Zobrazeno 21 - 30
of 406
pro vyhledávání: '"Seigo Kinuya"'
Autor:
Muammar Fawwaz, Kenji Mishiro, Ryuichi Nishii, Akira Makino, Yasushi Kiyono, Kazuhiro Shiba, Seigo Kinuya, Kazuma Ogawa
Publikováno v:
Pharmaceuticals, Vol 14, Iss 3, p 256 (2021)
Activating double mutations L858R/T790M in the epidermal growth factor receptor (EGFR) region are often observed as the cause of resistance to tyrosine kinase inhibitors (TKIs). Third-generation EGFR-TKIs, such as osimertinib and rociletinib (CO-1686
Externí odkaz:
https://doaj.org/article/3739a9aa6fb84b5096251956403b7b64
Autor:
Hideaki Shiga, Junichi Taki, Koichi Okuda, Naoto Watanabe, Hisao Tonami, Hideaki Nakagawa, Seigo Kinuya, Takaki Miwa
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
Abstract Idiopathic olfactory disorder is resistant to treatment, and the recovery time is long. This study investigated the prognostic value of the migration of nasally administered thallium-201 to the olfactory bulb (thallium migration to the OB),
Externí odkaz:
https://doaj.org/article/2626cee2c6614bbeb3fcb8f89f699011
Publikováno v:
Molecules, Vol 26, Iss 1, p 41 (2020)
The purpose of this study is to develop peptide-based platelet-derived growth factor receptor β (PDGFRβ) imaging probes and examine the effects of several linkers, namely un-natural amino acids (D-alanine and β-alanine) and ethylene-glycol (EG), o
Externí odkaz:
https://doaj.org/article/545686bf8a4244529f40f7e878a25650
Autor:
Hiroshi Wakabayashi, Daiki Kayano, Anri Inaki, Raita Araki, Rie Kuroda, Norihito Akatani, Takafumi Yamase, Satoru Watanabe, Tomo Hiromasa, Yuji Kunita, Hiroshi Mori, Shintaro Saito, Yasuhiro Ikawa, Toshihiro Fujiki, Seigo Kinuya
Publikováno v:
Diagnostics, Vol 10, Iss 9, p 663 (2020)
123I-meta-iodobenzylguanidine (123I-mIBG) scintigraphy is used for evaluating disease extent in children with neuroblastoma. 131I-mIBG therapy has been used for evaluation in children with high-risk neuroblastoma, and post-therapy 131I-mIBG scintigra
Externí odkaz:
https://doaj.org/article/66f78a23b1f946638aa7f886539e7062
Autor:
Muammar Fawwaz, Kenji Mishiro, Ryuichi Nishii, Izumi Sawazaki, Kazuhiro Shiba, Seigo Kinuya, Kazuma Ogawa
Publikováno v:
Molecules, Vol 25, Iss 12, p 2914 (2020)
Rociletinib (CO-1686), a 2,4-diaminopyrimidine derivative, is a highly potent tyrosine kinase inhibitor (TKI) that acts on epidermal growth factor receptor (EGFR) with L858R/T790M mutations. We supposed radioiodinated CO-1686 would function as a usef
Externí odkaz:
https://doaj.org/article/d1c454af90f44a039d9f817f84e13ef6
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 3, Iss 1, Pp 26-34 (2015)
Objective(s): We investigated a frequency of lower extremity uptake on the radioactive iodine (RAI) whole body scan (WBS) after RAI treatment in patients with differentiated thyroid cancer, in order to retrospectively examine whether or not the frequ
Externí odkaz:
https://doaj.org/article/f44eed615e1e4f979e25f6668db38b21
Autor:
Satoshi Kato, Hideki Murakami, Anri Inaki, Takafumi Mochizuki, Satoru Demura, Junsuke Nakase, Katsuhito Yoshioka, Noriaki Yokogawa, Takashi Igarashi, Naoki Takahashi, Noritaka Yonezawa, Seigo Kinuya, Hiroyuki Tsuchiya
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172934 (2017)
BACKGROUND:Exercise is one of the few treatments that provide significant improvements in chronic low back pain (CLBP). We developed an innovative exercise device for abdominal trunk muscles. This device can be used in a sitting or standing position
Externí odkaz:
https://doaj.org/article/f9aff37174334503ba903fd42b597980
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 1, Iss 1, Pp 39-43 (2013)
Mitochondria play an important role in energy production for the cell. The proper function of a myocardial cell largely depends on the functional capacity of the mitochondria. Therefore it is necessary to establish a novel and reliable method for a n
Externí odkaz:
https://doaj.org/article/26581f6ac8ed4c0780a26a15701d66a3
Autor:
Daiki Kayano, Junichi Taki, Anri Inaki, Hiroshi Wakabayashi, Ayane Nakamura, Makoto Fukuoka, Seigo Kinuya
Publikováno v:
Asia Oceania Journal of Nuclear Medicine and Biology, Vol 1, Iss 1, Pp 20-26 (2013)
Objective: The current study aimed to determine the efficacy of radioiodine-131 (131I) ablation therapy with thyroid hormone replacement one day before 131I administration in patients with well-differentiated thyroid cancer (DTC). Methods: This retro
Externí odkaz:
https://doaj.org/article/82534f83f2da42518cd591a8b46202e5
Autor:
Izumi Uno, Takashi Kozaka, Daisuke Miwa, Yoji Kitamura, Mohammad Anwar-Ul Azim, Kazuma Ogawa, Junichi Taki, Seigo Kinuya, Kazuhiro Shiba
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146719 (2016)
PURPOSE:To develop a superior VAChT imaging probe for SPECT, radiolabeled (-)-OIDV and (+)-OIDV were isolated and investigated for differences in their binding affinity and selectivity to VAChT, as well as their in vivo activities. PROCEDURES:Radioio
Externí odkaz:
https://doaj.org/article/862b14d59e374085b7750bc06354c85f