B. Moens, David Kimelman, Junyue Cao, Alexander F. Schier, Malte Spielmann, Stephen A. Murray, Cole Trapnell, Jay Shendure
The house mouse,Mus musculus, is an exceptional model system, combining genetic tractability with close homology to human biology. Gestation in mouse development lasts just under three weeks, a period during which its genome orchestrates the astonish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6adc05866263a01873e739f8b89c8a3e
https://doi.org/10.1101/2023.04.05.535726
https://doi.org/10.1101/2023.04.05.535726
Autor:
Chengxiang Qiu, Junyue Cao, Beth K. Martin, Tony Li, Ian C. Welsh, Sanjay Srivatsan, Xingfan Huang, Diego Calderon, William Stafford Noble, Christine M. Disteche, Stephen A. Murray, Malte Spielmann, Cecilia B. Moens, Cole Trapnell, Jay Shendure
Publikováno v:
Nature Genetics. 54:328-341
Mammalian embryogenesis is characterized by rapid cellular proliferation and diversification. Within a few weeks, a single-cell zygote gives rise to millions of cells expressing a panoply of molecular programs. Although intensively studied, a compreh
Autor:
Lu Wang, Caleb Heffner, Keng loi Vong, Chelsea Barrows, Yoo-Jin Ha, Sangmoon Lee, Pablo Lara-Gonzalez, Ishani Jhamb, Dennis Van Der Meer, Robert Loughnan, Nadine Parker, David Sievert, Swapnil Mittal, Mahmoud Y. Issa, Ole A. Andreassen, Anders Dale, William B. Dobyns, Maha S. Zaki, Stephen A. Murray, Joseph G. Gleeson
Publikováno v:
Proceedings of the National Academy of Sciences. 120
TMEM161B encodes an evolutionarily conserved widely expressed novel 8-pass transmembrane protein of unknown function in human. Here we identify TMEM161B homozygous hypomorphic missense variants in our recessive polymicrogyria (PMG) cohort. Patients c
Autor:
Stephen C. Murray
Publikováno v:
The Journal of Pacific History. 58:206-208
Autor:
Sara Wells, Marc Parisien, Abigail J. D’Souza, Rasneer Sonia Bains, Hamed Haselimashhadi, Mary E. Dickinson, Matthew Mckay, Amelia M. Willett, Christopher S. Ward, Robert Braun, Jeremy Mason, Stephen A. Murray, Emma Peterson, Michayla A. Moore, Damian Smedley, Erin E. Young, Luis Santos, Elissa L. Chesler, Laura C. Anderson, Rachel Urban, Helen Parkinson, Lynette Bower, John R. Seavitt, Dawei Qu, Leslie O. Goodwin, Vivek Kumar, Jason D. Heaney, Subhiksha Srinivasan, Kevin C K Lloyd, Mark E. Harrison, Steve D.M. Brown, Colin McKerlie, Ann M. Flenniken, Jacqueline K. White, Lauryl M. J. Nutter, Ziyue Huang, Jason A. Bubier, Daniel J. Delbarre, Robert P. Bonin, Kyle M. Baumbauer, Alexandr Bezginov, Dave Clary, Igor Vukobradovic, Ann-Marie Mallon, Silvia Mandillo, Luda Diatchenko, Surabi Veeraragavan, Michelle Stewart, Rodney C. Samaco, Janine M Wotton
Publikováno v:
Pain (Amst. Print) (2021). doi:10.1097/j.pain.0000000000002481
info:cnr-pdr/source/autori:Wotton, Janine M.a; Peterson, Emmaa; Flenniken, Ann M.b,c; Bains, Rasneer S.d; Veeraragavan, Surabie,f; Bower, Lynette R.g; Bubier, Jason A.a; Parisien, March; Bezginov, Alexandrb,i; Haselimashhadi, Hamedj; Mason, Jeremyj; Moore, Michayla A.a; Stewart, Michelle E.d; Clary, Dave A.g; Delbarre, Daniel J.k; Anderson, Laura C.a; D'Souza, Abigailb,c; Goodwin, Leslie O.a; Harrison, Mark E.d; Huang, Ziyueb,c; Mckay, Matthewa; Qu, Daweib,c; Santos, Luisk; Srinivasan, Subhikshae; Urban, Rachela; Vukobradovic, Igorb,c; Ward, Christopher