Zobrazeno 101 - 110
of 251
pro vyhledávání: '"Norio Asou"'
Publikováno v:
Haematologica. 94:433-435
A JAK2 -V617F mutation was found in 3 of 45 (6.7%) patients with t(8;21) acute myeloid leukemia (AML), whereas only one of 137 (0.7%) patients with de novo AML other than t(8;21) had the same mutation ( p =0.047). We examined the clinical significanc
Autor:
Yasuhiro Yamada, Eisaku Iwanaga, Norio Asou, Hiroaki Mitsuya, Tomoko Nanri, Kentaro Horikawa, Satomi Fujie
Publikováno v:
International Journal of Hematology. 89:139-141
The echinocandins provide an attractive new option for prophylactic and empirical treatment of invasive fungal infections in patients with neutropenia after intensive cytotoxic chemotherapy or hematopoietic stem cell transplantation. We present two p
Autor:
Ikuo Murohashi, Norio Asou, Kunitake Hirashima, Satoru Yoshida, Itsuro Jinnai, Akira Matsuda, S Kusumoto, Fumiharu Yagasaki, Masami Bessho, Yasuko Yokoyama, Hirofumi Kobayashi, Kazuma Ohyashiki, Hiroshi Terasaki
Publikováno v:
Genes, Chromosomes and Cancer. 26:192-202
We identified a novel human long fatty acyl CoA synthetase 2 gene, ACS2, as a new ETV6 fusion partner gene in a recurrent t(5;12)(q31;p13) translocation in a patient with refractory anemia with excess blasts (RAEB) with basophilia, a patient with acu
Autor:
Essam Abdalla, Katsuya Shigesada, Yoshiaki Ito, Koyu Hoshino, Kiyoshi Takatsuki, Tomohiko Kanno, Motomi Osato, Norio Asou, Hitoshi Suzushima, Toshiya Okubo, Hiroshi Yamasaki
Publikováno v:
Blood. 93:1817-1824
The AML1 gene encoding the DNA-binding -subunit in the Runt domain family of heterodimeric transcription factors has been noted for its frequent involvement in chromosomal translocations associated with leukemia. Using reverse transcriptase-polyme
Autor:
Tomoki Naoe, Yasuyuki Nakano, Norio Asou, Hitoshi Kiyoi, Hidehiko Saito, Ryuzo Ohno, Shuichi Miyawaki
Publikováno v:
British Journal of Haematology. 104:659-664
Relapse is a major cause of treatment failure in acute myeloid leukaemia (AML), and is usually accompanied by resistance to chemotherapy. To study whether relapse is accompanied by genetic alterations, we compared N-ras, p53 and FLT3 gene mutations i
Autor:
Kisato Nosaka, Kiyoharu Ito, Norio Asou, Yasuhiro Yamada, Fumio Kawano, Yutaka Sasaki, Yuko Watanabe, Michihiro Hidaka, Hiroaki Mitsuya, Kentaro Horikawa
Publikováno v:
Leukemia Research. 32:1944-1946
Autor:
Tomoki Naoe, Syuichi Miyawaki, Yasusada Miura, Ryuzo Ohno, Kunitake Hirashima, Hideaki Mizoguchi, Kensuke Naito, Toshihiko Kobayashi, Yasuo Morishima, Kazuo Tsubaki, Ohshima T, Mitsuhiro Omine, Mitsune Tanimoto, Masao Tomonaga, Isao Takahashi, Shigeki Ohtake, Hiroo Dohy, Kazunori Ohnishi, Atsushi Kuramoto, Nanao Kamada, Norio Asou, A. Sakuma, K. Onozawa
Publikováno v:
Leukemia Research. 22:779-786
To evaluate the long-term effectiveness of interferon- α (IFN- α ) therapy in patients with chronic myelogenous leukemia (CML) in chronic phase, we examined the updated outcomes of 159 patients who had been enrolled between 1988 and 1991 into a ran
Autor:
Yoshiharu Izuno, Hiroshi Ueno, Hiroaki Mitsuya, Kazuhiko Ide, Norio Asou, Toshiya Okubo, Makoto Kawakita, Hiroyuki Hata
Publikováno v:
International Journal of Hematology. 86:69-71
We present a patient with refractory multiple myeloma who showed a good response to a combination therapy with oral melphalan, dexamethasone, and thalidomide (MDT). A 48-year-old woman with myeloma refractory to thalidomide, dexamethasone, and clarit
Autor:
Hiroshi Yamasaki, Koyu Hoshino, Norio Asou, Toshiya Okubo, Kiyoshi Takatsuki, Shintaro Nishimura, Motomi Osato, Takumi Era, Hitoshi Suzushima
Publikováno v:
Leukemia & Lymphoma. 31:81-91
As recurrent chromosome abnormalities in leukemia are highly associated with particular subtypes, the genetic events of specific chromosome alteration must be associated with leukemogenesis and characteristics of the disease. The chromosomal breakpoi
Autor:
Hiroko Shiozaki, Hideo Takeyama, Akihisa Kanamaru, Tohru Kobayashi, Ryuzo Ohno, Fumimaro Takaku, Kiyoshi Nishikawa, Yasusada Miura, Osamu Yamada, Koji Tsukuda, Kiyohiko Hatake, Norio Asou, Tohru Masaoka, Yoshihisa Kodera, Kazuo Motoyoshi, Kazutaka Kuriyama, Kenji Saito, Masao Tomonaga, Mitsune Tanimoto, Shuichi Miyawaki, Eijiro Omoto, Yasuo Ohashi, Shin Matsuda
Publikováno v:
Journal of Clinical Oncology. 15:2954-2965
PURPOSE To determine whether macrophage colony-stimulating factor (M-CSF) reduces the incidence and duration of febrile neutropenia during three courses of intensive consolidation therapy and whether it shortens time to complete consolidation therapy