Zobrazeno 41 - 50
of 102
pro vyhledávání: '"Ros Eeles"'
Autor:
Mahbubl, Ahmed, Leila, Dorling, Sarah, Kerns, Laura, Fachal, Rebecca, Elliott, Matt, Partliament, Barry S, Rosenstein, Ana, Vega, Antonio, Gómez-Caamaño, Gill, Barnett, David P, Dearnaley, Emma, Hall, Matt, Sydes, Neil, Burnet, Paul D P, Pharoah, Ros, Eeles, Catharine M L, West
Publikováno v:
British Journal of Cancer
Background: Numerous germline single-nucleotide polymorphisms increase susceptibility to prostate cancer, some lying near genes involved in cellular radiation response. This study investigated whether prostate cancer patients with a high genetic risk
Autor:
William J. Catalona, Bo Johanneson, Kathleen Herkommer, Brian T. Helfand, Daniel J. Schaid, Henrik Grönberg, Jianfen Xu, Johanna Schleutker, James M. Farnham, Donghui Kan, Ingrid Oakley-Girvan, Antoine Valeri, Steve Edwards, Teuvo L.J. Tammela, Lingyi Lu, Chih-Lin Hsieh, Josef Hoegel, Ethan M. Lange, Olivier Cussenot, John D. Carpten, Lovise Maehle, Cheryl D. Cropp, William B. Isaacs, Geraldine Cancel-Tassin, Gianluca Severi, Sarah D. Isaacs, Elaine A. Ostrander, Dallas R. English, John L. Hopper, Douglas T. Easton, Joan E. Bailey-Wilson, Shannon K. McDonnell, Stephen N. Thibodeau, Fredrik Wiklund, Kerry Deutsch, Liesel M. FitzGerald, Alice S. Whittemore, Kathleen A. Cooney, Christiane Maier, Claire L. Simpson, Laura McIntosh, Lisa A. Cannon-Albright, Isaac J. Powell, Pål Møller, Janet L. Stanford, Scott J. Hebbring, Daniela Seminara, Patrick C. Walsh, William D. Foulkes, Michelle Guy, Monica Emanuelsson, Michael D. Badzioch, Walther Vogel, Nicola J. Camp, Ros Eeles, Graham G. Giles, Kathleen E. Wiley, S. Lilly Zheng
Publikováno v:
The Prostate. 72:410-426
BACKGROUND In spite of intensive efforts, understanding of the genetic aspects of familial prostate cancer (PC) remains largely incomplete. In a previous microsatellite-based linkage scan of 1,233 PC families, we identified suggestive evidence for li
Autor:
Maria A. Caligo, Carol Chu, Xianshu Wang, Senno Verhoef, Joanne L. Blum, Bruno Buecher, Amanda B. Spurdle, Theo A. M. van Os, Per Karlsson, Olga M. Sinilnikova, Sue Healey, Hanne Meijers-Heijboer, Georgia Chenevix-Trench, Marinus J. Blok, Timothy R. Rebbeck, Douglas F. Easton, Mary B. Daly, Annelie Liljegren, Margaret Cook, Christina G. Selkirk, Dominique Stoppa-Lyonnet, Mieke Kriege, Nadine Tung, Muriel Belotti, Susan Peock, Fiona Lalloo, Louise Izatt, Mads Thomassen, Henry T. Lynch, Christian F. Singer, Susan M. Domchek, Margreet G. E. M. Ausems, Tomasz Byrski, Olufunmilayo I. Olopade, Noralane M. Lindor, Claudine Isaacs, Katherine L. Nathanson, Gail E. Tomlinson, Clare Oliver, Hans Ehrencrona, Anna Jakubowska, Francine Durocher, Pascal Pujol, Debra Frost, Tuomas Heikkinen, Christine Lasset, Rosemarie Davidson, Jan Lubinski, Marie Agnés Collonge-Rame, Patricia A. Ganz, Nicoline Hoogerbrugge, Fergus J. Couch, Lesley McGuffog, Matti A. Rookus, Heli Nevanlinna, Helena Jernström, Sylvie Mazoyer, Jonathan Beesley, Judy Garber, Diana Eccles, Don M. Conroy, Xiaoqing Chen, Daphne Gschwantler-Kaulich, Tomasz Huzarski, Carole Verny-Pierre, Antonis C. Antoniou, D. Gareth Evans, Louise Marquart, Juul T. Wijnen, Ros Eeles, Peter Devilee, Laure Barjhoux, Fei Wan, Anne Catharine Dressler, Susan L. Neuhausen, Jeff Weitzel, Hélène Dreyfus
