Zobrazeno 51 - 60
of 148
pro vyhledávání: '"Reinaldo N. Takahashi"'
Publikováno v:
Neuroscience Letters. 380:270-275
Δ9-THC and synthetic cannabinoids produce memory impairment in humans as well as in laboratory animals. The high concentration of cannabinoid CB1 receptors and the presence of endocannabinoids in the hippocampus suggest that a cannabinoid neurochemi
Publikováno v:
Neurobiology of Aging. 26:957-964
Caffeine, a non-selective adenosine receptor antagonist, has been suggested as a potential drug to counteract age-related cognitive decline since critical changes in adenosinergic neurotransmission occur with aging. In the present study, olfactory di
Publikováno v:
Life Sciences. 77:693-706
The purpose of the present study was to investigate whether Lewis (LEW) and spontaneously hypertensive rats (SHR), characterized in numerous behavioral tests as strains with high-anxiety and low-anxiety, respectively, could differ in their sensitivit
Publikováno v:
Behavioural Brain Research. 159:197-205
Spontaneously hypertensive rats (SHR) exhibit impairment across several cognitive domains such as attention, short-term memory and spatial reference memory. These cognitive deficits have been variously attributed to disrupted dopaminergic, cholinergi
Publikováno v:
Neuroscience Letters. 376:160-165
The recognition of an unfamiliar juvenile rat by an adult rat has been shown to imply short-term memory processes. The present study was designed to examine the role of adenosine receptors in the short-term social memory of rats using the social reco
Autor:
Alcir Luiz Dafre, Reinaldo N. Takahashi, Patricia S. Brocardo, Ana Lúcia S. Rodrigues, Pablo Pandolfo
Publikováno v:
Toxicology. 207:283-291
This study investigates the effects of acute exposure to organophosphate insecticide malathion (250 mg/kg, i.p.) and/or ZnCl2 (5 mg/kg, i.p.), with the following parameters: lipid peroxidation and the activity of acetylcholinesterase (AChE), glutathi
Publikováno v:
European Journal of Pharmacology. 499:147-154
The anxiolytic property of ethanol is generally accepted to be an important motivational factor for its consumption and the development of alcohol dependence. Recent studies suggest that adenosine receptors mediate important actions of ethanol, such
Publikováno v:
Neuroscience Letters. 349:49-52
The effect of systemic administration of the cannabinoid antagonist SR 141716A (N-(piperidin-1-yl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxyamide) on penile erection and yawning induced by apomorphine was investigated in rats. SR 141716A (2 m
Publikováno v:
Pharmacology Biochemistry and Behavior. 75:763-768
Cannabinoid receptor agonists significantly inhibit nociceptive responses in a large number of animal models. The present study examined whether mice displaying different basal levels of anxiety in the plus-maze test of anxiety might differ in terms
Publikováno v:
European Journal of Pharmacology. 462:115-123
Some human and animal studies have demonstrated enhancement of memory processes when ethanol was administered immediately after training and subjects were later tested in the drug-free state. The aim of this study was to evaluate the effect of acute