Zobrazeno 41 - 50
of 225
pro vyhledávání: '"Oliver M. Sieber"'
Autor:
Oliver M. Sieber, Michael Buchert, Ian Street, Matthias Ernst, Peter Gibbs, Jayesh Desai, Nicholas J. Hawkins, Robyn L. Ward, Cameron J. Nowell, Cary Tsui, Adele Preaudet, Tracy L. Putoczki, Lachlan Whitehead, Shan Li, Robert N. Jorissen, Christopher Love, Michelle Palmieri, Sheng Liu, Bruno Catimel, Ruth N. MacKinnon, Dmitri Mouradov, Marie J. Parsons, Anuratha Sakthianandeswaren
Mouse phenotyping data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f91e86acca7390b39e8e3cbf385540f
https://doi.org/10.1158/2159-8290.22532477
https://doi.org/10.1158/2159-8290.22532477
Autor:
Charles Swanton, Oliver M. Sieber, Zoltan Szallasi, Nicholas J. Hawkins, Robyn L. Ward, Peter Gibbs, Dmitri Mouradov, Tejal Joshi, David Endesfelder, Eva Grönroos, Andrew J. Rowan, Rebecca A. Burrell, Nicholas McGranahan, Sally M. Dewhurst
MOV file 1084K, Cell undergoing a normal mitosis followed by mitosis in the daughter cell (see Supplementary Figure 4 for movie stills)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49aaf8320d97a0c1f603ee4714cf3ba3
https://doi.org/10.1158/2159-8290.22529954
https://doi.org/10.1158/2159-8290.22529954
Autor:
Mauro Delorenzi, Sabine Tejpar, Fred T. Bosman, Arnaud D. Roth, Iris M. Simon, Justin Guinney, Peter Gibbs, Stephen McLaughlin, Ian T. Jones, Peter L. Molloy, Chris Love, Robert N. Jorissen, Oliver M. Sieber, Pratyaksha Wirapati, Edoardo Missiaglia, David Barras
Purpose: Mutation of BRAF at the valine 600 residue occurs in approximately 10% of colorectal cancers, a group with particularly poor prognosis. The response of BRAF mutant colorectal cancer to recent targeted strategies such as anti-BRAF or combinat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::906bd912048bc2f570d04428885aa140
https://doi.org/10.1158/1078-0432.c.6526311.v1
https://doi.org/10.1158/1078-0432.c.6526311.v1
Autor:
Mauro Delorenzi, Sabine Tejpar, Fred T. Bosman, Arnaud D. Roth, Iris M. Simon, Justin Guinney, Peter Gibbs, Stephen McLaughlin, Ian T. Jones, Peter L. Molloy, Chris Love, Robert N. Jorissen, Oliver M. Sieber, Pratyaksha Wirapati, Edoardo Missiaglia, David Barras
Analysis of GO processes enriched in several mTOR signatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae8b97220cf44b9e2096b4b83789806
https://doi.org/10.1158/1078-0432.22466421
https://doi.org/10.1158/1078-0432.22466421
Autor:
Oliver M. Sieber, Peter Gibbs, Robert L. Strausberg, Qi Zhao, Dana Busam, James Moore, Andrew R. Ruszkiewicz, Nicholas J. Hawkins, Robyn L. Ward, Stephen McLaughlin, Ian T. Jones, Barbara A. Leggett, Vicki Whitehall, Peter Molloy, Zheng-Zhou Xu, Jayesh Desai, Jeannie Tie, Cary Tsui, Shan Li, Michael Christie, Anuratha Sakthianandeswaren, Dmitri Mouradov, Lara Lipton, Robert N. Jorissen, Fiona L. Day
PDF file - 716K, Supplementary Table 1. Somatic PIK3CA exon 9 and 20 mutations detected in 1,093 patients with sporadic CRC. Supplementary Table 2. Somatic PTEN exon 3 to 8 mutations detected in 744 patients with sporadic CRC. Supplementary Table 3.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c87c12dc2bda558670f70e40ca25911
https://doi.org/10.1158/1078-0432.22447776.v1
https://doi.org/10.1158/1078-0432.22447776.v1
Autor:
