Zobrazeno 11 - 20
of 81
pro vyhledávání: '"Sigurdis Haraldsdottir"'
Autor:
Kristen K. Ciombor, Yoanna Pumpalova, Christina Wu, Tanios Bekaii-Saab, Mohamad Bassam Sonbol, Jordan Berlin, Gregory B. Lesinski, Zhengjia Chen, Bassel F. El-Rayes, Ibrahim Halil Sahin, Amber Draper, Subir Goyal, Sigurdis Haraldsdottir, Satya Das, Daniel H. Ahn
Publikováno v:
Oncologist
Background Immune checkpoint inhibitor (ICI) therapy is highly effective in metastatic mismatch repair-deficient (MMR-D) colorectal cancer (CRC). In this study, we evaluated molecular and clinical predictors of ICI response in MMR-D CRC. Materials an
Autor:
Sigurdis Haraldsdottir
Publikováno v:
JCO precision oncology. 1
Autor:
Yu Shyr, Kristen K. Ciombor, Gino Pineda, Yoanna Pumpalova, Chih-Yuan Hsu, Dana Backlund Cardin, Mehmet Asim Bilen, Laura W. Goff, Jordan Berlin, Ibrahim Halil Sahin, Shih Kai Chu, Christina Wu, Emily Pei Ying Lin, Satya Das, George A. Fisher, Sigurdis Haraldsdottir
Publikováno v:
Oncologist
Introduction Immune-related adverse event (IRAE) onset may represent a clinical biomarker for anti-programmed cell death protein 1 (PD-1) antibody response based on emerging evidence from patients with various advanced malignancies. This phenomenon h
Autor:
Michael J. Hall, Scott E. Regenbogen, June Mikkelson, Robert J. Mayer, Dennis J. Ahnen, Patrick M. Lynch, Audrey J. Lazenby, William Grady, Sigurdis Haraldsdottir, Mary A. Dwyer, Reid M. Ness, Daniel C. Chung, Priyanka Kanth, Samir Gupta, Ndiya Ogba, Shajan Peter, Jason B. Klapman, Lee-may Chen, Arnold J. Markowitz, Francis M. Giardiello, Stanley R. Hamilton, Gregory S. Cooper, Xavier Llor, Amy L. Halverson, Heather Hampel, Jennifer M. Weiss, Dayna S. Early, Dawn Provenzale, Thomas P. Slavin
Publikováno v:
Journal of the National Comprehensive Cancer Network. 17:1032-1041
Identifying individuals with hereditary syndromes allows for improved cancer surveillance, risk reduction, and optimized management. Establishing criteria for assessment allows for the identification of individuals who are carriers of pathogenic gene
Autor:
Elizabeth K Bancroft, Elizabeth C Page, Mark N Brook, Sarah Thomas, Natalie Taylor, Jennifer Pope, Jana McHugh, Ann-Britt Jones, Questa Karlsson, Susan Merson, Kai Ren Ong, Jonathan Hoffman, Camilla Huber, Lovise Maehle, Eli Marie Grindedal, Astrid Stormorken, D Gareth Evans, Jeanette Rothwell, Fiona Lalloo, Angela F Brady, Marion Bartlett, Katie Snape, Helen Hanson, Paul James, Joanne McKinley, Lyon Mascarenhas, Sapna Syngal, Chinedu Ukaegbu, Lucy Side, Tessy Thomas, Julian Barwell, Manuel R Teixeira, Louise Izatt, Mohnish Suri, Finlay A Macrae, Nicola Poplawski, Rakefet Chen-Shtoyerman, Munaza Ahmed, Hannah Musgrave, Nicola Nicolai, Lynn Greenhalgh, Carole Brewer, Nicholas Pachter, Allan D Spigelman, Ashraf Azzabi, Brian T Helfand, Dorothy Halliday, Saundra Buys, Teresa Ramon y Cajal, Alan Donaldson, Kathleen A Cooney, Marion Harris, John McGrath, Rosemarie Davidson, Amy Taylor, Peter Cooke, Kathryn Myhill, Matthew Hogben, Neil K Aaronson, Audrey Ardern-Jones, Chris H Bangma, Elena Castro, David Dearnaley, Alexander Dias, Tim Dudderidge, Diana M Eccles, Kate Green, Jorunn Eyfjord, Alison Falconer, Christopher S Foster, Henrik Gronberg, Freddie C Hamdy, Oskar Johannsson, Vincent Khoo, Hans Lilja, Geoffrey J Lindeman, Jan Lubinski, Karol Axcrona, Christos Mikropoulos, Anita V Mitra, Clare Moynihan, Holly Ni Raghallaigh, Gad Rennert, Rebecca Collier, Judith Offman, Zsofia Kote-Jarai, Rosalind A Eeles, Lisa Adams, Julian Adlard, Rosa Alfonso, Saira Ali, Angela Andrew, Luís Araújo, Nazya Azam, Darran Ball, Queenstone Barker, Alon Basevitch, Barbara Benton, Cheryl Berlin, Nicola Bermingham, Leah Biller, Angela Bloss, Matilda Bradford, Nicola