Zobrazeno 51 - 60
of 130
pro vyhledávání: '"Pankaj Vats"'
Autor:
Gavin Ha, Roman Gulati, Jonathan Reichel, Pankaj Vats, Andrew J. Armstrong, Colin C. Pritchard, Arul M. Chinnaiyan, Vaibhav G. Patel, Rana R. McKay, Anna C. H. Hoge, Ajjai Alva, William Oh, R. Bruce Montgomery, Deepak Kilari, Landon C. Brown, Michael T. Schweizer, Tanya B. Dorff
Publikováno v:
JCO Precis Oncol
PURPOSE Translational studies have shown that CDK12 mutations may delineate an immunoresponsive subgroup of prostate cancer, characterized by high neo-antigen burden. Given that these mutations may define a clinically distinct subgroup, we sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5753fd80165dc1328ffe28ce5f2d4a
https://europepmc.org/articles/PMC7363399/
https://europepmc.org/articles/PMC7363399/
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2079
RNA-seq provides an efficient and sensitive methodology to identify fusion transcripts in cancer tissues. Chimeric reads mapping across two different genes represent potential gene fusions. Various methodologies have been implemented in the detection
Publikováno v:
Methods in Molecular Biology ISBN: 9781493999033
RNA-seq provides an efficient and sensitive methodology to identify fusion transcripts in cancer tissues. Chimeric reads mapping across two different genes represent potential gene fusions. Various methodologies have been implemented in the detection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6aafc25bb4d3c2ae9de1a6af24fac07b
https://doi.org/10.1007/978-1-4939-9904-0_5
https://doi.org/10.1007/978-1-4939-9904-0_5
Autor:
Lisha Wang, Pankaj Vats, Saravana M. Dhanasekaran, Fengyun Su, Jin Chen, Pedram Argani, Thomas J. Giordano, Rahul Mannan, Arul M. Chinnaiyan, Xiaoming Wang, Sathiya Pandi Narayanan, Rohit Mehra, Stephanie L. Skala, Xuhong Cao, Marcin Cieślik, Yuping Zhang, Javed Siddiqui
Publikováno v:
European urology. 78(1)
Background Renal cell carcinomas (RCCs) are a heterogeneous group of neoplasms. Recent sequencing studies revealed various molecular features associated with histologic RCC subtypes, including chromophobe renal cell carcinoma (ChRCC). Objective To ch
Autor:
Pankaj Vats, Monika L. Burness, Arul M. Chinnaiyan, Erin F. Cobain, Robert J. Lonigro, Chandan Kumar-Sinha, Anne F. Schott, Aki Morikawa, Daniel F. Hayes, Robinson, Erica Rabban, C. Van Poznak, Max S. Wicha, Y-M Wu, Jeffrey B. Smerage, Jennifer J. Griggs
Publikováno v:
Cancer Research. 78:P2-09
Background: Immune checkpoint blockade (ICB) is effective in the treatment of various malignancies. Thus far, however, results in breast cancer have been mixed. Elevated tumor mutational load, and subsequent increased likelihood of forming immunogeni
Publikováno v:
Indian J Otolaryngol Head Neck Surg
Concurrent chemoradiation (CCRT) is the mainstay of treatment for majority of locally advanced head and neck carcinomas (LAHNC). Addition of chemotherapy to radiotherapy increases the probability of local control and improved disease-free survival bu