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention, 20, 5, pp. 1032-8
Cancer Epidemiology, Biomarkers and Prevention
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research, 2011, 20, pp.1032-1038
Spurdle, A B, Marquart, L, McGuffog, L, Healey, S, Sinilnikova, O, Wan, F, Chen, X, Beesley, J, Singer, C F, Dressler, A-C, Gschwantler-Kaulich, D, Blum, J L, Tung, N, Weitzel, J, Lynch, H, Garber, J, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Conroy, D, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Selkirk, C G, Daly, M, Isaacs, C, Stoppa-Lyonnet, D, Sinilnikova, O M, Buecher, B, Belotti, M, Mazoyer, S, Barjhoux, L, Verny-Pierre, C, Lasset, C, Dreyfus, H, Pujol, P, Collonge-Rame, M-A, Rookus, M A, Verhoef, S, Kriege, M, Hoogerbrugge, N, Ausems, M G E M, van Os, T A, Thomassen, M & GEMO Study Collaborators 2011, ' Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 20, no. 5, pp. 1032-8 . https://doi.org/10.1158/1055-9965.EPI-10-0909
Spurdle, A B, Marquart, L, McGuffog, L, Healey, S, Sinilnikova, O, Wan, F, Chen, X Q, Beesley, J, Singer, C F, Dressler, A C, Gschwantler-Kaulich, D, Blum, J L, Tung, N, Weitzel, J, Lynch, H, Garber, J, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Conroy, D, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Selkirk, C G, Daly, M, Isaacs, C, Stoppa-Lyonnet, D, Sinilnikova, O M, Buecher, B, Belotti, M, Mazoyer, S, Barjhoux, L, Verny-Pierre, C, Lasset, C, Dreyfus, H, Pujol, P, Collonge-Rame, M A, Rookus, M A, Verhoef, S, Kriege, M, Hoogerbrugge, N, Ausems, M G E M, Os, T A, van Wijnen, J, Devilee, P, Meijers-Heijboer, E J, Blok, M J, Heikkinen, T, Nevanlinna, H, Jakubowska, A, Lubinski, J, Huzarski, T, Byrski, T, Durocher, F, Couch, F J, Lindor, N M, Wang, X S, Thomassen, M, Domchek, S, Nathanson, K, Caligo, M A, Jernstrom, H, Liljegren, A, Ehrencrona, H, For, P K, Ganz, P A, Olopade, O I, Tomlinson, G, Neuhausen, S, Antoniou, A C, Chenevix-Trench, G & Rebbeck, T R 2011, ' Common Genetic Variation at BARD1 Is Not Associated with Breast Cancer Risk in BRCA1 or BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 20, no. 5, pp. 1032-1038 . https://doi.org/10.1158/1055-9965.EPI-10-0909
Cancer epidemiology, biomarkers & prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers and Prevention, 20(5), 1032-1038
Cancer Epidemiology, Biomarkers and Prevention, 2011, 20 (5), pp.1032-1038. ⟨10.1158/1055-9965.EPI-10-0909⟩
Cancer Epidemiology Biomarkers and Prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers & Prevention, 20, 1032-8
Cancer Epidemiology Biomarkers & Prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers and Prevention
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research, 2011, 20, pp.1032-1038
