Zobrazeno 11 - 17
of 17
pro vyhledávání: '"Saad Alobid"'
Autor:
Appu Rathinavelu, Ali Alaseem, Anupam Bishayee, Saad Alobid, Priya Dondapati, Khalid Alhazzani
Publikováno v:
Seminars in cancer biology. 56
Matrix metalloproteinases (MMPs) are members of zinc-dependent endopeptidases implicated in a variety of physiological and pathological processes. Over the decades, MMPs have been studied for their role in cancer progression, migration, and metastasi
Autor:
Thanigaivelan Kanagasabai, Appu Rathinavelu, Umamaheswari Natarajan, Khalid Alhazzani, Aiyavu Chinnaiyan, Priya Dondapati, Ali Alaseem, Thiagarajan Venkatesan, Ruben Schwartz, Saad Alobid, Sivanesan Dhandayuthapani
Publikováno v:
Cells
Cells; Volume 7; Issue 5; Pages: 41
Cells, Vol 7, Iss 5, p 41 (2018)
Cells; Volume 7; Issue 5; Pages: 41
Cells, Vol 7, Iss 5, p 41 (2018)
The Murine Double Minute 2 (MDM2) amplification or overexpression has been found in many tumors with high metastatic and angiogenic ability. Our experiments were designed to explore the impact of MDM2 overexpression, specifically on the levels of ang
Autor:
Thanigaivelan Kanagasabai, Appu Rathinavelu, Thiagarajan Venkatesan, Khalid Alhazzani, Saad Alobid, Priya Dondapati, Ali Alaseem
Publikováno v:
Cancer Research. 77:2013-2013
The matrix metalloprotenases (MMPs) are a family of zinc-dependent endopeptidase and have proteolysis activity which found to impact several physiological and pathophysiological conditions including cancer. In cancer, over 20 types of MMPs promote in
Publikováno v:
Cancer Research. 77:467-467
Recent studies have shown the crucial role of miRNAs in regulating cancer initiation, progression and metastatic process via influencing gene expression patterns. However, the distinct mechanism by which miRNA regulates tumorigenesis remains as an ar
Autor:
Ali Alaseem, Thiagarajan Venkatesan, Saad Alobid, Priya Dondapati, Khalid Alhazzani, Appu Rathinavelu
Publikováno v:
Cancer Research. 76:1839-1839
MDM2 gene is a cellular proto-oncogene amplified in 25-40% of all human cancers and regulates cell proliferation, senescence, and apoptosis through targeting p53. It is widely speculated that MDM2 protein is not only responsible for tumorigenesis via
Publikováno v:
Cancer Research. 76:1844-1844
MDM2 is a multifunctional oncogene that has been associated with highly prevalent and aggressive cancers such as colon and prostate. MDM2 promotes a negative regulation of p53 activities and thus can prevent several of p53 protective effects includin
Publikováno v:
Cancer Research. 76:3257-3257
Angiogenesis is an essential key process in tumor growth, invasion, and metastasis. Several angiogenesis inhibitors have been clinically proven to treat a wide variety of cancer types. These agents target either the vascular endothelial growth factor
- [1]
- « Předchozí
- 1
- 2