Autor:
Ankit Sethia, Erin L. Crowgey, Todd E. Druley, Gary Burnett, Timothy Harkins, Karl Franke, Pankaj Vats
Publikováno v:
Cancer Research. 81:165-165
Introduction: The evolution of precision oncology will demand the integration of multi-omics, clinical data, demographics and outcomes, which is a complex and computationally intensive endeavor. Accurate and robust molecular characterization of pedia
Autor:
Pankaj Vats, Alyssa Paul, Yoshie Umemura, Timothy F. Cloughesy, Chase Thomas, Nicole Shonka, Daniel Martinez, Isabel Arrillaga-Romany, Ian Wolfe, Benjamin M. Ellingson, Arul M. Chinnaiyan, Evan Cantor, Zachary Miklja, John de Groot, Abed Rahman Kawakibi, Andrew S. Chi, Chandan Kumar-Sinha, Rebecca Harrison, Adam C. Resnick, Nicholas Butowski, Guangrong Lu, Minesh P. Mehta, Joshua E. Allen, Ashley Sumrall, Matthew Hall, Rajen Mody, Carl Koschmann, Mariella G. Filbin, Ruby Siada, Sylvia Kurz, Rohinton Tarapore, Sebastian M Waszak, Doured Daghistani, Hugh J. L. Garton, Viveka Nand Yadav, Javad Nazarian, Amy K. Bruzek, Patrick Y. Wen, Sabine Mueller, Tracy T. Batchelor, Sharon Gardner, Jessica R. Cummings, Sriram Venneti, Jonathan Schwartz, Brendan Mullan, Patricia L. Robertson, Li Jiang, Andrea Franson, Yazmin Odia, Rodrigo Cartaxo
Publikováno v:
Neuro Oncol
Patients with diffuse midline glioma (DMG) harboring H3 K27M mutation rarely survive longer than two years and have no proven therapies following first-line radiation. ONC201, a bitopic DRD2 antagonist and allosteric ClpP agonist, has shown encouragi
Autor:
Tara Skelly, Wen Jiang, Zhen Zhang, Anupriya Agarwal, Amy M. Perou, Olga Potapova, Christopher R. Kinsinger, Matthew A. Wyczalkowski, David J. Clark, Shuang Cai, Felipe da Veiga Leprevost, Linda Hannick, Chen Huang, Paul D. Piehowski, John McGee, Marcin J. Domagalski, Dmitris Placantonakis, Jianbo Pan, Dana R. Valley, Zhiao Shi, Hui Yin Chang, Karen A. Ketchum, Charles A. Goldthwaite, Małgorzata Wierzbicka, Karsten Krug, Yvonne Shutack, Sara R. Savage, Matthew L. Anderson, Alyssa Charamut, Chandan Kumar-Sinha, Sanford P. Markey, Ratna R. Thangudu, Weiping Ma, Oliver F. Bathe, Antonio Colaprico, Yuxing Liao, Eric E. Schadt, Tomasz Czernicki, Seungyeul Yoo, Xi Chen, Stacey Gabriel, Karl R. Clauser, Daniel C. Rohrer, Uma Borate, Uma Velvulou, Larisa Polonskaya, M. Harry Kane, Dmitry M. Avtonomov, Boris Reva, Jacob J. Day, Barbara Hindenach, Matthew J. Ellis, Katherine A. Hoadley, Emek Demir, Rebecca I. Montgomery, Ewa P. Malc, Fengchao Yu, Lijun Yao, Maciej Wiznerowicz, Annette Marrero-Oliveras, Wojciech Szopa, Sailaja Mareedu, Galen Hostetter, Liqun Qi, Hui Zhang, Yige Wu, David N. Hayes, Shankha Satpathy, Corbin D. Jones, Michael J. Birrer, Xinpei Yi, Nathan Edwards, Fei Ding, Jiang Qian, Ning Qu, Alicia Francis, Daniel Cui Zhou, Jakub Stawicki, Bing Zhang, Rodrigo Vargas Eguez, Tao Liu, Dave Tabor, Maureen Dyer, Brian J. Druker, Gilbert S. Omenn, Azra Krek, Meenakshi