Spurdle, A B, Marquart, L, McGuffog, L, Healey, S, Sinilnikova, O, Wan, F, Chen, X, Beesley, J, Singer, C F, Dressler, A-C, Gschwantler-Kaulich, D, Blum, J L, Tung, N, Weitzel, J, Lynch, H, Garber, J, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Conroy, D, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Selkirk, C G, Daly, M, Isaacs, C, Stoppa-Lyonnet, D, Sinilnikova, O M, Buecher, B, Belotti, M, Mazoyer, S, Barjhoux, L, Verny-Pierre, C, Lasset, C, Dreyfus, H, Pujol, P, Collonge-Rame, M-A, Rookus, M A, Verhoef, S, Kriege, M, Hoogerbrugge, N, Ausems, M G E M, van Os, T A, Thomassen, M & GEMO Study Collaborators 2011, ' Common genetic variation at BARD1 is not associated with breast cancer risk in BRCA1 or BRCA2 mutation carriers ', Cancer Epidemiology, Biomarkers & Prevention, vol. 20, no. 5, pp. 1032-8 . https://doi.org/10.1158/1055-9965.EPI-10-0909
Spurdle, A B, Marquart, L, McGuffog, L, Healey, S, Sinilnikova, O, Wan, F, Chen, X Q, Beesley, J, Singer, C F, Dressler, A C, Gschwantler-Kaulich, D, Blum, J L, Tung, N, Weitzel, J, Lynch, H, Garber, J, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Conroy, D, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Davidson, R, Chu, C, Eccles, D, Selkirk, C G, Daly, M, Isaacs, C, Stoppa-Lyonnet, D, Sinilnikova, O M, Buecher, B, Belotti, M, Mazoyer, S, Barjhoux, L, Verny-Pierre, C, Lasset, C, Dreyfus, H, Pujol, P, Collonge-Rame, M A, Rookus, M A, Verhoef, S, Kriege, M, Hoogerbrugge, N, Ausems, M G E M, Os, T A, van Wijnen, J, Devilee, P, Meijers-Heijboer, E J, Blok, M J, Heikkinen, T, Nevanlinna, H, Jakubowska, A, Lubinski, J, Huzarski, T, Byrski, T, Durocher, F, Couch, F J, Lindor, N M, Wang, X S, Thomassen, M, Domchek, S, Nathanson, K, Caligo, M A, Jernstrom, H, Liljegren, A, Ehrencrona, H, For, P K, Ganz, P A, Olopade, O I, Tomlinson, G, Neuhausen, S, Antoniou, A C, Chenevix-Trench, G & Rebbeck, T R 2011, ' Common Genetic Variation at BARD1 Is Not Associated with Breast Cancer Risk in BRCA1 or BRCA2 Mutation Carriers ', Cancer Epidemiology Biomarkers and Prevention, vol. 20, no. 5, pp. 1032-1038 . https://doi.org/10.1158/1055-9965.EPI-10-0909
Cancer epidemiology, biomarkers & prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers and Prevention, 20(5), 1032-1038
Cancer Epidemiology, Biomarkers and Prevention, 2011, 20 (5), pp.1032-1038. ⟨10.1158/1055-9965.EPI-10-0909⟩
Cancer Epidemiology Biomarkers and Prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Cancer Epidemiology, Biomarkers & Prevention, 20, 1032-8
Cancer Epidemiology Biomarkers & Prevention, 20(5), 1032-1038. American Association for Cancer Research Inc.
Background: Inherited BRCA1 and BRCA2 (BRCA1/2) mutations confer elevated breast cancer risk. Knowledge of factors that can improve breast cancer risk assessment in BRCA1/2 mutation carriers may improve personalized cancer prevention strategies. Meth
Autor:
Sarah Benafif, Ros Eeles, Ian Whitmore, Zsofia Kote-Jarai, Ezequiel Anokian, Clara Cieza-Borrella, Ed Saunders
Publikováno v:
Journal of Clinical Oncology. 36:e13617-e13617
e13617Background: The BARCODE2 study is investigating the response to platinum chemotherapy in men with advanced prostate cancer (PrCa) and a germline mutation in a DNA repair gene. We present the ...
