Zobrazeno 51 - 60
of 93
pro vyhledávání: '"Nathan Standifer"'
Autor:
Crystal S. Denlinger, S. Krishnan, Michael S. Gordon, Naiyer A. Rizvi, Nathan Standifer, J. Cann, Ani Sarkis Balmanoukian, A. Perera, Ashish V. Chintakuntlawar, Raid Aljumaily, Paolo Vicini, J. R. Infante, N. Durham, M. Ma, L. Yan, Aung Naing, Helen J. Ross, Ritesh Kumar
Publikováno v:
Annals of Oncology. 29:viii411
Autor:
Sophie Postel-Vinay, Christine Stephens, Juanita Lopez, Emma Dean, Amy Cheung, Paul Frewer, Andrew J. Pierce, Nathan Standifer, Simon J. Hollingsworth, S.-A. Im, Gemma N Jones, Y.-J. Bang, Leila Khoja, Alienor Berges, Brunella Felicetti, Anthony B. El-Khoueiry, Paola Marco-Casanova, W. Abidah, Matthew G Krebs
Publikováno v:
Annals of Oncology. 29:viii135
Autor:
T. Alonso Gordoa, Xia Li, Ding Wang, Chris Morehouse, Hormas Ghadially, M. Jure-Kunkel, Sandip Pravin Patel, J. Rodriguez Canales, M.J. Flor Oncala, Nathan Standifer, Jennifer R. Diamond, Marlon Rebelatto, D.C. Jones, Maria Libera Ascierto, Shaad Essa Abdullah, Jarushka Naidoo, Matthew D. Hellmann, L. Mazzarella, Xuyang Song, Simon J. Marshall
Publikováno v:
Annals of Oncology. 29:viii425
Autor:
S. Alice Long, Paul L. Bollyky, Gregory E. Holt, Anton Preisinger, Ben A. Falk, Brandon Teng, Nathan Standifer, Cindy Fang Xie, Gerald T. Nepom, John A. Gebe, Kathleen R. Braun, Robert B. Vernon, Peter L. Samuels, Rebecca P. Wu, James D. Lord, Thomas N. Wight
Publikováno v:
Proceedings of the National Academy of Sciences. 108:7938-7943
We describe a role for ECM as a biosensor for inflammatory microenvironments that plays a critical role in peripheral immune tolerance. We show that hyaluronan (HA) promotes induction of Foxp3- IL-10–producing regulatory T cells (TR1) from conventi
Autor:
Nathan Standifer, Carla J. Greenbaum, Gerald T. Nepom, Jenna Bollyky, Srinath Sanda, Jessica A. Hamerman
Publikováno v:
Clinical Immunology. 136:170-173
Objective Interleukin 1-beta (IL-1β) is a major inflammatory cytokine. Blockade of the IL-1β pathway is therapeutically efficacious in type 2 diabetes, but the mechanistic effects on the immune system are incompletely understood. Research design We
Autor:
Matthew G Krebs, Kevin J. Harrington, S.Y. Amy Cheung, Alienor Berges, Simon Smith, Alan Lau, Brunella Felicetti, Andrew J. Pierce, James W.T. Yates, Emma Dean, Simon J. Hollingsworth, Christine Stephens, Nathan Standifer
Publikováno v:
Cancer Research. 78:CT118-CT118
Introduction: AZD6738 is a potent inhibitor of the ATR protein kinase that is being tested in patients with solid malignancies. In Phase I dose escalation studies, AZD6738 was dosed as monotherapy (continuous schedule from 40 - 480 mg per day), or in
Autor:
Robert J. Kreitman, Nathan Standifer, G. Saglio, Bjørn Tore Gjertsen, Pier Luigi Zinzani, Phillipp D. Le Coutre, Xavier Troussard, Gail J. Roboz, Claire Dearden, Wyndham H. Wilson, Francis J. Giles, Kemal Balic, Douglas E. Gladstone, Lionel Karlin, Peng He, Shannon Marshall, Nai-Shun Yao, Julio Delgado, Tadeusz Robak, Ira Pastan
Publikováno v:
Journal of Clinical Oncology. 36:7004-7004
7004Background: A pivotal multicenter, single-arm study evaluated moxetumomab pasudotox, a first-in-class recombinant immunotoxin, in patients (pts) with relapsed/refractory hairy cell leukemia (HC...
Autor:
Robert J. Kreitman, Chih-Ming Tseng, Kemal Balic, Meina Liang, Linda Santiago, Nathan Standifer, Denison Kuruvilla, Nai-Shun Yao, Ira Pastan, Xia Li, Raffaella Faggioni, Lorin Roskos, Inna Vainshtein
Publikováno v:
Journal of Clinical Oncology. 36:7061-7061
7061Background: Moxe is a recombinant immunotoxin that specifically binds to CD22 on the B cell surface and internalizes leading to cell death. The PK, PD, and immunogenicity of moxe were evaluated...
Autor:
Martin, Schwickart, Carlos, Chavez, Simon, Henderson, Inna, Vainshtein, Nathan, Standifer, Christopher, DelNagro, Freshta, Mehrzai, Amy, Schneider, Lorin, Roskos, Meina, Liang
Publikováno v:
Cytometry. Part B, Clinical Cytometry
Background Receptor occupancy (RO) assays provide a means to measure the direct interaction of therapeutics with their cell surface targets. Free receptor assays quantify cell‐surface receptors not bound by a therapeutic while total receptor assays
Autor:
Heike Wulff, Christine Beeton, Jamshid Tehranzadeh, Nathan Standifer, Stephen M Griffey, Werner W. Roeck, Christine J. LeeHealey, Philippe Azam, Brian S. Andrews, Alexandra Grino, Debra Counts, K. George Chandy, George A. Gutman, Kimber L. Stanhope, Ananthakrishnan Sankaranarayanan, Ping H. Wang, Katherine M. Mullen, Daniel Homerick, Pavel I. Zimin, Peter J. Havel, Michael W. Pennington, Aaron Kolski-Andreaco, Eric Wei, Peter A. Calabresi, Gerald T. Nepom, Hans Guenther Knaus
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, vol 103, iss 46
Beeton, Christine; Wulff, Heike; Standifer, Nathan E; Azam, Philippe; Mullen, Katherine M; Pennington, Michael W; et al.(2006). Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.. Proceedings of the National Academy of Sciences of the United States of America, 103(46), 17414-17419. doi: 10.1073/pnas.0605136103. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2647b9c5
Beeton, Christine; Wulff, Heike; Standifer, Nathan E; Azam, Philippe; Mullen, Katherine M; Pennington, Michael W; et al.(2006). Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.. Proceedings of the National Academy of Sciences of the United States of America, 103(46), 17414-17419. doi: 10.1073/pnas.0605136103. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/2647b9c5
Autoreactive memory T lymphocytes are implicated in the pathogenesis of autoimmune diseases. Here we demonstrate that disease-associated autoreactive T cells from patients with type-1 diabetes mellitus or rheumatoid arthritis (RA) are mainly CD4+CCR7