Zobrazeno 41 - 49
of 49
pro vyhledávání: '"Myriam Foglietta"'
Autor:
Sattva S. Neelapu, Tomohide Yamazaki, Laszlo Radvanyi, Myriam Foglietta, Fuliang Chu, Luis M Vence, Seema Rawal, Chen Dong, Wencai Ma, Zhiqiang Wang, Yanli Gao, Durga Nattama, Natalia Martin Orozco, Richard E. Davis
Publikováno v:
Blood. 118:2648-2648
Abstract 2648 Background: Programmed death (PD)-1, a coinhibitory receptor expressed by effector T cells (Teffs) is highly expressed on intratumoral T cells (mean 61%, range 34–86% for CD4+ T cells and mean 44%, range 31–69% for CD8+ T cells) in
Autor:
Kui Voo, Myriam Foglietta, Megan Harlin, Laura Bover, Larry Kwak, Yong-Jun Liu, Sattva Neelapu
Publikováno v:
The Journal of Immunology. 186:156.11-156.11
Active immunotherapy is a promising approach for the treatment of follicular lymphoma (FL), an incurable B-cell lymphoma that accounts for 22% of all non-Hodgkin’s lymphomas worldwide. However, the clinical response rates following therapeutic canc
Autor:
Francesca Pantaleoni, Candida Vitale, Massimo Massaia, Amalia Bosia, Marta Coscia, Sabina Chiaretti, Robin Foà, Mario Boccadoro, Myriam Foglietta, Jean-Jacques Fournié, Silvia Peola, Daniela F. Angelini, Giorgia Matta, Luca Battistini, Marco Ladetto, Daniela Drandi, Chiara Riganti, Anna Guarini
Publikováno v:
Blood. 116:3602-3602
Abstract 3602 The clinical course of chronic lymphocytic leukemia (CLL) depends on the intrinsic tumor cell features but also on the interactions between tumor cells, local microenvironment and host immunity. The interplay between CLL cells and conve
Autor:
Sattva S. Neelapu, Hyun Jun Park, Myriam Foglietta, Durga Nattamai, Seema Rawal, Tina Chou, Shibichakravarthy Kannan
Publikováno v:
Cancer Research. 70:1908-1908
Immunosuppressive Foxp3+ regulatory T cells (Tregs) were shown to be markedly increased in the tumor microenvironment in patients with B-cell non-Hodgkin lymphomas and may impair the efficacy of immunotherapeutic strategies. While the induction of Tr
Autor:
Sattva S. Neelapu, Hong Qin, Myriam Foglietta, Fuliang Chu, Rinat Rotem-Yehudar, Rakesh Sharma, Qing Yi, Galina Rodionov
Publikováno v:
Blood. 114:724-724
Abstract 724 Background: Programmed death (PD)–1 is an inhibitory receptor that impairs the function of activated T-cells and natural killer (NK) cells when engaged by its ligands PD-L1 or PD-L2. We have previously demonstrated that PD-1 is markedl
Autor:
Sattva S. Neelapu, Larry W. Kwak, Myriam Foglietta, Michael R. Bishop, Daniel H. Fowler, Seth M. Steinberg
Publikováno v:
Blood. 114:2250-2250
Abstract 2250 Poster Board II-227 Background: Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative treatment for multiple myeloma (MM) due to its graft-versus-myeloma effect. The use of reduced-intensity conditioning reg
Publikováno v:
Blood. 112:3778-3778
Follicular lymphoma (FL) is one of the most immune responsive of all human malignancies. However, immunoregulatory mechanisms in the tumor microenvironment may impair the efficacy of endogenous immunity as well as therapeutic vaccines and adoptive T-
Autor:
Myriam Foglietta, Jean-Jacques Fournié, Sabina Chiaretti, Massimo Massaia, Francesca Pantaleoni, Amalia Bosia, Chiara Riganti, Giorgia Matta, Luca Battistini, Silvia Peola, Robin Foà, Daniela F. Angelini, Daniela Drandi, Marta Coscia, Mario Boccadoro, Anna Guarini, Marco Ladetto
Publikováno v:
Blood. 110:1131-1131
Vγ9/Vδ2 (γδ) T cells have an important effector and regulatory role in innate and adaptive immunity against microbes, stressed cells and tumor cells. They represent less than 5% of peripheral blood lymphocytes, but can be activated and expanded i
Autor:
Barbara Castella, Sara Mariani, Mario Boccadoro, Myriam Foglietta, Serena Zappia, Laura Godio, Massimo Massaia, Marta Coscia
Publikováno v:
Blood. 108:658-658
Naturally occurring CD4+CD25+ T regulatory cells (Tregs) are a subpopulation of CD4+ T cells playing a key role in lymphocyte homeostasis and maintenance of tolerance. Tregs play a key role in hampering anti-tumor immune surveillance by regulating im