Zobrazeno 41 - 50
of 74
pro vyhledávání: '"Renee Whan"'
Autor:
Jennifer Trieu, Andrew J. Gifford, Joshua A. McCarroll, Sharon M. Sagnella, Jennifer A. MacDiarmid, Christopher M. Fife, Renee Whan, David S. Ziegler, Maria Kavallaris, Himanshu Brahmbhatt, Alexander Macmillan
Publikováno v:
Molecular cancer therapeutics. 17(5)
Advanced stage neuroblastoma is an aggressive disease with limited treatment options for patients with drug-resistant tumors. Targeted delivery of chemotherapy for pediatric cancers offers promise to improve treatment efficacy and reduce toxicity ass
Publikováno v:
Scientific Reports
We are literally the stuff from which our tissue fabrics and their fibers are woven and spun. The arrangement of collagen, elastin and other structural proteins in space and time embodies our tissues and organs with amazing resilience and multifuncti
Autor:
Sook Wern Chua, Amadeus Gladbach, Renee Whan, Alexander Macmillan, Michael Kassiou, Mercedes Cueto, Lev Lewis, Inmaculada Vaca, Janet van Eersel, Lars M. Ittner, Alberto Cornejo, Claire H. Stevens
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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In Alzheimer’s disease, the microtubule-associated protein tau forms intracellular neurofibrillary tangles (NFTs). A critical step in the formation of NFTs is the conversion of soluble tau into insoluble filaments. Accordingly, a current therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a6845d59b8d77eb582c41dc82316c5c
http://hdl.handle.net/10261/185311
http://hdl.handle.net/10261/185311
Autor:
May Lim, Renee Whan, William S. Price, Timothy Stait-Gardner, Alexander E. Dunn, Alexander Macmillan, Cyrille Boyer, Douglas J. Dunn
Publikováno v:
Polym. Chem.. 5:3311-3315
P(DEGMA-co-OEGMA-b-[TMSPMA-co-VBA])@silica@magnetite polymer–nanoparticle composites have been developed as a platform for controllable drug release. The nanocomposite facilitates controllable release of therapeutic molecules through breakage of pH
Autor:
Renee Whan, Danielle Froio, Andrew Burgess, Rohit Jain, David Gallego-Ortega, Paul Timpson, Maija R.J. Kohonen-Corish, Pauline Mélénec, Amr H. Allam, Shane T. Grey, Sean C. Warren, Thomas R. Cox, Anthony J. Gill, Amber L. Johns, Anaiis Zaratzian, Jaswinder S. Samra, Celine Heu, Morghan C. Lucas, Tri Giang Phan, Angela Steinmann, Lorraine A. Chantrill, Nathanial L. E. Harris, Alice Boulghourjian, Yingxiao Wang, Adnan Nagrial, Alison Drury, Arne A. S. Adam, Claire Vennin, Owen J. Sansom, Christopher J. Ormandy, Nicola Currey, Marina Pajic, Angela Chou, Michael S. Samuel, Stacey N. Walters, Wolfgang Weninger, T.R. Jeffry Evans, Venessa T. Chin, Kurt I. Anderson, Richard P. Harvey, James R.W. Conway, Andrew V. Biankin, Jennifer P. Morton, Astrid Magenau, Rachael A. McCloy, Ewan J. McGhee, Max Nobis, David Herrmann, Marc Giry-Laterriere, Gonzalo del Monte-Nieto, Mark Pinese
Publikováno v:
Science translational medicine. 9(384)
The emerging standard of care for patients with inoperable pancreatic cancer is a combination of cytotoxic drugs gemcitabine and Abraxane, but patient response remains moderate. Pancreatic cancer development and metastasis occur in complex settings,
Autor:
Nicholas Ariotti, Thomas P. Davis, H. Forgam, Renee Whan, Friederike M. Mansfeld, John F. Quinn, J. McCarroll, Lars Esser, I. Slapetova, Maria Kavallaris
Publikováno v:
ESMO Open. 3:A367-A368
Introduction Medulloblastoma is the most common malignant brain tumour in children. Chemoresistance and treatment toxicity are major problems for this disease. New effective and less toxic therapies are needed. Short-Interfering-RNA’s (siRNA) are g
Autor:
Renee Whan, Lars Esser, Maria Kavallaris, Rafael B. Erlich, Thomas P. Davis, Alexander Macmillan, Johan Sebastian Basuki, Hien Tt Duong, Mia C. Akerfeldt, Cyrille Boyer
Publikováno v:
ACS Nano. 7:10175-10189
We describe the synthesis of iron oxide nanoparticles (IONPs) with excellent colloidal stability in both water and serum, imparted by carefully designed grafted polymer shells. The polymer shells were built with attached aldehyde functionality to ena
Autor:
Eh Hau Pan, Brian S. Hawkett, Renee Whan, Nicole S. Bryce, Nicole W. S. Fong, Binh T. T. Pham, Trevor W. Hambley, Nirmesh Jain
Publikováno v:
Biomater. Sci.. 1:1260-1272
Diffusion of active cytotoxic agents throughout an entire solid tumour is a particular challenge to successful drug delivery. Here we show the simple and robust generation of non-toxic, 10-15 nm superparamagnetic iron oxide nanoparticles (SPIONs) tha
Autor:
Iveta Slapetova, Renee Whan, Rama Addepalli, Martin P. Bucknall, Jayashree Arcot, Simone A. Osborne, Maria V. Chandra-Hioe
Publikováno v:
Food Research International. 53:104-109
Folic acid is the fortificant of choice mainly because of its stability. The mandatory fortification program was implemented based on the evidence that increased intake of folic acid in the periconceptional period reduced the prevalence of neural tub
Autor:
Ralph J. Mobbs, Lies Boelen, Amadeus Gladbach, Ashwin Unnikrishnan, Philip Hardy, William R. Walsh, Jeanette E. Villanueva, Avani Yeola, Louise E. Purton, Vashe Chandrakanthan, Yan Yu, Carl R. Walkley, Shane T. Grey, Alexander Macmillan, John E. Pimanda, Peter Zarzour, Lars M. Ittner, Robyn L. Ward, Qiao Qiao, Andrea Nuñez, Kathy Knezevic, Jair C. Kwan, Young Chan Kang, Luke B. Hesson, Jason W. H. Wong, Cintia Palu, Fabien Delerue, Rabab Nasrallah, Dominik Beck, Michael Carnell, Rema A. Oliver, Renee Whan
Current approaches in tissue engineering are geared toward generating tissue-specific stem cells. Given the complexity and heterogeneity of tissues, this approach has its limitations. An alternate approach is to induce terminally differentiated cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::121c9c15a1ce49b18156ab3905430b9a
https://europepmc.org/articles/PMC4843430/
https://europepmc.org/articles/PMC4843430/