Oliver M. Sieber, David Kerr, Rachel Midgley, Ian P.M. Tomlinson, Enric Domingo, Robert L. Strausberg, Dana Busam, Qi Zhao, Paul McMurrick, Adrian Polglase, Roger Berry, Peter W.G. Carne, Simon Knight, Adrian W. Pick, Peter M. Evans, Valery Usatoff, Benjamin N.J. Thomson, Katharine J. Drummond, Michael Christie, Robert N. Jorissen, Peter Gibbs, Jayesh Desai, Lara Lipton, Jeanne Tie
Purpose: Oncogene mutations contribute to colorectal cancer development. We searched for differences in oncogene mutation profiles between colorectal cancer metastases from different sites and evaluated these as markers for site of relapse.Experiment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9118783b7f4d2aee21297d4a85d69a97
https://doi.org/10.1158/1078-0432.c.6520413.v1
https://doi.org/10.1158/1078-0432.c.6520413.v1
Autor:
Mauro Delorenzi, Sabine Tejpar, Fred T. Bosman, Arnaud D. Roth, Iris M. Simon, Justin Guinney, Peter Gibbs, Stephen McLaughlin, Ian T. Jones, Peter L. Molloy, Chris Love, Robert N. Jorissen, Oliver M. Sieber, Pratyaksha Wirapati, Edoardo Missiaglia, David Barras
Figure S1. Principal component analysis and hierarchical clustering of the 218 BRAF mutant patient cohort;Figure S2: Gene-wise and patient-wise biclustering heatmap of the 218 BRAF mutant patient cohort and comparison of BRAF mutant subtypes obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef2340ef1af66e9d9ae38cc413682c5
https://doi.org/10.1158/1078-0432.22466433.v1
https://doi.org/10.1158/1078-0432.22466433.v1
Autor:
Oliver M. Sieber, David Kerr, Rachel Midgley, Ian P.M. Tomlinson, Enric Domingo, Robert L. Strausberg, Dana Busam, Qi Zhao, Paul McMurrick, Adrian Polglase, Roger Berry, Peter W.G. Carne, Simon Knight, Adrian W. Pick, Peter M. Evans, Valery Usatoff, Benjamin N.J. Thomson, Katharine J. Drummond, Michael Christie, Robert N. Jorissen, Peter Gibbs, Jayesh Desai, Lara Lipton, Jeanne Tie
Supplementary Tables S1-S4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4726b73d659946e0105b66a11a7b47
https://doi.org/10.1158/1078-0432.22445193
https://doi.org/10.1158/1078-0432.22445193
Autor:
Oliver M. Sieber, Claus Lindbjerg Andersen, Torben F. Ørntoft, Mogens Kruhøffer, Lauri A. Aaltonen, Hein W. Verspaget, Ian P.M. Tomlinson, Philip East, Timothy J. Yeatman, Ian T. Jones, Jayesh Desai, Matthew Chapman, Peter Gibbs, Lara Lipton, Robert N. Jorissen
Supplementary Data from DNA Copy-Number Alterations Underlie Gene Expression Differences between Microsatellite Stable and Unstable Colorectal Cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e994fe1e44acdc18653c6dc1679597
https://doi.org/10.1158/1078-0432.22439283
https://doi.org/10.1158/1078-0432.22439283
Autor:
Oliver M. Sieber, Timothy J. Yeatman, Steven Eschrich, Vidya P. Kamath, Mike Gruidl, Claus Lindbjerg Andersen, Torben F. Ørntoft, Mogens Kruhøffer, Diego Arango, Lauri A. Aaltonen, David Kerr, Jayesh Desai, Lara Lipton, Saurabh Prakash, Michael Christie, Peter Gibbs, Robert N. Jorissen
Purpose: Colorectal cancer prognosis is currently predicted from pathologic staging, providing limited discrimination for Dukes stage B and C disease. Additional markers for outcome are required to help guide therapy selection for individual patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22d51c7854ce3346cccf75880f9ff35e
https://doi.org/10.1158/1078-0432.c.6517435.v1
https://doi.org/10.1158/1078-0432.c.6517435.v1