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pro vyhledávání: '"Paul A. Trainor"'
Autor:
Paul A. Trainor
What is Developmental Biology? Developmental Biology is a discipline that evolved from the collective fields of embryology, morphology, and anatomy, which firmly established that structure underpins function. In its simplest terms, Developmental Biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3f8dd07d2e778747dfd7a3f1ed9e01b
https://doi.org/10.1016/bs.ctdb.2015.11.029
https://doi.org/10.1016/bs.ctdb.2015.11.029
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:198-205
Retinoic acid (RA) is the active metabolite of vitamin A (retinol) that controls growth and development. The first step of RA synthesis is controlled by enzymes of the alcohol dehydrogenase (ADH) and retinol dehydrogenase (RDH) families that catalyze
Autor:
Gwenn-Aël Carré, Marianna Tedesco, Nick Warr, Angel R. Nebreda, Paul A. Trainor, Madeleine Pope, Sara Wells, Melissa Childers, Ivan del Barco Barrantes, Andy Greenfield, Pam Siggers, Rachel Brixey, Debora Bogani, Cheryl L. Scudamore, Jessica Vitos Faleato
Publikováno v:
Developmental Cell
Summary Loss of the kinase MAP3K4 causes mouse embryonic gonadal sex reversal due to reduced expression of the testis-determining gene, Sry. However, because of widespread expression of MAP3K4, the cellular basis of this misregulation was unclear. He
Autor:
Paul A. Trainor, Raul E. Diaz
Publikováno v:
BMC Evolutionary Biology
BackgroundOne of the most distinctive traits found within Chamaeleonidae is their split/cleft autopodia and the simplified and divergent morphology of the mesopodial skeleton. These anatomical characteristics have facilitated the adaptive radiation o
Publikováno v:
Developmental Biology. 344:941-947
Neurulation, the process of neural tube formation, is a complex morphogenetic event. In the mammalian embryo, an understanding of the dynamic nature of neurulation has been hampered due to its in utero development. Here we use laser point scanning co
Publikováno v:
Development. 136:2329-2334
Obtaining the diversity of interneuron subtypes in their appropriate numbers requires the orchestrated integration of progenitor proliferation with the regulation of differentiation. Here we demonstrate through loss-of-function studies in mice that t
Publikováno v:
Development. 135:729-741
Neurogenesis requires the coordination of neural progenitor proliferation and differentiation with cell-cycle regulation. However, the mechanisms coordinating these distinct cellular activities are poorly understood. Here we demonstrate for the first
Autor:
Lacey R. Ellington, Paul A. Trainor, Karin Gaudenz, Megan L. Lynn, Chunying Du, Natalie Carmaline Jones, Earl F. Glynn, Jean-Phillipe Rey, Jill Dixon, Michael J. Dixon, Kazushi Aoto, Daisuke Sakai
Publikováno v:
Nature Medicine. 14:125-133
Treacher Collins syndrome (TCS) is a congenital disorder of craniofacial development arising from mutations in TCOF1, which encodes the nucleolar phosphoprotein Treacle. Haploinsufficiency of Tcof1 perturbs mature ribosome biogenesis, resulting in st
Publikováno v:
Orthodontics & Craniofacial Research. 10:88-95
Treacher Collins syndrome (TCS) is an autosomal dominant disorder of craniofacial development which results from loss-of-function mutations in the gene TCOF1. TCOF1 encodes the nucleolar phosphoprotein, Treacle, which plays a key role in pre-ribosoma