Zobrazeno 31 - 40
of 336
pro vyhledávání: '"Nir Friedman"'
Publikováno v:
PLoS Computational Biology, Vol 4, Iss 2, p e1000010 (2008)
Characterizing the DNA-binding specificities of transcription factors is a key problem in computational biology that has been addressed by multiple algorithms. These usually take as input sequences that are putatively bound by the same factor and out
Externí odkaz:
https://doaj.org/article/35c8dc07046d4c68a61496e18f5af900
Autor:
Chih Long Liu, Tommy Kaplan, Minkyu Kim, Stephen Buratowski, Stuart L Schreiber, Nir Friedman, Oliver J Rando
Publikováno v:
PLoS Biology, Vol 3, Iss 10, p e328 (2005)
Covalent modification of histone proteins plays a role in virtually every process on eukaryotic DNA, from transcription to DNA repair. Many different residues can be covalently modified, and it has been suggested that these modifications occur in a g
Externí odkaz:
https://doaj.org/article/283bec7b49e34ba0be6bee413818ec07
Publikováno v:
PLoS Biology, Vol 3, Iss 7, p e238 (2005)
The SOS genetic network is responsible for the repair/bypass of DNA damage in bacterial cells. While the initial stages of the response have been well characterized, less is known about the dynamics of the response after induction and its shutoff. To
Externí odkaz:
https://doaj.org/article/ad1734b9976246eda7b11d29ebc09d59
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 1, p e1 (2005)
Current approaches for identification and detection of transcription factor binding sites rely on an extensive set of known target genes. Here we describe a novel structure-based approach applicable to transcription factors with no prior binding data
Externí odkaz:
https://doaj.org/article/c6fee00d683b49d28cc855c09376b7f2
Autor:
Aaron Javitt, Merav D. Shmueli, Matthias P. Kramer, Aleksandra A. Kolodziejczyk, Ivan J. Cohen, Lihi Radomir, Daoud Sheban, Iris Kamer, Kevin Litchfield, Elizabeta Bab-Dinitz, Oranit Zadok, Vanessa Neiens, Adi Ulman, Hila Wolf-Levy, Avital Eisenberg-Lerner, Assaf Kacen, Michal Alon, Ana Toste Rêgo, Elvira Stacher-Priehse, Michael Lindner, Ina Koch, Jair Bar, Charles Swanton, Yardena Samuels, Yishai Levin, Paula C. A. da Fonseca, Eran Elinav, Nir Friedman, Silke Meiners, Yifat Merbl
Publikováno v:
Nature Cancer. 4:629-647
Autor:
Rakefet Sidlik Muskatel, Bar Nathansohn-Levi, Shlomit Reich-Zeliger, Michal Mark, Liat Stoler-Barak, Chava Rosen, Irit Milman-Krentsis, Esther Bachar Lustig, Robert Pete Gale, Nir Friedman, Yair Reisner
Publikováno v:
Stem Cells Translational Medicine. 12:281-292
The induction of partial tolerance toward pancreatic autoantigens in the treatment of type 1 diabetes mellitus (T1DM) can be attained by autologous hematopoietic stem cell transplantation (HSCT). However, most patients treated by autologous HSCT even
Autor:
Lőrinc Sándor Pongor, Christopher W. Schultz, Lorenzo Rinaldi, Darawalee Wangsa, Christophe E. Redon, Nobuyuki Takahashi, Gavriel Fialkoff, Parth Desai, Yang Zhang, Sandra Burkett, Nadav Hermoni, Noa Vilk, Jenia Gutin, Rona Gergely, Yongmei Zhao, Samantha Nichols, Rasa Vilimas, Linda Sciuto, Chante Graham, Juan Manuel Caravaca, Sevilay Turan, Shen Tsai-wei, Vinodh N. Rajapakse, Rajesh Kumar, Deep Upadhyay, Suresh Kumar, Yoo Sun Kim, Nitin Roper, Bao Tran, Stephen M. Hewitt, David E. Kleiner, Mirit I. Aladjem, Nir Friedman, Gordon L. Hager, Yves Pommier, Thomas Ried, Anish Thomas
