Zobrazeno 101 - 110
of 142
pro vyhledávání: '"Pietro Mastroeni"'
Autor:
Jacqueline K. White, Jenefer M. Blackwell, Jean François Popoff, Pietro Mastroeni, Carlton A. Evans
Publikováno v:
Journal of leukocyte biology. 77(3)
Solute carrier family 11a member 1 (Slc11a1; formerly natural resistance-associated macrophage protein 1) encodes a late endosomal/lysosomal protein/divalent cation transporter, which regulates iron homeostasis in macrophages. During macrophage activ
Autor:
Tim Raine, Mitchell Kronenberg, Stephane Sidobre, Pietro Mastroeni, Anne Cooke, Paola Zaccone
Publikováno v:
European journal of immunology. 34(11)
Infectious disease has been proposed as an environmental modifier of autoimmunity in both human populations and the NOD mouse. We found that infection of NOD mice with attenuated, but not killed, Salmonella typhimurium can reduce the incidence of typ
Autor:
Tran Tan Khoa, To Song Diep, John Wain, Phillippa L. Connerton, Vo Van Ho, Tran Tinh Hien, Simon Murch, Paul Everest, Jeremy Farrar, Phan Van Be Bay, Gordon Dougan, Christopher M. Parry, Deborah House, Pietro Mastroeni, Nguyen Quoc Chanh, Nicholas J. White
Publikováno v:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 39(1)
One of the most serious complications of typhoid fever is intestinal perforation. Of 27 patients admitted to a provincial hospital in the Mekong Delta region of Vietnam who had gastrointestinal perforation secondary to suspected typhoid fever, 67% we
Successful resolution of infections by intracellular pathogens requires gamma interferon (IFN-γ). DNA vaccines promote T helper 1 (Th1) responses by triggering interleukin-12 (IL-12) release by dendritic cells (DC) through Toll-like receptor 9 (TLR9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0e35f956d2c816a1f115db6c8b09bef
https://europepmc.org/articles/PMC470645/
https://europepmc.org/articles/PMC470645/
Autor:
Pietro Mastroeni, Mark Sheppard
Publikováno v:
Microbes and infection. 6(4)
The mouse model is widely used to study the mechanisms of the pathogenesis of, and immunity to, systemic salmonellosis. During infection, Salmonella grows in phagocytic cells that reside in well-defined pathological lesions, are activated by cytokine
Publikováno v:
Infection and immunity. 71(12)
Salmonella infections are still a serious health problem worldwide. Infection of mice with Salmonella enterica serovar Typhimurium results in a systemic infection that closely resembles human typhoid fever caused by the related S. enterica serovar Ty
Autor:
Robert D. Goldin, Simon Clare, Christine Hale, Cameron P. Simmons, Gordon Dougan, Pietro Mastroeni, Richard Aspinall
Publikováno v:
Infection and Immunity. 71(10)
This study investigated the role of intracellular adhesion molecule 1 (ICAM-1) during Salmonella enterica serovar Typhimurium infection of mice. We show that ICAM-1 is expressed in and around granulomas on day 4 of infection in wild-type mice. Howeve
Autor:
Victoria Mallows, Duncan J. Maskell, Pietro Mastroeni, Cerian R. Webb, Fred Heath, Mark Sheppard, Romina Emilianus
Publikováno v:
Cellular microbiology. 5(9)
Salmonella enterica causes severe systemic diseases in humans and animals and grows intracellularly within discrete tissue foci that become pathological lesions. Because of its lifestyle Salmonella is a superb model for studying the in vivo dynamics
Publikováno v:
Expert review of vaccines. 1(4)
For more than a century, bacteria and bacterial products have been used for the treatment of cancer. Starting from the practical observation of tumor regression in individuals with concomitant bacterial infection, the field has evolved into some stan
Autor:
Pietro Mastroeni, Julie A. Musson, C E Hormaeche, Graham S, John H. Robinson, M Mutunga, Khan Cm, De Hormaeche Rd
Publikováno v:
Vaccine. 22(29-30)
Salmonella live vaccine strains harbouring mutations in htrA , a stress protein gene, display increased susceptibility to oxidative stress in vitro. This is believed to be connected to their reduced virulence, perhaps due to impaired survival inside