Zobrazeno 31 - 40
of 64
pro vyhledávání: '"Natalia Kurepina"'
Publikováno v:
Seminars in Respiratory and Critical Care Medicine. 29:467-480
Molecular biology has revolutionized the field of tuberculosis (TB) research. Comparative genomics and molecular epidemiology are providing revelations about the evolutionary origins of MYCOBACTERIUM TUBERCULOSIS and phylogenetic relationships betwee
Autor:
Andrea L. Gibson, Barry N. Kreiswirth, Philip Noel Suffys, Neio Boechat, Milena J. Virginio, Natalia Kurepina, John L. Ho, José Roberto Lapa e Silva, Richard C. Huard, Harrison Magdinier Gomes, Luiz Claudio Oliveira Lazzarini, Elena Shashkina, W. Ray Butler, Fernanda Carvalho de Queiroz Mello, Ana Grazia Marsico, Maranibia Aparecida Cardoso Oelemann
Publikováno v:
Journal of Clinical Microbiology. 45:3891-3902
The current study evaluated Mycobacterium tuberculosis isolates from Rio de Janeiro, Brazil, for genomic deletions. One locus in our panel of PCR targets failed to amplify in ∼30% of strains. A single novel long sequence polymorphism (>26.3 kb) was
Autor:
Barry N. Kreiswirth, Gennaro De Libero, Amit Singhal, Yee Tang Wang, Melvin Khee-Shing Leow, Bhairav Paleja, Liu Jie, Francesca Zolezzi, Pavanish Kumar, Jinmiao Chen, Gilla Kaplan, Liana Tsenova, Gan Suay Hong, Michael Poidinger, Natalia Kurepina, Cynthia B.E. Chee
Publikováno v:
Science translational medicine. 6(263)
The global burden of tuberculosis (TB) morbidity and mortality remains immense. A potential new approach to TB therapy is to augment protective host immune responses. We report that the antidiabetic drug metformin (MET) reduces the intracellular grow
Autor:
Pablo Bifani, Judith R. Glynn, Kristin Kremer, Barry N. Kreiswirth, Dick van Soolingen, Stefan Niemann, Troels Lillebaek, Natalia Kurepina
Publikováno v:
Journal of Clinical Microbiology. 42:4040-4049
Mycobacterium tuberculosis Beijing genotype strains are highly prevalent in Asian countries and in the territory of the former Soviet Union. They are increasingly reported in other areas of the world and are frequently associated with tuberculosis ou
Autor:
S. Joy Milan, Peter D. McElroy, Natalia Kurepina, Barry N. Kreiswirth, Kirsten A. Hauge, Stefan V. Goldberg, Masahiro Narita, Kathryn H. Lofy, Charles M. Nolan, Gerard A. Cangelosi
Publikováno v:
Journal of Clinical Microbiology. 42:1064-1068
The N and W-Beijing families of Mycobacterium tuberculosis are phylogenetically closely related. The ability of the W-Beijing family to rapidly cause widespread disease is well described; however, few outbreaks involving the N family have been report
Autor:
Elena Shashkina, Kenneth L. Shilkret, Barun Mathema, Bonita T. Mangura, Soraya L. Moghazeh, Jack T. Crawford, Jeffrey Driscoll, Pablo Bifani, Barry N. Kreiswirth, Richard Frothingham, Lauren M. Steinlein, Natalia Kurepina, Shannon Campbell, Salvatore A. E. Marras
Publikováno v:
The Journal of Infectious Diseases. 185:641-649
A cohort of 56 patients infected with related strains of Mycobacterium tuberculosis, the S75 group, was identified in a New Jersey population-based study of all isolates with a low number of copies of the insertion element IS6110. Genotyping was comb
Factors affecting tuberculosis strain success over 10 years in a high TB- and HIV-burdened community
Autor:
Elena Shashkina, Barun Mathema, Landon Myer, Andrew Whitelaw, Barry N. Kreiswirth, Linda-Gail Bekker, Keren Middelkoop, Gilla Kaplan, Robin Wood, Natalia Kurepina
Background: Factors associated with Mycobacterium tuberculosis (Mtb) strain success over time in high burdened communities are unknown. Methods: Mtb isolates collected over 10 years from sputum-positive tuberculosis (TB) patients resident in the stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d6acc33d6b72226766d2fa78f22b59
https://europepmc.org/articles/PMC4121554/
https://europepmc.org/articles/PMC4121554/
Autor:
Bonnie B. Plikaytis, Barry N. Kreiswirth, Charles L. Woodley, R. Fleischmann, Natalia Kurepina, Thomas M. Shinnick
Publikováno v:
Tubercle and Lung Disease. 79:273-278
Setting: Mycobacterium tuberculosis strain CDC1551 outbreak area in Tennessee and Kentucky and selected locations in the USA. Objective: Develop a PCR assay to distinguish the highly transmissible CDC1551 from strains which have similar 4-band IS6110
Autor:
D. van Sooligen, Bonnie B. Plikaytis, Natalia Kurepina, Srinand Sreevatsan, Pablo Bifani, James M. Musser, Nancy D. Connell, Robert J. Donnelly, Barry N. Kreiswirth
Publikováno v:
Tubercle and Lung Disease. 79:31-42
Setting: Five IS6110chromosomal insertion sites were characterized in the multidrug resistantMycobacterium tuberculosis‘W’ strain. Objective: To use insertion site probes to study the phylogenetic distribution of IS610in theM. tuberculosisgenome.
Publikováno v:
Journal of applied microbiology. 115(4)
Aims The aim of this study was to test the growth inhibition activity of isothiocyanates (ITCs), defence compounds of plants, against common human microbial pathogens. Methods and Results In this study, we have tested the growth-inhibitory activity o