Zobrazeno 81 - 90
of 399
pro vyhledávání: '"Pavel Vodicka"'
Autor:
Ludmila Vodickova, Veronika Vymetalkova, Miguel Inacio da Silva Filho, Asta Försti, Christoph Frank, Katerina Jiraskova, Calogerina Catalano, Alessio Naccarati, Vaclav Liska, Miroslav Levy, Pavel Vodicka, Shun Lu, Alexander N.R. Weber, Kari Hemminki, Ondrej Vycital
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1473-1484 (2020)
Cancer Medicine
Cancer Medicine
Objective The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in thes
Autor:
Jirong Long, Anna H. Wu, Min-Ho Shin, Tabitha A. Harrison, Kenneth Offit, Ulrike Peters, Yoon-Ok Ahn, Fränzel J.B. Van Duijnhoven, Jochen Hampe, Qiuyin Cai, Stephanie J. Weinstein, Annika Lindblom, Zhi Zhong Pan, Keum Ji Jung, Chizu Tanikawa, Wanqing Wen, Andrew T. Chan, Wei Hua Jia, Yu-Tang Gao, Isao Oze, Keitaro Matsuo, Zefang Ren, Sun-Seog Kweon, Paul D.P. Pharoah, Victor Moreno, Pavel Vodicka, Yong-Bing Xiang, Jeroen R. Huyghe, Aesun Shin, Dong Hyun Kim, Sun Ha Jee, Koichi Matsuda, Jae Hwan Oh, Andrea Gsur, Yi Xin Zeng, Yingchang Lu, Nan Wang, Jiajun Shi, Wei Zheng, Bethany Van Guelpen, Loic Le Marchand, Li Li, Honglan Li, Jeongseon Kim, Alicja Wolk, Xingyi Guo, Polly A. Newcomb, Yoichiro Kamatani, Li Hsu, Jing Gao, Xiao-Ou Shu, Bingshan Li
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Background: Risk variants identified so far for colorectal cancer explain only a small proportion of familial risk of this cancer, particularly in Asians. Methods: We performed a genome-wide association study (GWAS) of colorectal cancer in East Asian
Autor:
Simona Susova, Linda Bartu, Jan Kral, Pavel Soucek, Rajesh Kumar, Ludmila Vodickova, Miroslav Levy, Tomas Buchler, Fabio Rosa, Petra Bendova, Veronika Vymetalkova, Pavel Vodicka, David J. Hughes, Alessio Naccarati, Barbara Pardini
Publikováno v:
Mutagenesis. 35:273-281
The chemotherapeutic efficacy in colorectal cancer (CRC) is limited due to the inter-individual variability in drug response and the development of tumour resistance. ATP-binding cassette (ABC) transporters are crucial in the development of resistanc
Autor:
Alicja Wolk, Edward Giovannucci, Li Li, Polly A. Newcomb, Kenneth Offit, Clemens Schafmayer, Vicente Martín, Sergi Castellví-Bel, Daniel D. Buchanan, Mingyang Song, Qianchuan He, Martha L. Slattery, Volker Arndt, Anna H. Wu, Amit Joshi, David A. Drew, D. Timothy Bishop, Annika Lindblom, Temitope O. Keku, Jochen Hampe, Ozan Dikilitas, Douglas A. Corley, John B. Harley, Hakon Hakonarson, Steven Gallinger, Noralane M. Lindor, Ian B. Stanaway, Jeffrey K. Lee, Sonja I. Berndt, Veronika Vymetalkova, Syed H.E. Zaidi, Jessica Minnier, Daniel J. Schaid, Ludmila Vodickova, John D. Potter, Heather Hampel, Christopher I. Li, Frank D. Mentch, Wei-Qi Wei, Cornelia M. Ulrich, Marc J. Gunter, Robert E. Schoen, Catherine M. Tangen, Victor Moreno, Shuji Ogino, Tabitha A. Harrison, Albert de la Chapelle, Pavel Vodicka, Andrew T. Chan, Keith R. Curtis, Elisabeth A. Rosenthal, Jenny Chang-Claude, David C. Muller, Paul D.P. Pharoah, Roger L. Milne, David Duggan, Eric B. Larson, David R. Crosslin, Andrea Gsur, Stéphane Bézieau, Graham G. Giles, Robert J. MacInnis, Bahram Namjou, Christopher H. Dampier, Gail P. Jarvik, Andrea N. Burnett-Hartman, Richard B. Hayes, Fränzel J.B. Van Duijnhoven, Wendy K. Chung, Michael Hoffmeister, Mark A. Jenkins, Mathieu Lemire, Thomas J. Hudson, Elizabeth A. Platz, Neil Murphy, Graham Casey, Michael O. Woods, Aung Ko Win, Flora Qu, Li Hsu, Emily White, Peter T. Campbell, Lori C. Sakoda, Jane C. Figueiredo, Minta Thomas, Jeroen R. Huyghe, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Corinne E. Joshu, Yu Ru Su, Ulrike Peters, Stephen B. Gruber, Demetrius Albanes, Stephen N. Thibodeau, Antoni Castells, Hermann Brenner
