Zobrazeno 51 - 60
of 166
pro vyhledávání: '"Nan-Ping Weng"'
Autor:
Alvin Shi, Nai-Lin Cheng, Xiaochun Chen, Robert P. Wersto, Cuong Q. Nguyen, Nan-ping Weng, Jiewan Kim
Publikováno v:
Aging Cell
Chemokines play a pivotal role in regulating the immune response through a tightly controlled expression. Elevated levels of inflammatory chemokines commonly occur with aging but the mechanism underlying this age-associated change is not fully unders
Autor:
Palchamy Elango, Hans B. Liu, Luigi Ferrucci, Ana Lustig, Melissa A. Swaby, Richard J. Hodes, E. Jeffrey Metter, Nan-ping Weng, Yang An
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Frontiers in Immunology
Frontiers in Immunology
A number of biological parameters have been cited as hallmarks of immune aging. However, it is not clear whether these multiple biological changes are the result of common underlying aging processes and follow correlated trajectories, or whether the
Publikováno v:
The Journal of biological chemistry. 292(45)
Influenza A virus (IAV) causes an acute infection in humans that is normally eliminated by CD8+ cytotoxic T lymphocytes. Individuals expressing the MHC class I molecule HLA-A2 produce cytotoxic T lymphocytes bearing T-cell receptors (TCRs) that recog
Autor:
achouak achour, Guobing Chen, Alexei Sharov, Thomas Nguyen, Xiang Li, Michael Patrick, William Wood, Supriyo De, Kevin Becker, Weiqun Peng, Nan-Ping Weng
Publikováno v:
The Journal of Immunology. 202:65.14-65.14
Aging of immune system is characterized by progressive decline of physiological and cellular function of T cells, leading to a reduced immune function in the old. Recent studies of naïve T cells from young and old mice have identified age-related al
Autor:
Mark H. O'Hara, Cécile Alanio, Josephine R. Gies, Joseph J Melenhorst, Simon F. Lacey, Nan Ping Weng, Bertram Bengsch, Sarah E. Henrickson, Regina M. Young, Carl H. June, E. John Wherry, Janáe A Ritz-Romeo
Publikováno v:
Cancer Immunology Research. 7:A123-A123
To understand potential immune system alterations in newly diagnosed, untreated, pancreatic cancer patients and provide a foundation for immunotherapy, we profiled PBMC from pancreatic ductal adenocarcinoma (PDA) patients and age-matched healthy cont
Autor:
Qin Yao, Doyle, Máire E., Qing-Rong Liu, Appleton, Ashley, O'Connell, Jennifer F., Nan-ping Weng, Egan, Josephine M.
Publikováno v:
NEJM Evidence; Sep2023, Vol. 2 Issue 9, p8-8, 1p
Autor:
Nan-ping Weng, Elizabeth Garabedian, Irini Sereti, Evert van Dijk, Lauren K. Yokomizo, Fabio Candotti, Virginia Sheikh, John S. Barber, Robert A. Sokolic, Joshua D. Milner, Alexandra F. Freeman
Publikováno v:
Proceedings of the National Academy of Sciences. 110:8164-8169
The ability of T-cells to respond to foreign antigens and to appropriately regulate this response is crucial for maintaining immune homeostasis. Using combinatorial peptide libraries, we functionally measured broad T-cell reactivity and observed impa
Autor:
Guobing, Chen, Xinbo, Yang, Annette, Ko, Xiaoping, Sun, Mingming, Gao, Yongqing, Zhang, Alvin, Shi, Roy A, Mariuzza, Nan-Ping, Weng
Publikováno v:
Cell reports. 19(3)
A diverse T cell receptor (TCR) repertoire is essential for controlling viral infections. However, information about TCR repertoires to defined viral antigens is limited. We performed a comprehensive analysis of CD8+ TCR repertoires for two dominant
Autor:
Marcel R.M. van den Brink, Yoshiko Kubo, Kei Nakachi, Waka Ohishi, Yoichiro Kusunoki, Jae-Hung Shieh, Malcolm A.S. Moore, Munechika Misumi, Kengo Yoshida, Seishi Kyoizumi, Tomonori Hayashi, Lauren F. Young, Junko Kajimura, Kazue Imai, Nan-ping Weng
Accumulated DNA damage in hematopoietic stem cells is a primary mechanism of aging-associated dysfunction in human hematopoiesis. About 70 years ago, atomic-bomb (A-bomb) radiation induced DNA damage and functional decreases in the hematopoietic syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76c7f261a7bf6bd8b9e079417cdc00c5
https://europepmc.org/articles/PMC5152679/
https://europepmc.org/articles/PMC5152679/
Autor:
Susan Geyer, Mayumi Maki, Kyoji Furukawa, Tomonori Hayashi, Yoichiro Kusunoki, Alvin Shi, Kengo Yoshida, Kei Nakachi, Hiroko Nagamura, Junko Kajimura, Waka Ohishi, Keiko Sasaki, Ivo D. Shterev, Yiqun Hu, Ana Lustig, Yukari Morishita, Seishi Kyoizumi, Nan ping Weng, Ikue Hayashi
Publikováno v:
Oncotarget
Ionizing radiation (IR) is a major source of cellular damage and the immediate cellular response to IR has been well characterized. But the long-term impact of IR on cell function and its relationship with aging are not known. Here, we examined the I