Zobrazeno 41 - 50
of 236
pro vyhledávání: '"Michel Laviolette"'
Autor:
Michel Laviolette, Isabelle Dubuc, Anne-Sophie Archambault, Amine El Hassani, Amine Cheikh, Étienne Doré, Younes Zaid, Hakima Fares, Louis Flamand, Cyril Martin, Eric Boilard, Volatiana Rakotoarivelo, Youssef Amar, Y. Tijani, Nicolas Flamand
BACKGROUNDSevere Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is the infectious agent responsible for Coronavirus disease 2019 (COVID-19). While SARS-CoV-2 infections are often benign, there are also severe COVID-19 cases, characterized by s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb06fa722131d61a584b2bb97628f53
https://doi.org/10.1101/2020.12.04.20242115
https://doi.org/10.1101/2020.12.04.20242115
Autor:
Jennifer Lamothe, Krystelle Godbout, Aida Eslami, Kim Valette, David C. Nickle, Arnaud Chignon, Andréanne Côté, Maarten van den Berge, Don D. Sin, Patrick Mathieu, Michel Laviolette, Zhonglin Li, Valentin Bon-Baret, Ke Hao, Yohan Bossé, Nathalie Gaudreault, Catherine Labbé, Jean-Christophe Bérubé, Philippe Joubert, Ma'en Obeidat, Sébastien Thériault, Louis-Philippe Boulet, Wim Timens
To identify susceptibility loci and candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mappin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5dfe91f5e9c57dbf62c71df0df0cea
https://doi.org/10.21203/rs.3.rs-68257/v1
https://doi.org/10.21203/rs.3.rs-68257/v1
Autor:
Ma'en Obeidat, Krystelle Godbout, Kim Valette, Philippe Joubert, Louis-Philippe Boulet, Sébastien Thériault, Maarten van den Berge, Patrick Mathieu, Arnaud Chignon, Catherine Labbé, Valentin Bon-Baret, Jean-Christophe Bérubé, Jennifer Lamothe, Nathalie Gaudreault, Aida Eslami, David C. Nickle, Ke Hao, Don D. Sin, Zhonglin Li, Michel Laviolette, Wim Timens, Andréanne Côté, Yohan Bossé
Publikováno v:
Communications Biology
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Communications biology, 4(1):700. Nature Publishing Group
To identify candidate causal genes of asthma, we performed a genome-wide association study (GWAS) in UK Biobank on a broad asthma definition (n = 56,167 asthma cases and 352,255 controls). We then carried out functional mapping through transcriptome-
Autor:
Michel Laviolette, Anne-Sophie Archambault, Alain Veilleux, Keiko Yamamoto, Elyse Y. Bissonnette, Marie-Renée Blanchet, Caroline Turcotte, Vincenzo Di Marzo, Cyril Martin, Élizabeth Dumais, Nami Ohashi, Nicolas Flamand, Louis-Philippe Boulet, Toshimasa Itoh
Publikováno v:
The FASEB journal 34 (2020): 4253–4265. doi:10.1096/fj.201902916R
info:cnr-pdr/source/autori:Turcotte, Caroline; Archambault, Anne-Sophie; Dumais, Elizabeth; Martin, Cyril; Blanchet, Marie-Renee; Bissonnette, Elyse; Ohashi, Nami; Yamamoto, Keiko; Itoh, Toshimasa; Laviolette, Michel; Veilleux, Alain; Boulet, Louis-Philippe; Di Marzo, Vincenzo; Flamand, Nicolas/titolo:Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes/doi:10.1096%2Ffj.201902916R/rivista:The FASEB journal/anno:2020/pagina_da:4253/pagina_a:4265/intervallo_pagine:4253–4265/volume:34
info:cnr-pdr/source/autori:Turcotte, Caroline; Archambault, Anne-Sophie; Dumais, Elizabeth; Martin, Cyril; Blanchet, Marie-Renee; Bissonnette, Elyse; Ohashi, Nami; Yamamoto, Keiko; Itoh, Toshimasa; Laviolette, Michel; Veilleux, Alain; Boulet, Louis-Philippe; Di Marzo, Vincenzo; Flamand, Nicolas/titolo:Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes/doi:10.1096%2Ffj.201902916R/rivista:The FASEB journal/anno:2020/pagina_da:4253/pagina_a:4265/intervallo_pagine:4253–4265/volume:34
The endocannabinoid (eCB) 2-arachidonoyl-gycerol (2-AG) modulates immune responses by activating cannabinoid receptors or through its multiple metabolites, notably eicosanoids. Thus, 2-AG hydrolysis inhibition might represent an interesting anti-infl
Autor:
Michel Laviolette, Daiana Stolz, Peter I. Bonta, Jamila Chakir, Marina Pretolani, Christopher E. Brightling, Michel Aubier, Mario Castro, Rekha Chaudhuri, Desiree Schumann, Latifa Chachi, Peter H. Howarth, Pascal Chanez, Jouke T. Annema, Amisha Singapuri, Richard J. Russell
Publikováno v:
Airway pharmacology and treatment.