Bradshaw, Amy Branson, Charles Brendler, Maria Brennan, Barbara Bulman, Lucy Burgess, Declan Cahill, Alice Callard, Nuria Calvo Verges, Marta Cardoso, Vanda Carter, Mario Catanzaro, Anthony Chamberlain, Cyril Chapman, Michael Chong, Caroline Clark, Virginia Clowes, Lyn Cogley, Trevor Cole, Cecilia Compton, Tom Conner, Sandra Cookson, Philip Cornford, Philandra Costello, Laura Coulier, Michaela Davies, Christopher Dechet, Bianca DeSouza, Gemma Devlin, Fiona Douglas, Emma Douglas, Darshna Dudakia, Alexis Duncan, Natalie Ellery, Sarah Everest, Sue Freemantle, Mark Frydenberg, Debbie Fuller, Camila Gabriel, Madeline Gale, Lynda Garcia, Simona Gay, Elena Genova, Angela George, Demetra Georgiou, Alexandra Gisbert, Margaret Gleeson, Wayne Glover, Vincent Gnanapragasam, Sally Goff, David Goldgar, Nuno Gonçalves, Selina Goodman, Jennifer Gorrie, Hannah Gott, Anna Grant, Catherine Gray, Julie Griffiths, Karin Gupwell, Jana Gurasashvili, Eldbjørg Hanslien, Sigurdis Haraldsdottir, Rachel Hart, Catherine Hartigan, Lara Hawkes, Tricia Heaton, Alex Henderson, Rui Henrique, Kathrine Hilario, Kathryn Hill, Peter Hulick, Clare Hunt, Melanie Hutchings, Rita Ibitoye, Thomas Inglehearn, Joanna Ireland, Farah Islam, Siti Ismail, Chris Jacobs, Denzil James, Sharon Jenkins, Irene Jobson, Anne Johnstone, Oliver Jones, Sagi Josefsberg Ben-Yehoshua, Beckie Kaemba, Karen Kaul, Zoe Kemp, Netty Kinsella, Margaret Klehm, Roger Kockelbergh, Kelly Kohut, Monika Kosicka-Slawinska, Anjana Kulkarni, Pardeep Kumar, Jimmy Lam, Mandy LeButt, Dan Leibovici, Ramona Lim, Lauren Limb, Claire Lomas, Mark Longmuir, Consol López, Tiziana Magnani, Sofia Maia, Jessica Maiden, Alison Male, Merrie Manalo, Phoebe Martin, Donna McBride, Michael McGuire, Romayne McMahon, Claire McNally, Terri McVeigh, Ehud Melzer, Mark Mencias, Catherine Mercer, Gillian Mitchell, Josefina Mora, Catherine Morton, Cathryn Moss, Morgan Murphy, Declan Murphy, Shumi Mzazi, Maria Nadolski, Anna Newlin, Pedro Nogueira, Rachael O'Keefe, Karen O'Toole, Shona O'Connell, Chris Ogden, Linda Okoth, Jorge Oliveira, Edgar Paez, Joan Palou, Linda Park, Nafisa Patel, João Paulo Souto, Allison Pearce, Ana Peixoto, Kimberley Perez, Lara Petelin, Gabriella Pichert, Charlotte Poile, Alison Potter, Nadia Preitner, Helen Purnell, Ellen Quinn, Paolo Radice, Brigette Rankin, Katie Rees, Caroline Renton, Kate Richardson, Peter Risby, Jason Rogers, Maggie Ruderman, April Ruiz, Anaar Sajoo, Natale Salvatore, Victoria Sands, Francesco Sanguedolce, Ayisha Sattar, Kathryn Saunders, Lyn Schofield, Rodney Scott, Anne Searle, Ravinder Sehra, Christina Selkirk, Kylie Shackleton, Sue Shanley, Adam Shaw, Daniel Shevrin, Hannah Shipman, Zahirah Sidat, Kas Siguake, Kate Simon, Courtney Smyth, Lesley Snadden, Nita Solanky, Joyce Solomons, Margherita Sorrentino, Barbara Stayner, Robert Stephenson, Elena Stoffel, Maggie Thomas, Alan Thompson, Lizzie Tidey, Marc Tischkowitz, Audrey Torokwa, Sharron Townshend, Katy Treherne, Karen Tricker, Quoc-Dien Trinh, Vishakha Tripathi, Clare Turnbull, Riccardo Valdagni, Nicholas Van As, Vickie Venne, Lizzie Verdon, Marco Vitellaro, Kristen Vogel, Lisa Walker, Amy Watford, Cathy Watt, Ilana Weintroub, Shelly Weiss, Scott Weissman, Michelle Weston, Jennifer Wiggins, Gillian Wise, Christopher Woodhouse, Pembe Yesildag, Alice Youngs, Matthew Yurgelun, Fabiana Zollo
Publikováno v:
Bancroft, EK, Page, EC, Brook, MN, Thomas, S, Taylor, N, Pope, J, McHugh, J, Jones, AB, Karlsson, Q, Merson, S, Ong, KR, Hoffman, J, Huber, C, Maehle, L, Eeles, RA & Evans, D G 2021, ' A prospective prostate cancer screening programme for men with pathogenic variants in mismatch repair genes (IMPACT): initial results from an international prospective study. ', The Lancet. Oncology, vol. 22, no. 11, pp. 1618-1631 . https://doi.org/10.1016/S1470-2045(21)00522-2
