Zobrazeno 11 - 20
of 24
pro vyhledávání: '"Pablo Helguera"'
Autor:
Yuyu Song, Hector Hugo Caicedo, Fiamma Buratti, Emiliano Zamponi, Lisa Jungbauer, Scott T. Brady, Mariano Bisbal, Gabriel Enrique Cataldi, Jiyan Ma, Alfredo Lorenzo, Pablo Helguera, Gerardo Morfini, Gustavo Pigino, Mary Jo LaDu
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188340 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons affected in prion diseases
Autor:
Pablo Helguera, consonni
Como en el mítico cartoon del New Yorker, el artista Pablo Helguera, recupera la técnica de la caricatura para generar un retrato exagerado y a veces distorsionado del mundo del arte. Este libro compila una selección de 187 dibujos, por primera ve
Autor:
Jorge Busciglio, Ryan C. Bohannan, Pablo Helguera, Jean Thomas, Eric Doran, Schriner E. Samuel, Jocelyn Argueta, Zahra Nemati, Pinar Coskun, Douglas C. Wallace, Ira T. Lott
Deficits in mitochondrial function and oxidative stress play pivotal roles in Down syndrome (DS) and Alzheimer's disease (AD) and these alterations in mitochondria occur systemically in both conditions. Objective: We hypothesized that peripheral cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2171022e7666a0906d14bb572d2c6820
https://www.ncbi.nlm.nih.gov/pubmed/27802222
https://www.ncbi.nlm.nih.gov/pubmed/27802222
Publikováno v:
PAJ: A Journal of Performance and Art. 34:169-182
The word “theatre” during the past fifty years has often been used in the art world to denote something detestable, to be avoided at all cost. In the performance art tradition in particular, theatre was condemned because of its base and political
Autor:
José de Olmos, Frank M. LaFerla, Soledad de Olmos, Francisco Solá Vigo, Gabriela Kedikian, Alfredo Cáceres, Matthias Staufenbiel, Alfredo Lorenzo, Pablo Helguera, Lorena Heredia, Jorge Busciglio
Publikováno v:
Journal of Neuroscience. 26:6533-6542
Deposition of fibrillar amyloid beta (fAbeta) plays a critical role in Alzheimer's disease (AD). We have shown recently that fAbeta-induced dystrophy requires the activation of focal adhesion proteins and the formation of aberrant focal adhesion stru
Autor:
Jorge Busciglio, Pablo Helguera, Elizabeth Head, Alejandra Pelsman, Ernst J. Wolvetang, Gustavo Pigino
Publikováno v:
The Journal of Neuroscience. 25:2295-2303
Down's syndrome (DS) is characterized by mental retardation and development of Alzheimer's disease (AD). Oxidative stress and mitochondrial dysfunction are both related to neurodegeneration in DS. Several genes in chromosome 21 have been linked to ne
Autor:
Pablo Helguera
Publikováno v:
Art & the Public Sphere. 4:9-10
Autor:
Pablo Helguera, Jose A. Rodriguez, Michael G. Hanna, Jaqueline Seiglie, Gustavo Helguera, Jorge Busciglio
Publikováno v:
Helguera, P; Seiglie, J; Rodriguez, J; Hanna, M; Helguera, G; & Busciglio, J. (2013). Adaptive Downregulation of Mitochondrial Function in Down Syndrome. CELL METABOLISM, 17(1), 132-140. doi: 10.1016/j.cmet.2012.12.005. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/77m6v7qp
Mitochondrial dysfunction and oxidative stress are common features of Down syndrome (DS). However, the underlying mechanisms are not known. We investigated the relationship between abnormal energy metabolism and oxidative stress with transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8d70af8a1b2926aa7fa819d718aab0
http://www.sciencedirect.com/science/article/pii/S1550413112004962#
http://www.sciencedirect.com/science/article/pii/S1550413112004962#
Publikováno v:
Garcia, O; Torres, M; Helguera, P; Coskun, P; & Busciglio, J. (2010). A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome. PLOS ONE, 5(12). doi: 10.1371/journal.pone.0014200. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7fx008tv
PLoS ONE
Garcia, Octavio; Torres, Maria; Helguera, Pablo; Coskun, Pinar; & Busciglio, Jorge. (2010). A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome. PLoS ONE, 5(12). UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2pw4z82p
PLoS ONE, Vol 5, Iss 12, p e14200 (2010)
PLoS ONE
Garcia, Octavio; Torres, Maria; Helguera, Pablo; Coskun, Pinar; & Busciglio, Jorge. (2010). A Role for Thrombospondin-1 Deficits in Astrocyte-Mediated Spine and Synaptic Pathology in Down's Syndrome. PLoS ONE, 5(12). UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/2pw4z82p
PLoS ONE, Vol 5, Iss 12, p e14200 (2010)
Background Down's syndrome (DS) is the most common genetic cause of mental retardation. Reduced number and aberrant architecture of dendritic spines are common features of DS neuropathology. However, the mechanisms involved in DS spine alterations ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cb4398c2a4f52e121a06e07ad32c479
http://www.escholarship.org/uc/item/7fx008tv
http://www.escholarship.org/uc/item/7fx008tv
Publikováno v:
Journal of Visualized Experiments : JoVE
In this study, we outline a standardized protocol for the successful cryopreservation and thawing of cortical brain tissue blocks to generate highly enriched neuronal cultures. For this protocol the freezing medium used is 10% dimethyl sulfoxide (DMS