Zobrazeno 61 - 70
of 89
pro vyhledávání: '"Shaney L. Barratt"'
Autor:
David O. Bates, Nicholas Beazley-Long, Richard P. Hulse, Sebastian Oltean, Maria Peiris-Pagès, Nikita Ved, Xi Ye, Rebecca R. Foster, Domingo J. Tortonese, Maria J. C. Machado, Steven J. Harper, Andrew V. Benest, Shaney L Barratt, Lucy F. Donaldson
Publikováno v:
Bates, D O, Beazley-Long, N, Benest, A, Ye, X, Ved, N, Hulse, R, Barratt, S, Machado, M, Donaldson, L F, Harper, S, Peiris-Pages, M, Tortonese, D, Oltean, S & Foster, R R 2018, ' Physiological Role of Vascular Endothelial Growth Factors as Homeostatic Regulators ', Comprehensive Physiology, vol. 8, no. 3, pp. 955-979 . https://doi.org/10.1002/cphy.c170015
Comprehensive Physiology
Comprehensive Physiology
The vascular endothelial growth factor (VEGF) family of proteins are key regulators of physiological systems. Originally linked with endothelial function, they have since become understood to be principal regulators of multiple tissues, both through
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 5, p 1269 (2018)
Barratt, S L, Flower, V A, Pauling, J D & Millar, A B 2018, ' VEGF (Vascular Endothelial Growth Factor) and Fibrotic Lung Disease ', International Journal of Molecular Sciences, vol. 19, no. 5, 1269 . https://doi.org/10.3390/ijms19051269
International Journal of Molecular Sciences
Barratt, S L, Flower, V A, Pauling, J D & Millar, A B 2018, ' VEGF (Vascular Endothelial Growth Factor) and Fibrotic Lung Disease ', International Journal of Molecular Sciences, vol. 19, no. 5, 1269 . https://doi.org/10.3390/ijms19051269
International Journal of Molecular Sciences
Interstitial lung disease (ILD) encompasses a group of heterogeneous diseases characterised by varying degrees of aberrant inflammation and fibrosis of the lung parenchyma. This may occur in isolation, such as in idiopathic pulmonary fibrosis (IPF) o
Autor:
Ian Cliff, Huzaifa Adamali, Naveed Mustfa, Shaney L Barratt, Nazia Chaudhuri, Rachel Jones, Anna C. Bibby, Jonathon Shaw, Helen Stone
Publikováno v:
Barratt, SL, Shaw, J, Jones, R, Bibby, A, Adamali, H, Mustfa, N, Cliff, I, Stone, H & Chaudhuri, N 2018, ' Physiological predictors of Hypoxic Challenge Testing (HCT) outcomes in Interstitial Lung Disease (ILD). ', Respiratory Medicine . https://doi.org/10.1016/j.rmed.2017.12.015
Barratt, S L, Shaw, J, Jones, R, Bibby, A, Adamali, H, Mustfa, N, Cliff, I, Stone, H & Chaudhuri, N 2018, ' Physiological predictors of Hypoxic Challenge Testing (HCT) outcomes in Interstitial Lung Disease (ILD) ', Respiratory Medicine, vol. 135, pp. 51-56 . https://doi.org/10.1016/j.rmed.2017.12.015
Barratt, S L, Shaw, J, Jones, R, Bibby, A, Adamali, H, Mustfa, N, Cliff, I, Stone, H & Chaudhuri, N 2018, ' Physiological predictors of Hypoxic Challenge Testing (HCT) outcomes in Interstitial Lung Disease (ILD) ', Respiratory Medicine, vol. 135, pp. 51-56 . https://doi.org/10.1016/j.rmed.2017.12.015
Background Pre-flight risk assessments are currently recommended for all Interstitial Lung Disease (ILD) patients. Hypoxic challenge testing (HCT) can inform regarding the need for supplemental in-flight oxygen but variables which might predict the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::825a1959b0d2d8962d63aa92d951af53
https://www.research.manchester.ac.uk/portal/en/publications/physiological-predictors-of-hypoxic-challenge-testing-hct-outcomes-in-interstitial-lung-disease-ild(f01dc0eb-cf78-489c-bd0b-879935bda755).html
https://www.research.manchester.ac.uk/portal/en/publications/physiological-predictors-of-hypoxic-challenge-testing-hct-outcomes-in-interstitial-lung-disease-ild(f01dc0eb-cf78-489c-bd0b-879935bda755).html
Publikováno v:
Managing pleural disease: from intervention to conservation.