Background: Bronchial Thermoplasty (BT) reduces exacerbations and improves asthma quality of life questionnaire (AQLQ) scores in asthma [1]. Studies have shown reductions in airway smooth muscle (ASM) mass and reticular basement membrane (RBM) thickn
Autor:
Michael Simoff, Michel Laviolette, Charlene McEvoy, Jussara Fiterman, Rekha Chaudhuri, Richard G. Barbers, Adalberto Sperb Rubin, José Roberto Lapa e Silva, Salman Siddiqui, Robert Niven, Pallav L. Shah, Frances Nolan, Sumita Khatri, Ronald Olivenstein, David Duhamel, Karin Klooster, Kaharu Sumino
Publikováno v:
Airway pharmacology and treatment.
Background: BT is an endoscopic treatment for uncontrolled asthma. The long-term efficacy and safety of BT beyond 5 years is not known. Objective: To evaluate the efficacy and safety of BT at 10+ years follow-up. Methods: BT10+ is an international, m
Autor:
Michel Laviolette, Delphine Gras, Simon Martel, Ikhlass Haj Salem, Philippe Joubert, Noel Lampron, Pascal Chanez, Louis-Philippe Boulet, Jamila Chakir, Krystelle Godbout
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 199:536-538
Autor:
Michel Laviolette, Isabelle Dubuc, Younes Zaid, Nicolas Flamand, Louis Flamand, Olivier Flamand, Anne Sophie Archambault, Étienne Doré, Eric Boilard
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can lead to a variety of clinical outcomes ranging from the absence of symptoms to severe acute respiratory disease and ultimately death. A feature of patients with sev
Autor:
J. Mark FitzGerald, Richard Leigh, Joel N. Kline, Stephen Lam, Matthew J. Loza, Andreas Eich, Frédéric Baribaud, Patrick Berger, P. Chanez, Philip E. Silkoff, Dave Singh, Vedrana S. Susulic, Steven G. Kelsen, Elliot S. Barnathan, Michel Laviolette, Azra Hussaini, Irina Strambu, William J. Calhoun, Andrea Ludwig-Sengpiel, Geoffrey Chupp, Mark T. Dransfield, Vibeke Backer, Pierre Olivier Girodet, Celeste Porsbjerg
Publikováno v:
Journal of Allergy and Clinical Immunology. 140:710-719
Background The Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and severe asthma and nonatopic healthy control subjects. Objective We explored this data set to define type 2 inflammation b
Autor:
Caroline Turcotte, Robert C. Murphy, Cyril Martin, Marie-Renée Blanchet, Michel Laviolette, Nicolas Flamand, David Marsolais, Stéphanie Jean, Simona Zarini
Publikováno v:
The Journal of Immunology. 198:3255-3263
The endocannabinoids 2-arachidonoyl-glycerol and N-arachidonoyl-ethanolamine mediate an array of pro- and anti-inflammatory effects. These effects are related, in part, to their metabolism by eicosanoid biosynthetic enzymes. For example, N-arachidono