The Lancet. Oncology, 22(11), 1618-1631. Lancet Publishing Group
LANCET ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Lancet. Oncology
The Lancet. Oncology, 22(11), 1618-1631. Lancet Publishing Group
LANCET ONCOLOGY
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
The Lancet. Oncology
Funder: Victorian Cancer Agency
Funder: NIHR Manchester Biomedical Research Centre
Funder: Cancer Research UK
Funder: Cancer Council Tasmania
Funder: Instituto de Salud Carlos III
Funder: Cancer Australia
Funder: NIHR Ox
Funder: NIHR Manchester Biomedical Research Centre
Funder: Cancer Research UK
Funder: Cancer Council Tasmania
Funder: Instituto de Salud Carlos III
Funder: Cancer Australia
Funder: NIHR Ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47cfb04c18b3df43fe6648bcca6209b5
https://doi.org/10.1016/S1470-2045(21)00522-2
https://doi.org/10.1016/S1470-2045(21)00522-2
Autor:
Sukhmani K. Padda, Touran Fardeen, George A. Fisher, Tyler Johnson, Gilbert Chu, Bianca Bruzzone, Brianna Velazquez, Gregory M. Heestand, Olga Generalova, Sigurdis Haraldsdottir, Sandy Srinivas, Kristen M. Cunanan, Mohana Roy, Robert W. Hsieh, Joel W. Neal, Heather A. Wakelee, Sumit A. Shah, Evan T. Hall, Anna Cabot, Kavitha Ramchandran, Alice C. Fan
Publikováno v:
Journal of Patient-Reported Outcomes
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)
Journal of Patient-Reported Outcomes, Vol 5, Iss 1, Pp 1-11 (2021)
Background Patient reported outcomes (PROs) have been associated with improved symptom management and quality of life in patients with cancer. However, the implementation of PROs in an academic clinical practice has not been thoroughly described. Her
Autor:
Yoanna Pumpalova, Sigurdis Haraldsdottir, Margaret M. Kozak, Daniel T. Chang, George A. Fisher, Rie von Eyben, Pamela L. Kunz
Publikováno v:
Journal of Gastrointestinal Oncology. 10:605-615
Background: Capecitabine (Cap) is an established treatment alternative to 5-fluorouracil (5-FU) for chemoradiation in rectal cancer. Few studies have compared the two agents in anal cancer. We compared outcomes and toxicities using Cap versus 5-FU in
Autor:
Diego A.S. Toesca, Jeremy P. Harris, Daniel T. Chang, Chiaojung Jillian Tsai, Julie L. Koenig, Sigurdis Haraldsdottir, Erqi L. Pollom, Albert Lin
Publikováno v:
American Journal of Clinical Oncology. 42:573-580
Randomized control trials and population-based studies do not demonstrate a definitive benefit for adjuvant chemotherapy (ACT) in stage II colon cancer (CC). Tumor sidedness and microsatellite instability (MSI) status may predict response to ACT, but
Autor:
Rachel Pearlman, Sandya Liyanarachchi, Heather Hampel, Albert de la Chapelle, Wendy L. Frankel, Sigurdis Haraldsdottir, Colin C. Pritchard, Kari Stefansson, Thorunn Rafnar, Jon G. Jonasson
Publikováno v:
Journal of Medical Genetics. 56:462-470
BackgroundPatients with colorectal cancer (CRC) with mismatch repair-deficient (dMMR) tumours without MLH1 methylation or germline MMR pathogenic variants (PV) were previously thought to have Lynch syndrome (LS). It is now appreciated that they can h
Autor:
Jennifer Thurmond, Manisha H. Shah, Vanda M. Stepanek, Mitch A. Phelps, Ming Poi, Jennifer Sexton, Lai Wei, Larry J. Schaaf, Sigurdis Haraldsdottir, Filip Janku, Erin M. Bertino, Amir Mortazavi, Vivianne Velez-Bravo, Cynthia Timmers, Kari Kendra, Vivek Subbiah, Susan Geyer
Publikováno v:
JCO Precision Oncology. :1-19
Purpose Several tumor types carry BRAF mutations and vascular endothelial growth factor pathway upregulation. Resistance mechanisms to BRAF inhibitors can include platelet-derived growth factor-β upregulation. Dabrafenib, a BRAF inhibitor, and pazop