Zobrazeno 41 - 50
of 138
pro vyhledávání: '"Ronjon Chakraverty"'
Autor:
Ruth Pettengell, Richard E. Clark, Donald Milligan, Michael Roughton, Panagiotis D. Kottaridis, Stephen Mackinnon, Jun Shen, Adele K. Fielding, Emma C. Morris, Kirsty Thomson, John A. Snowden, Peter R. E. Johnson, Adrian Bloor, Guillermo Ortí, Matthew Collin, Anne Parker, Geoff Hale, Ronjon Chakraverty, Charles Crawley, Andrew Clark, Andrew R. Pettitt, Karl S. Peggs
In vivo alemtuzumab reduces the risk of graft-versus-host disease (GVHD) and nonrelapse mortality after reduced intensity allogeneic transplantation. However, it also delays immune reconstitution, leading to frequent infections and potential loss of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33ef220b89e09745074583aea6167412
https://doi.org/10.1182/blood-2010-05-286856
https://doi.org/10.1182/blood-2010-05-286856
Autor:
Alastair, Hotblack, Sara, Seshadri, Lei, Zhang, Sahar, Hamrang-Yousefi, Ronjon, Chakraverty, David, Escors, Clare L, Bennett
Publikováno v:
Molecular Therapy
Recombinant lentiviral vectors (LVs) are highly effective vaccination vehicles that elicit protective T cell immunity in disease models. Dendritic cells (DCs) acquire antigen at sites of vaccination and migrate to draining lymph nodes, where they pri
Autor:
Pedro Santos e Sousa, Claire Winship, Cara Lomas, Thomas Conlan, Clare L. Bennett, Ronjon Chakraverty, Vincent Plagnol, H Shorrock, Terry K. Means, Sophie Ward
Publikováno v:
Biology of Blood and Marrow Transplantation. 22(3)
Publikováno v:
European Journal of Immunology. 41:2530-2534
"Faster, better, more'' is the conventional benchmark used to define responses of memory T cells when compared with their naive counterparts. In this issue of the European Journal of Immunology, Mark and Warren Shlomchik and colleagues [Eur. J. Immun
Autor:
Frederic Geissmann, Ronjon Chakraverty, Thomas Conlan, Terry K. Means, Céline Trouillet, Farnaz Fallah-Arani, Hugh D. Goold, Barry Flutter, Laurent Chorro, Clare L. Bennett
Publikováno v:
Blood
Langerhans cells (LCs) are a distinct population of dendritic cells that form a contiguous network in the epidermis of the skin. Although LCs possess many of the properties of highly proficient dendritic cells, recent studies have indicated that they
Autor:
Ronjon Chakraverty, Stephen Mackinnon
Publikováno v:
Journal of Clinical Oncology. 29:1855-1863
Historically, high levels of treatment-related mortality restricted the use of standard myeloablative allogeneic stem-cell transplantation to a minority of young and fit patients with lymphoma. Over the last decade, increasing numbers of patients wit
Publikováno v:
The Journal of Immunology. 186:4565-4572
Cutaneous vaccination with lentiviral vectors generates systemic CD8 T cell responses that have the potential to eradicate tumors for cancer immunotherapy. However, although s.c. immunization with
Autor:
Panagiotis D. Kottaridis, David C. Linch, Stephen Mackinnon, Irfan Kayani, Anthony H. Goldstone, Adele K. Fielding, Rachael Hough, Ronjon Chakraverty, Karl S. Peggs, Emma C. Morris, Kirsty Thomson, Noha Edwards
Publikováno v:
Journal of Clinical Oncology. 29:971-978
Purpose Reduced-intensity conditioning has minimized nonrelapse-related mortality rates after allogeneic transplantation in patients with Hodgkin's lymphoma, and relapse has now become the major cause for treatment failure. We aimed to assess the imp
Autor:
Ronjon Chakraverty
Publikováno v:
Journal of Clinical Investigation. 124:480-482
Th cells are the major effector cells in transplant rejection and can be divided into Th1, Th2, Th17, and Treg subsets. Th differentiation is controlled by transcription factor expression, which is driven by positive and negative cytokine and chemoki
Autor:
Megan Sykes, Ronjon Chakraverty, Barry Flutter, Clare L. Bennett, Stephen Henderson, Sara Ghorashian, Shivajanani Sivakumaran, Gordon J. Freeman, Jian-Guo Chai, Noha Edwards, Farnaz Fallah-Arani
Publikováno v:
Journal of Clinical Investigation. 120:3855-3868
Allogeneic blood or BM transplantation (BMT) is the most commonly applied form of adoptive cellular therapy for cancer. In this context, the ability of donor T cells to respond to recipient antigens is coopted to generate graft-versus-tumor (GVT) res