S.l; Willett, Amelia M.a; Braun, Robert E.a; Brown, Steve D.M.k; Dickinson, Mary E.l; Heaney, Jason D.e; Kumar, Viveka; Lloyd, K.C. Kentg,m; Mallon, Ann-Mariek; McKerlie, Colinc,i; Murray, Stephen A.a; Nutter, Lauryl M.J.b,i; Parkinson, Helenj; Seavitt, John R.e; Wells, Sarad; Samaco, Rodney C.e,f; Chesler, Elissa J.a; Smedley, Damiann; Diatchenko, Ludah; Baumbauer, Kyle M.o; Young, Erin E.p; Bonin, Robert P.q; Mandillo, Silviar; White, Jacqueline K.a,* The International Mouse Phenotyping Consortium/titolo:Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen/doi:10.1097%2Fj.pain.0000000000002481/rivista:Pain (Amst. Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Wotton, Janine M.a; Peterson, Emmaa; Flenniken, Ann M.b,c; Bains, Rasneer S.d; Veeraragavan, Surabie,f; Bower, Lynette R.g; Bubier, Jason A.a; Parisien, March; Bezginov, Alexandrb,i; Haselimashhadi, Hamedj; Mason, Jeremyj; Moore, Michayla A.a; Stewart, Michelle E.d; Clary, Dave A.g; Delbarre, Daniel J.k; Anderson, Laura C.a; D'Souza, Abigailb,c; Goodwin, Leslie O.a; Harrison, Mark E.d; Huang, Ziyueb,c; Mckay, Matthewa; Qu, Daweib,c; Santos, Luisk; Srinivasan, Subhikshae; Urban, Rachela; Vukobradovic, Igorb,c; Ward, Christopher S.l; Willett, Amelia M.a; Braun, Robert E.a; Brown, Steve D.M.k; Dickinson, Mary E.l; Heaney, Jason D.e; Kumar, Viveka; Lloyd, K.C. Kentg,m; Mallon, Ann-Mariek; McKerlie, Colinc,i; Murray, Stephen A.a; Nutter, Lauryl M.J.b,i; Parkinson, Helenj; Seavitt, John R.e; Wells, Sarad; Samaco, Rodney C.e,f; Chesler, Elissa J.a; Smedley, Damiann; Diatchenko, Ludah; Baumbauer, Kyle M.o; Young, Erin E.p; Bonin, Robert P.q; Mandillo, Silviar; White, Jacqueline K.a,* The International Mouse Phenotyping Consortium/titolo:Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen/doi:10.1097%2Fj.pain.0000000000002481/rivista:Pain (Amst. Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume
Identifying the genetic determinants of pain is a scientific imperative given the magnitude of the global health burden that pain causes. Here, we report a genetic screen for nociception, performed under the auspices of the International Mouse Phenot
Autor:
Stephen A. Murray, Martin Ringwald, Hiroaki Onda, Michelle N. Perry, Cynthia L. Smith, Constance M. Smith
Publikováno v:
Mammalian Genome. 33:55-65
Recombinase alleles and transgenes can be used to facilitate spatio-temporal specificity of gene disruption or transgene expression. However, the versatility of this in vivo recombination system relies on having detailed and accurate characterization
Autor:
Jeanette M. Metzger, Yuyuan Wang, Samuel S. Neuman, Kathy J. Snow, Stephen A. Murray, Cathleen M. Lutz, Viktoriya Bondarenko, Jesi Felton, Kirstan Gimse, Ruosen Xie, Yi Zhao, Matthew T. Flowers, Heather A. Simmons, Subhojit Roy, Krishanu Saha, Jon Levine, Marina E. Emborg, Shaoqin Gong
Genome editing of somatic cells via clustered regularly interspaced short palindromic repeats (CRISPR) offers promise for new therapeutics to treat a variety of genetic disorders, including neurological diseases. However, the dense and complex parenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3377092d36e7a30c1410b12546007251
https://doi.org/10.1101/2022.07.24.501299
https://doi.org/10.1101/2022.07.24.501299