Zobrazeno 81 - 90
of 136
pro vyhledávání: '"Rosario Osta"'
Autor:
Carlos Moreno, Juan José Badiola, Eva Monleón, Jaber Lyahyai, Carmen Serrano, Rosario Osta, Pilar Zaragoza, Rosa Bolea, Inmaculada Martín-Burriel
Publikováno v:
Acta Neuropathologica. 112:451-460
Although apoptosis has been implicated in the neuronal loss observed in prion diseases, the participation of apoptosis-related factors, like the Bcl-2 family of proteins, is still not clear. Moreover, there are conflicting data concerning the major r
Autor:
Inmaculada Martín-Burriel, R. Ronda, Pilar Zaragoza, Odalys Uffo, Clementina Rodellar, S. Martínez, Rosario Osta
Publikováno v:
Animal Genetic Resources Information. 39:15-24
ResumenEn el presente estudio se presentan los primeros resultados de la determinación de la estructura genética de tres poblaciones de ganado bovino autóctono cubano: Criollo de Cuba, Cebú Cubano y Siboney de Cuba, para los loci de seis proteín
Publikováno v:
Proceedings of the National Academy of Sciences. 99:3234-3239
During development and also in adulthood, synaptic connections are modulated by neuronal activity. To follow such modifications in vivo , new genetic tools are designed. The nontoxic C-terminal fragment of tetanus toxin (TTC) fused to a reporter gene
Presymptomatic electrophysiological tests predict clinical onset and survival in SOD1(G93A) ALS mice
Publikováno v:
Musclenerve. 50(6)
We assessed the predictive value of electrophysiological tests as a marker of clinical disease onset and survival in superoxide-dismutase 1 (SOD1)(G93A) mice.We evaluated the accuracy of electrophysiological tests in differentiating transgenic versus
Autor:
Renzo Mancuso, Laura Mòdol, Rosario Osta, Ana Belén Granado-Serrano, Manel Portero-Otin, Jaume del Valle, Mercè Pallàs, Xavier Navarro, Omar Ramírez-Núñez, Anna Andaluz Martínez
Publikováno v:
Neurotherapeutics
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease that causes progressive paralysis and death due to degeneration of motoneurons in spinal cord, brainstem and motor cortex. Nowadays, there is no effective therapy and pat
Autor:
Vesna Selaković, Branka Janać, Ana C. Calvo, Lidija Radenovic, Rosario Osta, Sara Oliván, Amaya Rando
Publikováno v:
Brain Research Bulletin
The tetanus toxin C (TTC) fragment capacity of being transported in a retrograde way through motoneurons and its nontoxic nature opens the door to a new promising therapeutic strategy for neurodegenerative diseases. In this study, the TTC effect was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55f1a287ba9c77e1e5d446cb57ca4e5
http://ibiss-r.rcub.bg.ac.rs/123456789/3787
http://ibiss-r.rcub.bg.ac.rs/123456789/3787
Publikováno v:
BioMed Research International, Vol 2014 (2014)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
BioMed Research International
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
BioMed Research International
Sex bias has been described nowadays in biomedical research on animal models, although sexual dimorphism has been confirmed widely under pathological and physiological conditions. The main objective of our work was to study the sex differences in con
Autor:
Carmen Arnal, Joaquín C. Surra, Rosario Osta, Roberto Martínez-Beamonte, Ana C. Calvo, Sara Oliván, Jesús Osada, Raquel Manzano
Publikováno v:
The Journal of nutritional biochemistry. 25(8)
Amyotrophic lateral sclerosis is a neurodegenerative disease associated with mutations in antioxidant enzyme Cu/Zn-superoxide dismutase 1. Albeit there is no treatment for this disease, new insights related to an exacerbated lipid metabolism have bee
Autor:
Rosario Osta, Alberto García-Redondo, Pilar Zaragoza, Sara Oliván, Raquel Manzano, Janne M. Toivonen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e89065 (2014)
PLoS ONE, Vol 9, Iss 2, p e89065 (2014)
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively debilitates neuronal cells that control voluntary muscle activity. Biomarkers are urgently needed to facilitate ALS diagnosis and prognosis, and as indicators of
Publikováno v:
Gene Therapy-Tools and Potential Applications
In particular, ALS belongs to the group of motor neuron diseases, involving the loss of cortex, brainstem, and spinal cord motor neurons that result in muscle paralysis [1]. Motor neurons, which are localized in the brain, brainstem and spinal cord,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda778d273d4f5fd85a0d9c4a951747b
http://www.intechopen.com/articles/show/title/gene-therapy-based-on-fragment-c-of-tetanus-toxin-in-als-a-promising-neuroprotective-strategy-for-th
http://www.intechopen.com/articles/show/title/gene-therapy-based-on-fragment-c-of-tetanus-toxin-in-als-a-promising-neuroprotective-strategy-for-th