Zobrazeno 101 - 110
of 1 460
pro vyhledávání: '"R. Mayeux"'
Publikováno v:
Journal of the American Society of Nephrology : JASN. 18(6)
Acute kidney injury (AKI) remains a frequent and serious complication of human sepsis that contributes significantly to mortality. For better understanding of the development of AKI during sepsis, the cecal ligation and puncture (CLP) murine model of
Autor:
Liping Wu, Philip R. Mayeux
Publikováno v:
The FASEB Journal. 21
Autor:
Wu Liping, Philip R. Mayeux
Publikováno v:
The FASEB Journal. 21
Autor:
Liping Wu, Philip R. Mayeux
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 320(3)
The mortality rate for septic patients with acute renal failure is approximately doubled compared with patients with sepsis alone. Unfortunately, the treatment for sepsis-induced renal failure has advanced little during the last several decades. Beca
Publikováno v:
Molecular and cellular biochemistry. 297(1-2)
Despite the recognized role of bradykinin (BK)-induced calcium and chloride conductance in regulating salt transport in the kidney, the signaling pathway involved has not been well examined. Patch clamp of murine proximal tubule (TKPTS) cells reveale
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 91(2)
Since inducible nitric oxide synthase (iNOS) and proximal tubule injury are known to be critical determinants of lipopolysaccharide (LPS)-induced renal failure, the role of nitric oxide (NO) in proximal tubule cell apoptosis was examined. An 18-h tre
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 315(2)
This study examined the ability of the endocannabinoids 2-arachidonoyl glycerol (2-AG) and noladin ether as well as the synthetic cannabinoid CP-55,940 [(-)- cis -3-[2-hydroxy-4-(1,1-dimethylheptyl)phenyl]- trans -4-(3-hydroxypropyl) cyclohexanol] to
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 314(2)
Noladin ether (NE) is a putative endogenously occurring cannabinoid demonstrating agonist activity at CB1 receptors. Because of reported selective affinity for CB1 receptors, the pharmacological actions of NE at CB2 receptors have not been examined.
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 313(2)
Despite the recognized physiological role of bradykinin (BK) in the kidney in maintaining glomerular and tubule function and its role in pathological states such as endotoxemia, diabetes, and other diseases, relatively little is known about the mecha
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