Anurag, Melissa Borucki, Mathangi Thiagarajan, Shirley Tsang, Shakti Ramkissoon, Alexey I. Nesvizhskii, Li Ding, Lyubomir Valkov Vasilev, Yifat Geffen, James Suh, Tatiana S. Ermakova, Kakhaber Zaalishvili, Adel K. El-Naggar, Ki Sung Um, Ana I. Robles, Wen-Wei Liang, Richard D. Smith, Pei Wang, Emily S. Boja, Anna Calinawan, Yingwei Hu, Jiayi Ji, Renata Ferrarotto, Hongwei Liu, Jonathan T. Lei, Ramani B. Kothadia, Yize Li, Chelsea J. Newton, Anna Malovannaya, Steven A. Carr, Sandra Cerda, Yuriy Zakhartsev, Stephanie De Young, Eric J. Jaehnig, Peter B. McGarvey, Yan Shi, David I. Heiman, Joseph C. Dort, Karin D. Rodland, Lili Blumenberg, Michael A. Gillette, Piotr A. Mieczkowski, Pankaj Vats, Chet Birger, Yongchao Dou, David Fenyö, Saravana M. Dhanasekaran, Pushpa Hariharan, Eunkyung An, Jeffrey R. Whiteaker, George Miles, Jan Lubinski, Shayan C. Avanessian, Samuel H. Payne, Amanda G. Paulovich, Dmitry Rykunov, Lyudmila Petrenko, Martin Hyrcza, Guo Ci Teo, Alissa M. Weaver, D. R. Mani, Houston Culpepper, Meghan C. Burke, Daniel W. Chan, Bo Wen, Nicollette Maunganidze, Elie Traer, Darlene Tansil, Simona Migliozzi, Luciano Garofano, Qing Kay Li, Donghui Tan, Lori J. Sokoll, Mehdi Mesri, Karna Robinson, Fulvio D'Angelo, Kimberly Elburn, Alexander R. Pico, Umut Ozbek, Michael Schnaubelt, Gad Getz, Francesca Petralia, Andrew G. Sikora, Kai Li, Elena V. Ponomareva, Arul M. Chinnaiyan, Robert Zelt, Jun Zhu, Midie Xu, Dimitar Dimitrov Pazardzhikliev, Negin Vatanian, Grace Zhao, Thomas F. Westbrook, Kyung-Cho Cho, Yuefan Wang, Jason E. McDermott, Jeffrey W. Tyner, William Bocik, Shilpi Singh, Stephen E. Stein, Nancy Roche, Alicia Karz, Shannon Richey, Tara Hiltke, Michael Vernon, Lijun Chen, Henry Rodriguez, Xiaoyu Song, Elizabeth R. Duffy, Lin S. Chen, Liwei Cao, Shrabanti Chowdhury, Marcin Cieślik, Michael C. Wendl, Scott D. Jewell, Cristina E. Tognon
Publikováno v:
Cancer Cell
We present a proteogenomic study of 108 human papilloma virus (HPV)-negative head and neck squamous cell carcinomas (HNSCCs). Proteomic analysis systematically catalogs HNSCC-associated proteins and phosphosites, prioritizes copy number drivers, and
Autor:
Jessica Everett, Xuhong Cao, Jeffrey W. Innis, Rajen Mody, Francis P. Worden, Yi-Mi Wu, David Smith, Javed Siddiqui, Joseph Vijai, Erica Rabban, Moshe Talpaz, Kenneth Offit, Elena M. Stoffel, Daniel F. Hayes, J. Scott Roberts, Ajjai Alva, Chandan Kumar-Sinha, Erin F. Cobain, Robert J. Lonigro, Nithya Ramnath, Marcin Cieślik, Laurence H. Baker, David R. Lucas, Ann F. Schott, Dan R. Robinson, Mark M. Zalupski, Scott A. Tomlins, Victoria M. Raymond, Pankaj Vats, Arul M. Chinnaiyan, Scott M. Schuetze, Lakshmi P. Kunju, Rashmi Chugh
Publikováno v:
Nature
SUMMARY Metastasis is the primary cause of cancer-related deaths. While The Cancer Genome Atlas (TCGA) has sequenced primary tumor types obtained from surgical resections, much less comprehensive molecular analysis is available from clinically acquir