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if
Autor:
Pavel Vodicka, Barbara Pardini, Szimonetta Turoczi, Antonio Francavilla, Sonia Tarallo, Alessio Naccarati
Publikováno v:
Mutagenesis. 35:243-260
The circulating human transcriptome, which includes both coding and non-coding RNA (ncRNA) molecules, represents a rich source of potential biomarkers for colorectal cancer (CRC) that has only recently been explored. In particular, the release of RNA
Publikováno v:
Pharmacogenomics. 20:1225-1233
DNA repair, a complex biological process, ensures genomic integrity. Alterations in DNA repair, occurring in many cancers, contribute to the accumulation of mutations in the genome, resulting in genomic instability and cancer progression. DNA repair
Publikováno v:
Molecular Aspects of Medicine. 69:73-92
Colorectal carcinogenesis is a multistep process involving the accumulation of genetic alterations over time that ultimately leads to disease progression and metastasis. Binding of transcription factors to gene promoter regions alone cannot explain t
Autor:
Alena Opattova, Sabine A.S. Langie, Mirta Milic, Andrew Collins, Asgeir Brevik, Erdem Coskun, Maria Dusinska, Isabel Gaivão, Ela Kadioglu, Blanca Laffon, Ricard Marcos, Susana Pastor, Jana Slyskova, Bozena Smolkova, Zsófia Szilágyi, Vanessa Valdiglesias, Pavel Vodicka, Katarina Volkovova, Stefano Bonassi, Roger W.L. Godschalk
Publikováno v:
Mutation Research. Genetic Toxicology and Environmental Mutagenesis
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 876-877:503447. Elsevier
Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 876-877:503447. Elsevier
Levels of DNA damage represent the dynamics between damage formation and removal. Therefore, to better interpret human biomonitoring studies with DNA damage endpoints, an individual's ability to recognize and properly remove DNA damage should be char
Autor:
Pavol Makovický, Jiří Dvořák, Miroslav Levý, Peter Makovický, Pavel Rossmann, Lucie Kubínová, Fabian Caja, Pavel Soucek, Luca Vannucci, Dmitry Stakheev, R. Štěpánková, Oleksandr Chernyavskiy, Jiří Křížan, Ludmila Vodickova, Veronika Vymetalkova, Pavel Vodicka
Publikováno v:
Cancers
Volume 13
Issue 10
Cancers, Vol 13, Iss 2463, p 2463 (2021)
Volume 13
Issue 10
Cancers, Vol 13, Iss 2463, p 2463 (2021)
Simple Summary Chronic colitis and colon cancer develop for alteration of the mucosa homeostatic regulation, also involving TGF-β1. Dextran sulphate sodium (DSS)-induced colitis and azoxymethane (AOM)-induced colorectal carcinogenesis animal models
Autor:
Anna Siskova, Veronika Vymetalkova, Pavel Vodicka, Giulio Ferrero, Alessio Naccarati, Chuanpit Hampel, Regine Schneider-Stock
Publikováno v:
Cancer Research. 82:3368-3368
A colorectal adenoma, an aberrantly growing tissue that arises from the intestinal epithelium is considered a precursor of colorectal cancer, the third most common cancer worldwide. In the presented study, we performed a whole transcriptome analysis