Autor:
Zsofia Kote-Jarai, David V. Conti, Tokhir Dadaev, Ed Saunders, D. Leongamornlert, Ros Eeles, Sarah Wakerell, Clara Cieza Borrella, Mark N. Brook, Artitaya Lophatananon, Kenneth Muir, Ian Whitmore, K. Govindasami
Publikováno v:
Journal of Clinical Oncology. 36:18-18
18 Background: Prostate cancer (PrCa) is the most common solid tumour in men in the Western world. There is substantial evidence that PrCa predisposition is due both to common and rare germline variation. Methods: We screened 167 genes from DNA damag
Autor:
Ruth M. L. Warren, Martin O. Leach, Deborah J. Thompson, Gek Kwan-Lim, Ros Eeles, Fiona J. Gilbert, D. Gareth Evans
Publikováno v:
Radiology. 252:358-368
To review imaging features of screening-detected cancers on images from diagnostic and prior examinations to identify specific abnormalities to aid earlier detection of or facilitate differentiation of cancers in BRCA1 and BRCA2 carriers and in women
Autor:
Shirley Hodgson, Louise Izatt, Richard S. Houlston, Samantha Fisher, Johanne Geary, Ros Eeles, S. J. Payne, Peter Sasieni
Publikováno v:
Familial Cancer. 7:163-172
The family histories of 130 individuals with documented hereditary non-polyposis colorectal cancer (HNPCC) (caused by mutations in mismatch-repair (MMR) genes MSH2 (n = 64), MLH1 (n = 62) or MSH6 (n = 4)) were obtained, and incidence of cancers in th
Autor:
Rachel Palmieri Weber, Paul D.P. Pharoah, Zsofia Kote-Jarai, John S. Witte, Peter M. Scarbrough, Judy Garber, Stephen B. Gruber, Doug Easton, Jennifer A. Doherty, Thomas A. Sellers, Rayjean J. Hung, Yonathan Brhane, Peter Kraft, Christopher I. Amos, Joellen M. Schildkraut, Ros Eeles, Kevin McDonnell, Amit Joshi, Kenneth Muir, David J. Hunter, Brian E. Henderson, Edwin S. Iversen
Publikováno v:
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, vol 25, iss 1
Background: DNA damage is an established mediator of carcinogenesis, although genome-wide association studies (GWAS) have identified few significant loci. This cross-cancer site, pooled analysis was performed to increase the power to detect common va
Autor:
Imogen Locke, Richard D. Williams, Zsofia Kote-Jarai, Susan Shanley, D. Gareth Evans, Mark Girolami, Ros Eeles, Francois Moreews, Diana Eccles, Ana Osorio, Ian Giddings, Lucy Matthews, Colin Campbell
Publikováno v:
Clinical Cancer Research. 12:3896-3901
Purpose: In this study, the differential gene expression changes following radiation-induced DNA damage in healthy cells from BRCA1/BRCA1 mutation carriers have been compared with controls using high-density microarray technology. We aimed to establi
Autor:
Fiona Douglas, Douglas F. Easton, Ros Eeles, Trevor Cole, Russell Davies, Judith Brown, Susan Peock, Iqbal Warsi, Diana Eccles, Shirley Hodgson, Louise Izatt, Margaret Cook, Antonis C. Antoniou, Joan Paterson, D. Gareth Evans, Jenny Mattison, Gillian Mitchell, Ruth Warren, Lucy Burgess
Publikováno v:
Cancer Research. 66:1866-1872
High breast density as measured on mammograms is a strong risk factor for breast cancer in the general population, but its effect in carriers of germline BRCA1 and BRCA2 mutations is unclear. We obtained mammograms from 206 female carriers of BRCA1 o