Zobrazeno 11 - 20
of 44
pro vyhledávání: '"Stefania Senger"'
Autor:
Bobby J. Cherayil, Smriti Verma, Rachel A Prescott, Alessio Fasano, Christina S. Faherty, Laura A. MacKenzie Ingano, Emily Hill, Kourtney P. Nickerson, Stefania Senger
Publikováno v:
Gut Microbes
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Gut Microbes, Vol 11, Iss 3, Pp 526-538 (2020)
Salmonella enterica serovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by S. Typhi. We examin
Autor:
Laura A. MacKenzie Ingano, Alba Miranda-Ribera, Rosiane Lima, Meryl Perlman, Alejandro Llanos-Chea, Alessio Fasano, Gloria Serena, Christina S. Faherty, Marcelo B. Sztein, Stefania Senger, Kourtney P. Nickerson
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 1 (2021)
Microbiology Spectrum
Microbiology Spectrum
Gastrointestinal infections cause significant morbidity and mortality worldwide. The complexity of human biology and limited insights into host-specific infection mechanisms are key barriers to current therapeutic development. Here, we demonstrate th
Autor:
Anna Sapone, Laura A. MacKenzie Ingano, Rachel Freire, Stefania Senger, Ruslan I. Sadreyev, Alessio Fasano, Gloria Serena, Anthony Anselmo, Murat Cetinbas
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Celiac disease (CD) is an immune-mediated disorder triggered by gluten exposure. The contribution of the adaptive immune response to CD pathogenesis has been extensively studied, but the absence of valid experimental models has hampered our understan
Autor:
Stefania Senger, Laura A. MacKenzie Ingano, Kourtney P. Nickerson, Gloria Serena, Timothy K. Lu, Alejandro Llanos-Chea, Robert J. Citorik, Alessio Fasano, Christina S. Faherty
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 68:509-516
Objective Enteric bacterial pathogens cause diarrheal disease and mortality at significant rates throughout the world, particularly in children younger than 5 years. Our ability to combat bacterial pathogens has been hindered by antibiotic resistance
Autor:
Taylor Broda, Alexandra Calor, Xiaowen Cheng, Mahmoud I. Elbadry, Ahmed El-Hashash, Adegbenro Omotuyi John Fakoya, Deming Jiang, Magdalena Kasendra, Jingwen Liu, Mahmoud Shaaban Mohamed, Cynthia Oghenekome Okaruefe, Adekunle Ebenezer Omole, Nihal Satyadev, Stefania Senger, Mirjam van Weissenbruch, Yiyi Yang, Chao-Ling Yao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3506a1d0030caa517b1c72740165be5
https://doi.org/10.1016/b978-0-12-821269-1.00016-3
https://doi.org/10.1016/b978-0-12-821269-1.00016-3
In this chapter, we have compiled a selection of exemplary studies to provide the reader with insights on the current use of human-derived organoids in the biomedical field and their perspective application as more is learned about them. Organoids de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80c23826f14ea9a1c0cb6bf8300f33d
https://doi.org/10.1016/b978-0-12-821269-1.00010-2
https://doi.org/10.1016/b978-0-12-821269-1.00010-2
Publikováno v:
Microorganisms
Microorganisms, Vol 8, Iss 504, p 504 (2020)
Microorganisms, Vol 8, Iss 504, p 504 (2020)
The molecular complexity of host-pathogen interactions remains poorly understood in many infectious diseases, particularly in humans due to the limited availability of reliable and specific experimental models. To bridge the gap between classical two
Autor:
Kourtney P. Nickerson, Marcelo B. Sztein, Deepak Kumar, Renata C. Lima, Claire M. Fraser, Y. Zhang, Stefania Senger, Maria Fiorentino, Laura A. MacKenzie Ingano, William A. Flavahan, Alessio Fasano, Christina S. Faherty, S. Patel
Publikováno v:
EBioMedicine
EBioMedicine, Vol 31, Iss, Pp 92-109 (2018)
EBioMedicine, Vol 31, Iss, Pp 92-109 (2018)
Commensal microorganisms influence a variety of host functions in the gut, including immune response, glucose homeostasis, metabolic pathways and oxidative stress, among others. This study describes how Salmonella Typhi, the pathogen responsible for
Autor:
Ruslan I. Sadreyev, William Allan Walker, Weishu Zhu, Laura A. MacKenzie Ingano, Antony Anselmo, Stefania Senger, Alessio Fasano, Rachel Freire
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 549-568 (2018)
Background & Aims: Untreated necrotizing enterocolitis (NEC) can lead to massive inflammation resulting in intestinal necrosis with a high mortality rate in preterm infants. Limited access to human samples and relevant experimental models have hamper
Autor:
Leslie Cope, Linda M.S. Resar, Wenyong Kuang, Lingling Xian, David L. Huso, Andrew J. Ewald, Stefania Senger, Amy Belton, Tait Huso, Alessio Fasano, Dan Georgess, Yu Ting Chang, Xiaoyan Zhang, Qihua Gu
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
High-mobility group A1 (Hmga1) chromatin remodelling proteins are enriched in intestinal stem cells (ISCs), although their function in this setting was unknown. Prior studies showed that Hmga1 drives hyperproliferation, aberrant crypt formation and p