Zobrazeno 41 - 50
of 145
pro vyhledávání: '"Sharon Gardner"'
Autor:
Laura Vasquez, C Altshuler, Sharon Gardner, Joseph Stanek, Girish Dhall, Jonathan L. Finlay, Kelley Haley
Publikováno v:
Bone Marrow Transplantation. 51:945-948
Since 1991, three sequential prospective clinical trials have been conducted by the 'Head Start' (HS) Consortium in which young children with newly-diagnosed malignant central nervous system (CNS) tumors were treated with induction chemotherapy follo
Autor:
Ziad Khatib, Doured Daghistani, Soumen Khatua, Cassie Kline, Sharon Gardner, Tobey J. MacDonald, Dolly Aguilera, Joshua E. Allen, Jeffrey C. Allen, Wafik Zaky, Nicholas A Vitanza, Maryam Fouladi, Carl Koschmann, Yazmin Odia, Rohinton Tarapore, Wolfgang Oster, Matthew Hall, Susan L. McGovern, Guangrong Lu
Publikováno v:
Journal of Clinical Oncology. 38:3619-3619
3619 Background: ONC201 is a first-in-class DRD2 antagonist and ClpP agonist that has demonstrated promising activity in high-grade glioma preclinical models and radiographic regressions with single agent ONC201 in recurrent H3 K27M-mutant glioma pat
Autor:
Ashley Love Sumrall, Yazmin Odia, Carl Koschmann, Rohinton Tarapore, Nicole Shonka, Oncoceutics Team Koschmann Lab, Yoshie Umemura, Timothy F. Cloughesy, Tracy T. Batchelor, Benjamin M. Ellingson, Joshua E. Allen, Matthew Hall, Nicholas Butowski, Rebecca Harrison, Isabel Arrillaga-Romany, Sharon Gardner, Patrick Y. Wen, John de Groot, Sylvia Kurz, Minesh P. Mehta, Abed Rahman Kawakibi
Publikováno v:
Journal of Clinical Oncology. 38:3617-3617
3617 Background: Diffuse midline gliomas, H3 K27M-mutant are associated with a poor prognosis compared to H3 wild-type gliomas and have no effective therapy following first-line radiation. ONC201 is a bitopic DRD2 antagonist and allosteric ClpP agoni
Autor:
Volker Hovestadt, Sama Ahsan, Dimitris G. Placantonakis, Thales Papagiannakopoulos, Sharon Gardner, Arline Faustin, Kasthuri Kannan, Charles G. Eberhart, Stefan M. Pfister, Olga Aminova, Shiyang Wang, James M. Stafford, Adriana Heguy, Jeffrey H. Wisoff, Luis Chiriboga, Marc K. Rosenblum, Karina Ray, Jonathan Serrano, Elke Pfaff, Igor Dolgalev, David Zagzag, Matthias A. Karajannis, John G. Golfinos, Stacie Stapleton, David Capper, Matija Snuderl, Sarah E. LeBoeuf, David T.W. Jones, Lukas Chavez
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Pineoblastoma is a rare and highly aggressive brain cancer of childhood, histologically belonging to the spectrum of primitive neuroectodermal tumors. Patients with germline mutations in DICER1, a ribonuclease involved in microRNA processing, have in
Autor:
Shiyang Wang, James M. Stafford, Charles G. Eberhart, Sharon Gardner, Dimitris G. Placantonakis, Volker Hovestadt, David T.W. Jones, Lukas Chavez, Adriana Heguy, Stacie Stapleton, Jonathan Serrano, Matthias A. Karajannis, Sarah E. LeBoeuf, Matija Snuderl, Luis Chiriboga, Olga Aminova, Karina Ray, Marc K. Rosenblum, David Capper, Sama Ahsan, Kasthuri Kannan, Jeffrey H. Wisoff, Elke Pfaff, Igor Dolgalev, Thales Papagiannakopoulos, John G. Golfinos, Arline Faustin, Stefan M. Pfister, David Zagzag
BACKGROUND: Pineoblastoma is a rare and highly aggressive brain cancer of childhood, histologically belonging to the spectrum of primitive neuroectodermal tumors. Patients with germline mutations in DICER1, a ribonuclease involved in microRNA process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e93b59df9c372fc8673efa1ea4af05e
https://europepmc.org/articles/PMC6012258/
https://europepmc.org/articles/PMC6012258/
Autor:
An Hanna, Seema Patel, Sharon Gardner, Matija Snuderl, Benjamin Liechty, Matthias A. Karajannis, Allen Jeffrey, Shiyang Wang
Program cell death ligand-1 (PD-L1) membranous expression on >5% tumor cells (PD-L1 positive tumors) is an unfavorable prognostic marker in many solid tumors. We previously showed that approximately 40% of neurofibromatosis type 2 (NF2) meningiomas a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e385a1f56212cfb4fd7eb9b7d259ab1b
https://europepmc.org/articles/PMC6012234/
https://europepmc.org/articles/PMC6012234/
Autor:
Jonathan L. Finlay, Mohammad H Abu Arja, Sharon Gardner, Lubna S Mehyar, Diana S Osorio, Scott L. Coven
INTRODUCTION: The incidence of hepatotoxicity has never been reported for intensive induction chemotherapy regimens for young children with primary malignant CNS tumors. We report our comprehensive review of available data on patients enrolled on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0db765c6807cabe0d4bc93e95d888ac
https://europepmc.org/articles/PMC6012657/
https://europepmc.org/articles/PMC6012657/
Publikováno v:
Schultz, D, G. Fairman Jr., J, Anderson, S & Gardner, S 2017, ' Build Your Own Earth : A Web-Based Tool for Exploring Climate-Model Output in Teaching and Research ', Bulletin of the American Meteorological Society . https://doi.org/10.1175/BAMS-D-16-0121.1
Build Your Own Earth was designed as a web-based tool for the user to select various characteristics of a planet and see what the climate of that planet would be like. Because of the limitations of computer resources, presimulated Earths were run usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b68444ed09ac0748d2f4eb7a17557e
https://www.research.manchester.ac.uk/portal/en/publications/build-your-own-earth(a4ca75b2-0074-4a4b-b825-4fead0cbd1bc).html
https://www.research.manchester.ac.uk/portal/en/publications/build-your-own-earth(a4ca75b2-0074-4a4b-b825-4fead0cbd1bc).html
Autor:
Sarah Milla, Matthew Winfeld, Els Fieremans, Matthias A. Karajannis, Joseph A. Helpern, Jens H. Jensen, Vitria Adisetiyo, Jeffrey C. Allen, Sharon Gardner
Publikováno v:
Journal of Pediatric Neuroradiology. :301-305
The purpose of this study is to determine the accuracy with which a non-Gaussian measure of diffusion, mean kurtosis (MK), predicts the histologic grade of pediatric brain tumors. After institutional review board approval, 21 World Health Organizatio
Autor:
Sharon Gardner, Jeffrey C. Allen, Andrea Cappellano, Clara Belessiotis, Nicholas G. Gottardo, Nasjla S. DaSilva, Mark Weinblatt, Jonathan L. Finlay, Girish Dhall, Blanca Diez, Rachel Pruitt
Publikováno v:
Pediatric Blood & Cancer. 62:1920-1924
Objectives To evaluate patterns of relapse and outcome in patients newly diagnosed with CNS Mixed Malignant GCT (MMGCT) treated initially with chemotherapy alone. Methods A retrospective chart review was conducted using all 25 patients enrolled on th