Background Traumatic pneumothoraces are a common consequence of major trauma. Despite this, there is a paucity of literature regarding their optimal management, including the role of conservative treatment. The aim of this study was to assess the tre
Autor:
Thomas Blythe, Gavin I. Welsh, David O. Bates, Khadija Ourradi, Caroline Jarrett, Shaney L Barratt, Ann B. Millar
Publikováno v:
Respiratory Research
Respiratory Research, Vol 19, Iss 1, Pp 1-5 (2018)
Barratt, S L, Blythe, T, Ourradi, K, Jarrett, C, Welsh, G I, Bates, D O & Millar, A B 2018, ' Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF) ', Respiratory Research, vol. 19, 9 . https://doi.org/10.1186/s12931-017-0711-x
Respiratory Research, Vol 19, Iss 1, Pp 1-5 (2018)
Barratt, S L, Blythe, T, Ourradi, K, Jarrett, C, Welsh, G I, Bates, D O & Millar, A B 2018, ' Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF) ', Respiratory Research, vol. 19, 9 . https://doi.org/10.1186/s12931-017-0711-x
Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The ro
Publikováno v:
Pleural and Mediastinal Malignancies.
Aims: Traumatic pneumothoraces are a common consequence of major trauma. Despite this, there is a paucity of literature regarding their optimal management, including the role of conservative treatment. The aim of this study was to assess the treatmen
Autor:
Thomas J. Hames, Michael J. Day, Gavin I. Welsh, Yan Qiu, David O. Bates, Shaney L Barratt, Toby M. Maher, Khadija Ourradi, Ann B. Millar, Caroline Jarrett, Thomas Blythe, Chris J. Scotton, Golda Shelley-Fraser, Sebastian Oltean, Steve J Harper
Publikováno v:
American journal of respiratory and critical care medicine. 196(4)
RATIONALE: Fibrosis after lung injury is related to poor outcome, and idiopathic pulmonary fibrosis (IPF) can be regarded as an exemplar. Vascular endothelial growth factor (VEGF)-A has been implicated in this context, but there are conflicting repor
Publikováno v:
Chest. 153(4)
Traumatic pneumothoraces are a common consequence of major trauma. Despite this, there is a paucity of literature regarding their optimal management, including the role of conservative treatment. The aim of this study was to assess the treatment, com
Autor:
Clare Kendall, Michelle Morales, Nikki Jordan, Toby Speirs, Charles Sharp, A. S. G. Edwards, Sarah Mulholland, Shaney L Barratt, Rachel Gunary, Khaled Al Jboor, Patricia Meek, Heather Lamb, Huzaifa Adamali
Publikováno v:
BMJ Open Respiratory Research
IntroductionPatients with progressive idiopathic fibrotic interstitial lung disease (ILD), such as those with idiopathic pulmonary fibrosis (IPF), can have an aggressive disease course, with a median survival of only 3–5 years from diagnosis. The p
Publikováno v:
Journal of Clinical Medicine, Vol 7, Iss 8, p 201 (2018)
Barratt, S, Creamer, A, hayton, C & Chaudhuri, N 2018, ' Idiopathic Pulmonary Fibrosis (IPF) : An Overview ', Journal of Clinical Medicine, vol. 7, no. 8, 201 . https://doi.org/10.3390/jcm7080201
Barratt, S L, Creamer, A, Hayton, C & Chaudhuri, N 2018, ' Idiopathic Pulmonary Fibrosis (IPF) : An Overview ', Journal of Clinical Medicine, vol. 7, no. 8, 201 . https://doi.org/10.3390/jcm7080201, https://doi.org/10.3390/jcm7080201
Journal of Clinical Medicine
Barratt, S, Creamer, A, hayton, C & Chaudhuri, N 2018, ' Idiopathic Pulmonary Fibrosis (IPF) : An Overview ', Journal of Clinical Medicine, vol. 7, no. 8, 201 . https://doi.org/10.3390/jcm7080201
Barratt, S L, Creamer, A, Hayton, C & Chaudhuri, N 2018, ' Idiopathic Pulmonary Fibrosis (IPF) : An Overview ', Journal of Clinical Medicine, vol. 7, no. 8, 201 . https://doi.org/10.3390/jcm7080201, https://doi.org/10.3390/jcm7080201
Journal of Clinical Medicine
Idiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic, progressive scarring of the lungs and the pathological hallmark of usual interstitial pneumonia. Current paradigms suggest alveolar epithelial cell damage i