Zobrazeno 11 - 20
of 117
pro vyhledávání: '"Peter D. Sun"'
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
C-reactive protein (CRP) is a member of the pentraxin family of proteins. These proteins are highly conserved over the course of evolution being present as far back as 250 million years ago. Mammalian pentraxins are characterized by the presence of f
Externí odkaz:
https://doaj.org/article/2334942ac6e94145b3377d7e01f665d8
Autor:
Malcolm J. W. Sim, Paul Brennan, Katherine L. Wahl, Jinghua Lu, Sumati Rajagopalan, Peter D. Sun, Eric O. Long
SummaryGenetic studies associate killer-cell immunoglobulin-like receptors (KIR) and their HLA class I ligands with a variety of human diseases. The basis for these associations, and the relative contribution of inhibitory and activating KIR to NK ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d827f88cf384cacca04290523917c8c6
https://doi.org/10.1101/2023.02.06.527249
https://doi.org/10.1101/2023.02.06.527249
Publikováno v:
eLife. 11
Dimorphic residues at positions 77 and 80 delineate HLA-C allotypes into two groups, C1 and C2, which associate with disease through interactions with C1 and C2-specific natural killer cell receptors. How the C1/C2 dimorphism affects T cell recogniti
Publikováno v:
Protein Expr Purif
To generate stable cell lines that express high levels of recombinant genes often requires screening of a large number of transfected cells using ELISA. The most widely used alternative to ELISA screening is to use an intracellularly expressed GFP re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d4edcbee0cd56fe0aaac5b2e94fd39
https://europepmc.org/articles/PMC8864769/
https://europepmc.org/articles/PMC8864769/
Autor:
Biao He, Zhongcheng Zou, Joanna Ireland, Gwynne Roth, Peter D. Sun, Jason Segura, Thomas C. Shen
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
HIV envelope glycoprotein is the most heavily glycosylated viral protein complex identified with over 20 glycans on its surface. This glycan canopy is thought to primarily shield the virus from host immune recognition as glycans are poor immunogens i
Publikováno v:
Protein Expression and Purification
Due to the important pathological roles of the HIV-1 gp120, the protein has been intensively used in the research of HIV. However, recombinant gp120 preparation has proven to be difficult because of extremely low expression levels. In order to facili
Autor:
Michael Chambers, Safiatou Doumbo, Sarah F. Andrews, Peter D. Crompton, Peter D. Sun, Eric O. Long, Shanping Li, Mary E. Peterson, Richard A. Koup, Boubacar Traore, Kristin L. Boswell, Adrian B. McDermott, Joshua Tan, Aissata Ongoiba, Kassoum Kayentao, Jinghua Lu, Kazutoyo Miura, Christopher M. Tipton, Ababacar Diouf, Carole A. Long, Padmapriya Sekar, Christine S. Hopp, Silvia Portugal, Jeff Skinner
Publikováno v:
The Journal of Experimental Medicine
The role of IgM in human malaria is unclear. In a cohort study in Mali, Hopp et al. find that malaria-specific memory B cells are disproportionally IgM in children, are activated during acute malaria, and produce IgM that inhibits malaria parasite gr
Autor:
Jinghua Lu, Peter D. Sun
Publikováno v:
Journal of Biological Chemistry
bioRxiv
The Journal of Biological Chemistry
bioRxiv
The Journal of Biological Chemistry
A novel coronavirus (SARS-CoV-2) has emerged to a global pandemic and caused significant damages to public health. Human angiotensin-converting enzyme 2(ACE2) was identified as the entry receptor for SARS-CoV-2. As a carboxypeptidase, ACE2 cleaves ma
Autor:
Terry I. Guinter, Mirelle Rojano, Britta Engelhardt, Ingrid Saba, James Chih-Hsin Yang, Abhisek Bhattacharya, Jinghua Lu, Ken-ichi Hanada, Amala Alag, Alfred Singer, François Van Laethem, Peter D. Sun, Jennifer M. Ashe, Xuguang Tai
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Van Laethem, François; Saba, Ingrid; Lu, Jinghua; Bhattacharya, Abhisek; Tai, Xuguang; Guinter, Terry I; Engelhardt, Britta; Alag, Amala; Rojano, Mirelle; Ashe, Jennifer M; Hanada, Ken-Ichi; Yang, James C; Sun, Peter D; Singer, Alfred (2020). Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus. Frontiers in immunology, 11, p. 1216. Frontiers Research Foundation 10.3389/fimmu.2020.01216
Frontiers in Immunology, Vol 11 (2020)
Van Laethem, François; Saba, Ingrid; Lu, Jinghua; Bhattacharya, Abhisek; Tai, Xuguang; Guinter, Terry I; Engelhardt, Britta; Alag, Amala; Rojano, Mirelle; Ashe, Jennifer M; Hanada, Ken-Ichi; Yang, James C; Sun, Peter D; Singer, Alfred (2020). Novel MHC-Independent αβTCRs Specific for CD48, CD102, and CD155 Self-Proteins and Their Selection in the Thymus. Frontiers in immunology, 11, p. 1216. Frontiers Research Foundation 10.3389/fimmu.2020.01216
MHC-independent αβTCRs (TCRs) recognize conformational epitopes on native self-proteins and arise in mice lacking both MHC and CD4/CD8 coreceptor proteins. Although naturally generated in the thymus, these TCRs resemble re-engineered therapeutic ch