Zobrazeno 81 - 90
of 110
pro vyhledávání: '"Shanmugam Nagarajan"'
Publikováno v:
Molecular immunology. 38(7)
Receptors for the Fc region of IgG (FcgammaR) are expressed as membrane-bound and soluble forms in inflammatory cells. These receptors mediate a variety of immunoregulatory functions. FcgammaR-bearing neutrophils and macrophages play a major role in
Autor:
Rcm. Simmen, T Rogers, Shanmugam Nagarajan, RS Fox, Jmp Pabona, Leah Hennings, Omar M. Rahal, Ying Su
Publikováno v:
Cancer Research. 70:PD02-03
Breast cancer risk is highly modified by environmental factors including diet. Previously, we showed that dietary intake of soy protein isolate (SPI) decreased mammary tumor incidence and increased mammary tumor latency in rats relative to those fed
Publikováno v:
Protein expression and purification. 17(2)
Tumor cells can be modified to express immunostimulatory molecules such as B7-1 by protein transfer using purified glycosylphosphatidylinositol-anchored B7-1 (GPI-B7-1). In this study recombinant baculovirus encoding GPI-B7-1 (vBacB7-1(GPI)) was esta
Publikováno v:
Journal of immunological methods. 184(2)
Purified glycosyl phosphatidyl inositol (GPI)-anchored cell surface proteins can be reincorporated spontaneously into the cell membrane by incubating the cells with these proteins. This unique property provides a novel way of introducing cell surface
Publikováno v:
Human Genetics. 95
PIG-A, the gene encoding the glycoinositol phospholipid anchor synthetic element that is defective in paroxysmal nocturnal hemoglobinuria (PNH), resides on the X chromosome. In the course of analyses of PIG-A genetic alterations in PNH patients, poly
Autor:
N. Shanmugam Nagarajan, Muralidharan Kaliaperumal, M. Gopalakrishnan Sethuraman, R. Priya Rao, C. Narayanan Manoj
Publikováno v:
Magnetic Resonance in Chemistry. 41:227-228
Two methoxylated isoflavones were isolated form the roots of Dalbergia horrida. These compounds show great promise as pharmaceutical agents. The 1H and 13C NMR spectra of the compounds were completely assigned by using a combination of 2D NMR experim
Publikováno v:
The Journal of Immunology. 186:112.1-112.1
The presence of anti-oxLDL IgG is well documented in clinical and animal studies. However, the role for FcγRs to the progression of atherosclerosis has not been studied in detail. In the present study, we investigated the role for activating FcγR i
Publikováno v:
The Journal of Immunology. 186:117.1-117.1
Several recent reports showed that IL-17 plays a pro-atherogenic role in atherosclerosis. However the underlying mechanism by which IL-17 promotes the pathogenesis of atherosclerosis remains unclear. The expression of vascular adhesion molecule (VCAM
Autor:
Matthew E. Ferguson, Xianli Wu, Shanmugam Nagarajan, Jin-Ran Chen, Thomas M. Badger, Oxana P. Lazarenko, Jie Kang, Chenghui Xie
Publikováno v:
Food & Function. 2:588
Blueberries have recently been reported to reduce atherosclerotic lesion progression in apoE deficient (apoE−/−) mice. However, the underlying mechanisms are not fully understood. The objective of this study was to determine whether lowbush blueb
Autor:
Shanmugam Nagarajan
Publikováno v:
The Journal of Immunology. 182:94.24-94.24
OxLDL generated during hyperlipidemia is known to induce an autoimmune response resulting in the production of anti-oxLDL IgG. In humans and in the hyperlipidemic mouse model, the titer of autoantibodies against oxLDL correlates with the progression