Zobrazeno 31 - 40
of 117
pro vyhledávání: '"Peter D. Sun"'
Autor:
Angela M, Thornton, Jinghua, Lu, Patricia E, Korty, Yong Chan, Kim, Craig, Martens, Peter D, Sun, Ethan M, Shevach
Publikováno v:
European journal of immunology. 49(3)
The transcription factor Helios is expressed in a large subset of Foxp3(+) Tregs. We previously proposed that Helios is a marker of thymic derived Treg (tTreg), while Helios(−) Treg were induced from Foxp3(−) T conventional (Tconv) cells in the p
Autor:
Malcolm J. W. Sim, Peter D. Sun
Publikováno v:
Immunity. 46:972-974
HLA-F, a non-classical MHC molecule, is not known to present peptides. Dulberger et al. (2017) show that HLA-F contains a distinct peptide-binding groove and can present a diverse array of peptides. LIR1, however, recognized HLA-F away from bound pep
Autor:
Susan Moir, Lela Kardava, Peter D. Sun, Yuxing Li, J. Shawn Justement, Kathleen R. Gittens, Wei Wang, Richard Kwan, Valerie A. Melson, Gwynne Roth, Marissa A. Hand, James W. Austin, Clarisa M. Buckner, Haewon Sohn, Christine Youn, Michael C. Sneller, Tae-Wook Chun, Susan K. Pierce
Immunoglobulin G3 (IgG3) has an uncertain role in the response to infection with and vaccination against human immunodeficiency virus (HIV). Here we describe a regulatory role for IgG3 in dampening the immune system–activating effects of chronic HI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21c81c6c580eff8d7fb3ea246a8eeb8b
https://europepmc.org/articles/PMC6289069/
https://europepmc.org/articles/PMC6289069/
Publikováno v:
Proceedings of the National Academy of Sciences. 112:833-838
Fc gamma receptor I (FcγRI) contributes to protective immunity against bacterial infections, but exacerbates certain autoimmune diseases. The sole high-affinity IgG receptor, FcγRI plays a significant role in immunotherapy. To elucidate the molecul
Autor:
Kate M. Rahbari, Haley A. Brown, Peter D. Sun, Genevieve Holzapfel, Joanna Ireland, Zhongcheng Zou, Sarek A. Shen, Gwynne Roth
Publikováno v:
Protein Expression and Purification. 105:8-13
We have previously developed a glutamine synthetase (GS)-based mammalian recombinant protein expression system that is capable of producing 5–30 mg/L recombinant proteins. The over expression is based on multiple rounds of target gene amplification
Autor:
Nir Friedman, Tomer Arnon, Alfred Singer, Irun R. Cohen, François Van Laethem, Peter D. Sun, Asaf Madi, Erez Greenstein, Irena Zaretsky, Shlomit Reich-Zeliger, Jinghua Lu, Eric Shifrut, Asaf Poran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2def802ae258300256d12a94f887d82a
https://doi.org/10.7554/elife.22057.030
https://doi.org/10.7554/elife.22057.030
Autor:
Peter D. Sun, Polly Matzinger, Sergei Radaev, Nevil J. Singh, Hidde L. Ploegh, Eric Spooner, Kaveh Abdi, Larry M. Lantz, Benedikt M. Kessler, Tsan Sam Xiao
Publikováno v:
The Journal of Immunology. 192:6028-6036
IL-12p40 partners with the p35 and p19 polypeptides to generate the heterodimeric cytokines IL-12 and IL-23, respectively. These cytokines play critical and distinct roles in host defense. The assembly of these heterodimers is thought to take place w
Autor:
Carolyn Mold, Kristopher D. Marjon, Terry W. Du Clos, Lorraine L. Marnell, Jinghua Lu, Peter D. Sun
Publikováno v:
Protein Science. 23:378-386
The pentraxins, C-reactive protein (CRP), and serum amyloid P component (SAP) have previously been shown to function as innate opsonins through interactions with Fcγ receptors. The molecular details of these interactions were elucidated by the cryst
Autor:
Peter D. Sun, Jinghua Lu, Irena Zaretsky, Irun R. Cohen, Alfred Singer, Erez Greenstein, François Van Laethem, Asaf Madi, Nir Friedman, Eric Shifrut, Asaf Poran, Shlomit Reich-Zeliger, Tomer Arnon
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
Diversity of T cell receptor (TCR) repertoires, generated by somatic DNA rearrangements, is central to immune system function. However, the level of sequence similarity of TCR repertoires within and between species has not been characterized. Using n
Publikováno v:
Immunological Reviews. 250:230-238
Pentraxins are a family of secreted pattern recognition proteins containing a homologous pentraxin (PTX) domain of approximately 200 amino acids (Fig. 1). Members of the family, such as C-reactive protein (CRP) (also called PTX1) and serum amyloid P