Zobrazeno 61 - 70
of 108
pro vyhledávání: '"Quansheng Zhou"'
Autor:
Pengda Guo, Gaochuan Zhang, Fazlul H. Sarkar, Zhiwei Wang, Ping Yang, Lucio Miele, Quansheng Zhou
Publikováno v:
Biochimica et biophysica acta. 1836(1)
Robust anaerobic metabolism plays a causative role in the origin of cancer cells; however, the oncogenic metabolic genes, factors, pathways, and networks in genesis of tumor-initiating cells (TICs) have not yet been systematically summarized. In addi
Autor:
Jian Tu, Di Yu, Zhifei Cao, Ping Yang, Pengda Guo, Quansheng Zhou, Shilong Fu, Yanyan Pan, Gaochuan Zhang, Meimei Bao, Bingxue Shang
Publikováno v:
Toxicology letters. 218(2)
Uncontrolled tumor cell proliferation and robust neovascularization are prominent features of aggressive ovarian cancers. Although great efforts in anti-ovarian cancer therapy have been made in the past 4 decades, the 5-year survival rates for ovaria
Autor:
Hongyan Han, Yanyan Pan, Di Yu, Shilong Fu, Ping Yang, Bo Yang, Quansheng Zhou, Meimei Bao, Gaochuan Zhang, Zhifei Cao
Publikováno v:
Toxicology letters. 215(3)
Osteosarcoma is one of the most common malignant bone tumors in children and adolescents. Although extensive efforts have been made in anti-osteosarcoma therapy in recent decades, there are no effective low-toxicity drugs for treating patients with m
Autor:
Ruifang, Liu, Zhifei, Cao, Jian, Tu, Yanyan, Pan, Bingxue, Shang, Gaochuan, Zhang, Meimei, Bao, Shasha, Zhang, Ping, Yang, Quansheng, Zhou
Publikováno v:
Pigment cellmelanoma research. 25(5)
Melanoma cells actively participate in tumor angiogenesis and vasculogenic mimicry. However, anti-angiogenic therapy in patients with melanoma has not shown a significant survival gain. Thus, new anti-melanoma angiogenic and vasculogenic drugs are hi
Publikováno v:
Hybridoma (2005). 31(3)
SZ117 is a monoclonal antibody against matrix metalloproteinase-2 (MMP-2) and exhibits anti-tumor angiogenic effect. In this study, we observed that SZ117 bound to a 280 kDa protein, which was detected in tumor cell-derived Matrigel and various tumor
Autor:
Yanyan Pan, Quansheng Zhou, Yizhong Feng, Bingxue Shang, Pengda Guo, Meimei Bao, Ruifang Liu, Jian Tu, Zhifei Cao, Shasha Zhang
Publikováno v:
Leukemialymphoma. 53(12)
Anti-lymphoma therapy continues to present a major challenge. Even though cytotoxic therapy, immunotherapy and molecularly targeted therapy have been used in the clinic to treat the disease, effective anti-lymphoma drugs are still needed. In this stu
Publikováno v:
Thrombosis and Haemostasis. 71:507-510
SummaryCultured human umbilical vein endothelial cells were incubated with defibrotide at concentrations of 0, 5, 50 and 500 jxg/ml for 4 and 24 h respectively. Thrombomodulin activity and molecules on the surface of the cells were determined by chro
Publikováno v:
Stem cells and development. 21(6)
Induced pluripotent stem cells (iPSCs) have recently boomed enthusiasm in stem cell therapy, whereas high potential tumorigenesis of iPSCs has become the biggest obstacle for clinic application and the tumorigenic genes in iPSCs have not been well do
Publikováno v:
Hybridoma (2005). 31(1)
In this study, using an in vitro tube formation model, we observed that SZ117, a monoclonal antibody against matrix metalloproteinase-2 (MMP2), attenuated a capillary-like tube structure formed by tumor endothelial cell 3B11 and human sarcoma cell MG
Publikováno v:
Frontiers of medicine. 6(1)
Antitumor angiogenic therapy has been shown promising in the treatment of several advanced cancers since the approval of the first antiangiogenic drug Avastin in 2004. Although the current antiangiogenic drugs reduce the density of tumor blood vessel