Zobrazeno 61 - 70
of 432
pro vyhledávání: '"Qing-Yu He"'
Publikováno v:
Analytical Chemistry. 94:3467-3475
Autor:
Qing-Yu He, Shang‐Jia Huang, Jun‐Xiong Chen, Lan Ouyang, Jing Zhang, Li-Ye Zhong, Nan-Nan Yu, Yu‐Long Niu, Yang Wang, Chun-Hua Lu
Publikováno v:
MedComm, Vol 2, Iss 4, Pp 810-820 (2021)
MedComm
MedComm
Lung adenocarcinoma (LAC) is one of the most common pulmonary adenocarcinomas with a high peak of mortality, and metastasis is the main culprit of LAC deaths. microRNAs play important role in cancer metastasis, and thus are regarded as potential diag
Autor:
Shu-Jun Li, Ya-Ping Liu, Qian Zuo, Qing-Yu He, Xing-Feng Yin, Ding-Kang Wang, Zi-Ting Yao, Long Liao, Wen Wen Xu
Publikováno v:
Cancer Letters. 521:281-293
Background Colorectal cancer (CRC) is one of the most malignant cancer worldwide, and the limited efficacy of existing treatments is the leading cause of death in patients with CRC. Thus, novel drugs for CRC treatment are urgently needed. Methods We
A stable reference human transcriptome and proteome as a standard for reproducible omics experiments
Autor:
Shaohua Lu, Hong Lu, Tingkai Zheng, Huiming Yuan, Hongli Du, Youhe Gao, Yongtao Liu, Xuanzhen Pan, Wenlu Zhang, Shuying Fu, Zhenghua Sun, Jingjie Jin, Qing-Yu He, Yang Chen, Gong Zhang
In recent years, the development of high-throughput omics technology has greatly promoted the development of biomedicine. However, the poor reproducibility of omics techniques limits its application. It is necessary to use standard reference material
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::230be379b6e384f911c2c978c48f1192
https://doi.org/10.1101/2022.11.16.516732
https://doi.org/10.1101/2022.11.16.516732
Autor:
Hui-Fang, Hu, Gui-Bin, Gao, Xuan, He, Yu-Ying, Li, Yang-Jia, Li, Bin, Li, YunLong, Pan, Yang, Wang, Qing-Yu, He
Publikováno v:
Journal of Advanced Research.
Acquired resistance to BRAF inhibitor vemurafenib is frequently observed in metastatic colorectal cancer (CRC), and it is a thorny issue that results in treatment failure. As adaptive responses for vemurafenib treatment, a series of cellular bypasses
Publikováno v:
Molecular Biomedicine, Vol 2, Iss 1, Pp 1-15 (2021)
Molecular Biomedicine
Molecular Biomedicine
Post-translational modifications (PTMs) of Cyclin-dependent kinase 5 (CDK5) have emerged as important regulatory mechanisms that modulate cancer development in patients. Though CDK5 is an atypical member of the cyclin-dependent kinase family, its abe
Autor:
Shengrong Li, Pengwei Zhang, Fang Xu, Shengcao Hu, Jiacong Liu, Yi Tan, Zhengchao Tu, Hongyan Sun, Zhi-Min Zhang, Qing-Yu He, Pinghua Sun, Ke Ding, Zhengqiu Li
Publikováno v:
Journal of medicinal chemistry. 65(15)
Covalent inhibitors with an electrophilic warhead have received considerable attention due to their remarkable pharmacological properties. However, the electrophilic warhead in covalent drugs is often an α, β-unsaturated amide, and the targets are
Autor:
Gong Zhang, Xuesong Sun, Songhui Lu, Hualong Wang, Xin Cao, Zhong Guo, Qing-Yu He, Yuelei Dong
Publikováno v:
Journal of Proteome Research. 20:3179-3187
Harmful algal blooms (HABs) are symptomatic of ecosystem imbalance, leading to major worldwide marine natural disasters, and seriously threaten the human health. Some HAB algae's exceptional genome size prohibited the genomic investigations on molecu
Publikováno v:
Journal of Proteome Research. 20:2839-2850
The unreasonable misuse of antibiotics has led to the emergence of large-scale drug-resistant bacteria, seriously threatening human health. Compared with drug-sensitive bacteria, resistant bacteria are difficult to clear by host immunity. To fully ex
Publikováno v:
Journal of Proteome Research. 20:2319-2328
Trans-Cinnamaldehyde (TC) is a widely used food additive, known for its sterilization, disinfection, and antiseptic properties. However, its antibacterial mechanism is not completely understood. In this study, quantitative proteomics was performed to