Zobrazeno 101 - 110
of 485
pro vyhledávání: '"Mingyao, Li"'
Recent developments in spatial transcriptomics (ST) technologies have enabled the profiling of transcriptome-wide gene expression while retaining the location information of measured genes within tissues. Moreover, the corresponding high-resolution h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::004febed10031426e7e617e8c2f6fcaa
https://doi.org/10.1101/2021.11.28.470212
https://doi.org/10.1101/2021.11.28.470212
Autor:
Chani J. Hodonsky, Alexandra V. Ligay, Gary K. Owens, Michal Mokry, Bohdan B. Khomtchouk, Huize Pan, Katherine Owsiany, Clint L. Miller, Adam W. Turner, Nelson B. Barrientos, David Mai, Lotte Slenders, Wei Feng Ma, Gabriel F. Alencar, Yipei Song, Mingyao Li, Muredach P. Reilly, Doris Wong, Gerard Pasterkamp, Sander W. van der Laan, Christina A. Gancayco, Jose Verdezoto Mosquera
Publikováno v:
Atherosclerosis
Background and aims The atherosclerotic plaque microenvironment is highly complex, and selective agents that modulate plaque stability are not yet available. We sought to develop a scRNA-seq analysis workflow to investigate this environment and uncov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e020cb2e04a1bd1f3d1332eb6f76e77
https://europepmc.org/articles/PMC8919504/
https://europepmc.org/articles/PMC8919504/
Autor:
Richard Aplenc, Hossein Fazelinia, Benjamin A. Garcia, Joseph Cesare, Olga Shestova, Kathrin M. Bernt, Tina Glisovic-Aplenc, Kevin Nestler, Yang Xu, Yi Xing, Saar Gill, Lusha Cao, Hyoungjoo Lee, Congcong Lu, Asif Chinwalla, Mingyao Li
Publikováno v:
Journal of proteome research. 20(11)
With the rapid developments in mass spectrometry (MS)-based proteomics methods, label-free semiquantitative proteomics has become an increasingly popular tool for profiling global protein abundances in an unbiased manner. However, the reproducibility
Publikováno v:
Genome Res
The advent and rapid development of single-cell technologies have made it possible to study cellular heterogeneity at an unprecedented resolution and scale. Cellular heterogeneity underlies phenotypic differences among individuals, and studying cellu
Autor:
Robert J. Brown, Andrew C. Edmondson, Nathalie Griffon, Theophelus B. Hill, Ilia V. Fuki, Karen O. Badellino, Mingyao Li, Megan L. Wolfe, Muredach P. Reilly, Daniel J. Rader
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 9, Pp 1910-1916 (2009)
Human endothelial lipase (EL) is a member of a family of lipases and phospholipases that are involved in the metabolism of plasma lipoproteins. EL displays a preference to hydrolyze lipids in HDL. We report here that a naturally occurring low frequen
Externí odkaz:
https://doaj.org/article/7d10c1539f4b4dbfbbb22ffceaeed144
Autor:
Junnan Wu, Xin Sheng, Chengxiang Qiu, Todd L. Edwards, Matthew J. Seasock, Thomas M. Coffman, Katalin Susztak, Steven Vitale, Christopher D. Brown, Jacklyn N. Hellwege, Matthew Palmer, Yuting Guan, Kevin L. Duffin, Benjamin F. Voight, Adriana M. Hung, Mingyao Li, Myung K. Shin, Hongbo Liu, Zhen Miao, Ziyuan Ma, Steven S. Pullen
Publikováno v:
Nat Genet
The functional interpretation of genome-wide association studies (GWAS) is challenging due to the cell-type-dependent influences of genetic variants. Here, we generated comprehensive maps of expression quantitative trait loci (eQTLs) for 659 microdis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::811c90ea7197028fb174cd66634d8857
https://europepmc.org/articles/PMC9338440/
https://europepmc.org/articles/PMC9338440/
Autor:
George Cotsarelis, Mingyao Li, Christian Hopkins, B. Kim, Jian Hu, Ruth Choa, Patrick Seale, Elizabeth A. Jacobsen, Arben Nace, John T. Seykora, Andy J. Minn, Mariko Okumura, Zoltan Arany, Garret A. FitzGerald, Shogo Wada, Hu Meng, Taku Kambayashi, Tanner F. Robertson, Ruth-Anne Langan Pai, Malay Haldar, Edward M. Behrens, Rebecca M. May, Junichiro Tohyama
Publikováno v:
Science
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Sweat out the fat with TSLP! Thymic stromal lymphopoietin (TSLP) is a cytokine that can promote immune responses that characterize allergic diseases. Choa et al . found that mice engineered to produce elevated TSLP displayed selective white adipose t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28009fce04a3ca9d720ff5e80907927c
https://europepmc.org/articles/PMC8917823/
https://europepmc.org/articles/PMC8917823/
Autor:
Lea F. Surrey, J. C. Ricarte-Filho, Theodore W. Laetsch, Z. Jones, Mingyao Li, Ken Kazahaya, Andrew J. Bauer, J. C. DeHart, Aime T. Franco, Deanne Taylor, N. S. Adzick, N. Jain, Sogol Mostoufi-Moab, Erin R. Reichenberger, Amber Isaza
BackgroundIn 2014, data from a comprehensive multiplatform analysis of 496 adult papillary thyroid cancer samples reported by The Cancer Genome Atlas project suggested that reclassification of thyroid cancer into molecular subtypes, RAS-like and BRAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac135fe1da8814e85c207137271259b8
https://doi.org/10.1101/2021.07.23.453235
https://doi.org/10.1101/2021.07.23.453235
Publikováno v:
Cancer Research. 82:1218-1218
Recent developments in spatially resolved transcriptomics (SRT) technologies have enabled the profiling of transcriptome-wide gene expression while retaining spatial location information of each measured spot within a tissue. Meanwhile, the correspon
Publikováno v:
Cancer Research. 82:747-747
The tumor microenvironment (TME) contains networks of cells and structures that surround tumor cells. Cell populations in the TME, including their abundance, composition, and spatial location are critical determinants of the occurrence, growth, and m