Zobrazeno 21 - 30
of 30
pro vyhledávání: '"Semira Sheikh"'
Autor:
Enrique Amaya, Imad M. Awan, Hugo J. Bellen, Alessandro Bertero, David Brindley, Stephanie Brown, Eleanor Jane Budge, Eleni Chantzoura, John Collin, Amanda S. Coutts, Karel Dorey, Jefte M. Drijvers, Tomasz Gwozdz, Gregory A. Hawkins, Shoko Ishibashi, Tyler Jacks, Mehdi Jalali, Morteza Jalali, Sonali Joshi, Keisuke Kaji, Nicholas B. La Thangue, Laurens J. Lambert, Robert Lea, Martyna Lukoseviciute, Paul Martin, Mandar D. Muzumdar, Frederick D. Park, Cory A. Perugino, Adam Pettitt, David Pettitt, Shiv Pillai, Tannishtha Reya, William M. Rideout, MacKenna Roberts, Ian M. Rosenberg, Francesca Y.L. Saldanha, Roman Sasik, Charis-P. Segeritz, Semira Sheikh, James Smith, Ludovic Vallier, Michael F. Wangler, Dihua Yu, Justyna Zaborowska
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d10cd44acceecb1af07e50a4bf1145b
https://doi.org/10.1016/b978-0-12-803077-6.00024-2
https://doi.org/10.1016/b978-0-12-803077-6.00024-2
Over the last 30 years, the transfection of DNA or RNA into mammalian cells has evolved into an ever more sophisticated research tool for the investigation of gene expression and protein function. Transfection is used to describe the process of intro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::753fbd788a577d42d41155c5e00e2538
https://doi.org/10.1016/b978-0-12-803077-6.00011-4
https://doi.org/10.1016/b978-0-12-803077-6.00011-4
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1436
Lysine acetylation in proteins is one of the most abundant posttranslational modifications in eukaryotic cells. The dynamic homeostasis of lysine acetylation and deacetylation is dictated by the action of histone acetyltransferases (HAT) and histone
The last decade has brought about a vastly improved understanding of the important role that epigenetic changes play in cancer biology. Epigenetic therapy seeks to harness recent insights into the dynamic nature of the mechanisms involved in epigenet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::034f4e7476b9482b232ac9c5cc366e9a
https://doi.org/10.1016/b978-0-12-802208-5.00015-1
https://doi.org/10.1016/b978-0-12-802208-5.00015-1
Autor:
Elizabeth J. Soilleux, Finn Tysoe, Semira Sheikh, David J. Kerr, Graham P. Collins, Mark R. Middleton, Richard Cousins, Lai Mun Wang, Victoria K Woodcock, Avinash Gupta, John Whittaker, Toby A. Eyre, Nicholas B. La Thangue
Publikováno v:
Blood. 128:1817-1817
Introduction CXD101 is a class I-selective HDAC inhibitor (HDACi)with no demonstrable activity against HDAC class II in non-clinical studies. CXD101 induces specific HDAC inhibition and subsequent to that, enhanced histone acetylation in a time and d
Publikováno v:
Blood. 128:1766-1766
Introduction Histone deacetylase inhibitors (HDI) are promising new agents for the treatment of haematological malignancy including lymphoma. HDI have potent anti-proliferative effects in cell-based studies; in the clinical setting, however, the pict
Autor:
David J. Kerr, John Whittaker, Semira Sheikh, R Cousins, Graham P. Collins, Avinash Gupta, Elizabeth J. Soilleux, N B La Thangue, Lai Mun Wang, Toby A. Eyre, Finn Tysoe, V Woodcock, Mark R. Middleton
Publikováno v:
Annals of Oncology. 27:vi544
Autor:
Tim Littlewood, Semira Sheikh
Publikováno v:
Expert review of hematology. 3(6)
Anemia in cancer patients is common and often associated with decreased survival and quality-of-life scores. The introduction of erythropoiesis-stimulating agents (ESAs) for the treatment of anemia in patients with solid tumors and nonmyeloid maligna
Publikováno v:
British Journal of Haematology. 163:550-550
Publikováno v:
Scopus-Elsevier
Besides the genetic information thath is encoded by DNA, heritable information can also be passed on without relying on changes in the nucleotide sequence of DNA, a phenomenon known as epigenetics. Gene expression in eukaryotes is partly regulated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74499e31bd160d673cfa26aeb877f4f6
http://www.scopus.com/inward/record.url?eid=2-s2.0-84922762639&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84922762639&partnerID=MN8TOARS
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