Zobrazeno 11 - 20
of 27
pro vyhledávání: '"Seong Joo Koo"'
Publikováno v:
The EMBO Journal. 30:181-193
DYT1 dystonia is caused by an autosomal dominant mutation that leads to a glutamic acid deletion in torsinA (TA), a member of the AAA+ ATPase superfamily. In this study, we identified a novel-binding partner of TA, the subunit 4 (CSN4) of CSN signalo
Autor:
Nina Kahlfeldt, Georg Krainer, Johannes G. Schäfer, Michael Krauss, Ardeschir Vahedi-Faridi, Volker Haucke, Sandro Keller, Wolfram Saenger, Seong Joo Koo
Publikováno v:
The journal of biological chemistry, 285: 2734-2749
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) is an essential determinant in clathrin-mediated endocytosis (CME). In mammals three type I phosphatidylinositol-4-phosphate 5-kinase (PIPK) enzymes are expressed, with the I gamma-p90 isoform being
Autor:
Clara D. Christ, Roman C. Hillig, Bernard Haendler, Hilmar Weinmann, Anke Mueller-Fahrnow, Naomi Barak, Markus Berger, Erik Eggert, Carlo Stresemann, Masoud Vedadi, Antonius Ter Laak, Stephan Siegel, Cora Scholten, Oleg Fedorov, Andrea Haegebarth, Amaury Ernesto Fernandez-Montalvan, Ursula Egner, Simon H. Holton, Peter Brown, Joerg Weiske, Mátyás Gorjánácz, Volker Badock, Ingo Hartung, Seong Joo Koo, Timo Stellfeld, Susanne Mueller, Kilian Huber, Cheryl H. Arrowsmith, Detlef Stoeckigt
Publikováno v:
Cancer Research. 77:5239-5239
Low reproducibility of published target validation studies as well as the frequent failure of genetic knock-down effects to phenocopy those of small molecule inhibitors have been recognized as road blocks for cancer drug discovery. Academic and indus
Autor:
L. Diaz-Saez, Hilmar Weinmann, Christoph E. Dumelin, Dawn M. Troast, Joerg Weiske, John W. Cuozzo, Ingo Hartung, Ying Zhang, James M. Bennett, Anthony D. Keefe, Didier M. Roche, Seong Joo Koo, Kilian Huber, Benno Kuropka, Oleg Federov, Matthew A. Clark, Markus Berger, Eric A. Sigel, Paolo A. Centrella, Mátyás Gorjánácz, Volker Badock, Apirat Chaikuad, Jan Hübner, Simon Holton, Holly S. Soutter, Amaury Ernesto Fernandez-Montalvan, Vincent Rodeschini
Publikováno v:
Cancer Research. 77:5084-5084
ATAD2 (ATPase family AAA-domain containing protein 2, also called ANCCA) is an epigenetic regulator that binds to chromatin through its bromodomain (BD), a motif specialized for acetyl-lysine recognition. ATAD2 directly associates with multiple trans
Autor:
Henning Urlaub, Sven Truckenbrodt, Burkhard Rammner, Seong Joo Koo, Sunit Mandad, Katharina Kröhnert, Christina Schäfer, Volker Haucke, Benjamin G. Wilhelm, Silvio O. Rizzoli, Michael Krauss, Gala A. Claßen
Publikováno v:
Science
High-definition view of the synapse Individual neurons communicate with one another via their synapses, so to understand the nervous system, we need to understand in detail how the synapses are organized. Wilhelm et al. present a quantitative molecul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68626cdfc171e618d4e04bed3a4484fa
https://hdl.handle.net/11858/00-001M-0000-0019-BF7E-411858/00-001M-0000-0019-BF81-911858/00-001M-0000-0019-BF7F-211858/00-001M-0000-0019-BF82-711858/00-001M-0000-0019-BF79-E11858/00-001M-0000-0019-BF80-B11858/00-001M-0000-0019-BF83-511858/00-001M-0000-0019-BF84-3
https://hdl.handle.net/11858/00-001M-0000-0019-BF7E-411858/00-001M-0000-0019-BF81-911858/00-001M-0000-0019-BF7F-211858/00-001M-0000-0019-BF82-711858/00-001M-0000-0019-BF79-E11858/00-001M-0000-0019-BF80-B11858/00-001M-0000-0019-BF83-511858/00-001M-0000-0019-BF84-3
Autor:
M. Kasim Diril, Michael Kintscher, York Winter, Dietmar Schmitz, Martin Wienisch, Jörg Breustedt, Dmytro Puchkov, Seong Joo Koo, Tanja Maritzen, Jürgen Klingauf, Gerit Pfuhl, Volker Haucke, Natalia L. Kononenko
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 110(6): E526–E535
Neurotransmission depends on the exocytic fusion of synaptic vesicles (SVs) and their subsequent reformation either by clathrin-mediated endocytosis or budding from bulk endosomes. How synapses are able to rapidly recycle SVs to maintain SV pool size
Autor:
James E. Bradner, Simon Holton, Christopher J. Ott, Sarah Vittori, Oliver von Ahsen, Amaury Ernesto Fernandez-Montalvan, Mátyás Gorjánácz, Volker Badock, Seong Joo Koo
Publikováno v:
Cancer Research. 76:4539-4539
ATAD2 (ATPase family AAA domain-containing protein 2) is an epigenetic regulator which associates with chromatin through its Bromodomain specialized in Acetyl-Lys binding of histones. ATAD2 was also shown to directly associate with multiple transcrip
Autor:
Dietmar Schmitz, York Winter, Tanja Maritzen, Gerit Pfuhl, Natalia L. Kononenko, Jan Schmoranzer, Seong Joo Koo, Volker Haucke, Takeshi Sakaba, Michael Kintscher, M. Kasim Diril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1112fac75dcb26f3978ae3ab6346bc7
https://avesis.deu.edu.tr/publication/details/26546a5a-d8c7-48c4-ace7-00265903b478/oai
https://avesis.deu.edu.tr/publication/details/26546a5a-d8c7-48c4-ace7-00265903b478/oai
Publikováno v:
Biology of the cell. 104(10)
Dynamic flux of membrane between intracellular compartments is a key feature of all eukaryotic cells. Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) play a crucial role in membrane dynamics by facilitating membrane fu
Publikováno v:
Cellular logistics, 1(4): 168-172
Communication between neurons largely occurs at chemical synapses involving conversion of electric to chemical signals. Chemical neurotransmission involves the action potential-driven release of neurotransmitters from synaptic vesicles (SVs) at presy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b328d7514486237f7cb53bd29c74970
https://europepmc.org/articles/PMC3265930/
https://europepmc.org/articles/PMC3265930/