Publikováno v:
Cancer Discovery. 13:928-949
Small-cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. Oncogenic MYC amplifications drive SCLC heterogeneity, but the genetic mechanisms of MYC amplification and phenotypic plasticity, characterized by neuroendocrine and nonneuroe
Autor:
Anish Thomas, Thomas Ried, Yves Pommier, Gordon L. Hager, Nir Friedman, Mirit I. Aladjem, David E. Kleiner, Stephen M. Hewitt, Bao Tran, Nitin Roper, Yoo Sun Kim, Suresh Kumar, Deep Upadhyay, Rajesh Kumar, Vinodh N. Rajapakse, Shen Tsai-wei, Sevilay Turan, Juan Manuel Caravaca, Chante Graham, Linda Sciuto, Rasa Vilimas, Samantha Nichols, Yongmei Zhao, Rona Gergely, Jenia Gutin, Noa Vilk, Nadav Hermoni, Sandra Burkett, Yang Zhang, Parth Desai, Gavriel Fialkoff, Nobuyuki Takahashi, Christophe E. Redon, Darawalee Wangsa, Lorenzo Rinaldi, Christopher W. Schultz, Lőrinc Sándor Pongor
ecDNA in SCLC, related to Figure 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc364e23dd8ec76bf9c7c808ebeba99
https://doi.org/10.1158/2159-8290.22553442
https://doi.org/10.1158/2159-8290.22553442
Autor:
Anish Thomas, Thomas Ried, Yves Pommier, Gordon L. Hager, Nir Friedman, Mirit I. Aladjem, David E. Kleiner, Stephen M. Hewitt, Bao Tran, Nitin Roper, Yoo Sun Kim, Suresh Kumar, Deep Upadhyay, Rajesh Kumar, Vinodh N. Rajapakse, Shen Tsai-wei, Sevilay Turan, Juan Manuel Caravaca, Chante Graham, Linda Sciuto, Rasa Vilimas, Samantha Nichols, Yongmei Zhao, Rona Gergely, Jenia Gutin, Noa Vilk, Nadav Hermoni, Sandra Burkett, Yang Zhang, Parth Desai, Gavriel Fialkoff, Nobuyuki Takahashi, Christophe E. Redon, Darawalee Wangsa, Lorenzo Rinaldi, Christopher W. Schultz, Lőrinc Sándor Pongor
Enhancer-enhancer interaction results of MYC and MYCL ecDNAs in the DMS-273 cell line.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ade2d2222ae80c0ff9384da09bf24578
https://doi.org/10.1158/2159-8290.22553409.v1
https://doi.org/10.1158/2159-8290.22553409.v1
Autor:
Anish Thomas, Thomas Ried, Yves Pommier, Gordon L. Hager, Nir Friedman, Mirit I. Aladjem, David E. Kleiner, Stephen M. Hewitt, Bao Tran, Nitin Roper, Yoo Sun Kim, Suresh Kumar, Deep Upadhyay, Rajesh Kumar, Vinodh N. Rajapakse, Shen Tsai-wei, Sevilay Turan, Juan Manuel Caravaca, Chante Graham, Linda Sciuto, Rasa Vilimas, Samantha Nichols, Yongmei Zhao, Rona Gergely, Jenia Gutin, Noa Vilk, Nadav Hermoni, Sandra Burkett, Yang Zhang, Parth Desai, Gavriel Fialkoff, Nobuyuki Takahashi, Christophe E. Redon, Darawalee Wangsa, Lorenzo Rinaldi, Christopher W. Schultz, Lőrinc Sándor Pongor
Small-cell lung cancer (SCLC) is an aggressive neuroendocrine lung cancer. Oncogenic MYC amplifications drive SCLC heterogeneity, but the genetic mechanisms of MYC amplification and phenotypic plasticity, characterized by neuroendocrine and nonneuroe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de78f78b54345017eb684fdc765dadc
https://doi.org/10.1158/2159-8290.c.6534631.v2
https://doi.org/10.1158/2159-8290.c.6534631.v2