Zobrazeno 11 - 20
of 45
pro vyhledávání: '"Nils Rudqvist"'
Autor:
Daniel K. Wells, Erik Wennerberg, Benjamin G. Vincent, Christine N. Spencer, Heather M. McGee, Yana G. Najjar, Nils Rudqvist, Randy F. Sweis, Anne Monette, Houssein Abdul Sater, Uqba Khan, Maria Libera Ascierto, Cara Haymaker, Nicholas Tschernia, Praveen K. Bommareddy, Roberta Zappasodi, Vinita Popat, Sara Valpione, Alexandria P. Cogdill, Valentin Barsan, Vesteinn Thorsson, Wungki Park
Publikováno v:
Poster Presentations.
Background Immune checkpoint blockade (ICB) has revolutionized cancer treatment. However, long-term benefits are only achieved in a small fraction of patients. Understanding the mechanisms underlying ICB activity is key to improving the efficacy of i
Autor:
Chao Sima, Dunstana R. Melo, Sally A. Amundson, Shad R. Morton, Nils Rudqvist, Waylon Weber, Helen Turner, Shanaz A. Ghandhi
Publikováno v:
Radiat Res
Internal contamination by radionuclides may constitute a major source of exposure and biological damage after radiation accidents and potentially in a dirty bomb or improvised nuclear device scenario. We injected male C57BL/6 mice with radiolabeled c
Tumor infiltration of conventional dendritic cells has been shown to be essential for triggering efficient antitumor immune responses. These findings have generated an increasing demand for reliable methods to accurately identify and quantify specifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e229e016f92b96077e93ec470975597
https://doi.org/10.1016/bs.mie.2020.01.011
https://doi.org/10.1016/bs.mie.2020.01.011
Exosomes are small extracellular vesicles released by prokaryotic and eukaryotic cells with a crucial role in cell-to-cell communication in both physiological and pathological conditions. Exosomes contain and transfer active biomolecules, including n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a2a7da0f81554157dc89532cddc4185
https://doi.org/10.1016/bs.mie.2020.01.012
https://doi.org/10.1016/bs.mie.2020.01.012
Autor:
Karsten A. Pilones, Jonathan P. Schneck, John-William Sidhom, Harlan Robins, Silvia C. Formenti, Erik Wennerberg, Claire Lhuillier, Sandra Demaria, Ryan O. Emerson, Nils Rudqvist
Publikováno v:
Cancer Immunology Research. 6:139-150
Immune checkpoint inhibitors activate T cells to reject tumors. Unique tumor mutations are key T-cell targets, but a comprehensive understanding of the nature of a successful antitumor T-cell response is lacking. To investigate the T-cell receptor (T
Autor:
Eva Forssell-Aronsson, Khalil Helou, Britta Langen, Nils Rudqvist, Johan Spetz, Ola Nilsson, Toshima Z. Parris
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-11 (2017)
Background 177Lu-octreotate can be used to treat somatostatin receptor expressing neuroendocrine tumors. It is highly effective in animal models, but clinical studies have so far only demonstrated low cure rates. Hedgehog inhibitors have shown therap
Publikováno v:
Journal of Nuclear Medicine. 58:346-353
Targeted a-therapy is a promising treatment option for various types of malignant tumors. Radiolabeled cancer-seeking agents, however, undergo degradation, resulting in a certain percentage of free radionuclide in the body. The radiohalogen 211At acc
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-10 (2019)
Genome Medicine
Genome Medicine
The expression of antigens that are recognized by self-reactive T cells is essential for immune-mediated tumor rejection by immune checkpoint blockade (ICB) therapy. Growing evidence suggests that mutation-associated neoantigens drive ICB responses i
Autor:
Abraham Chachoua, Adriana Heguy, Silvia C. Formenti, Erik Wennerberg, Kai W. Wucherpfennig, Tuo Zhang, Naoko Imai, Sacha Gnjatic, Encouse B. Golden, Xi Kathy Zhou, Kent Friedman, Benjamin T. Cooper, Sandra Demaria, Ryan O. Emerson, Nils Rudqvist, Claire Lhuillier, Lucas Ferrari de Andrade, Claire Vanpouille-Box
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-3 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-3 (2019)
Focal radiation therapy enhances systemic responses to anti-CTLA-4 antibodies in preclinical studies and in some patients with melanoma1-3, but its efficacy in inducing systemic responses (abscopal responses) against tumors unresponsive to CTLA-4 blo