Zobrazeno 41 - 50
of 251
pro vyhledávání: '"Michael W. Gray"'
Publikováno v:
Journal of Molecular Biology. 320:727-739
We report evidence of extensive substitutional editing of mitochondrial mRNAs in the dinoflagellate species Pfiesteria piscicida, Prorocentrum minimum and Crypthecodinium cohnii, based on a comparison of genomic and corresponding cDNA sequences deter
Autor:
Michael W. Gray, David H. Price
Publikováno v:
Modification and Editing of RNA
The term "RNA editing" was first coined more than a decade ago to describe the phenomenon of uridine insertion into trypanosomatid mitochondrial transcripts. Unlike mRNAs, transcripts of tRNA and rRNA genes are themselves converted into the functiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d79f620544ec042b46e4c23be06feff
https://doi.org/10.1128/9781555818296.ch16
https://doi.org/10.1128/9781555818296.ch16
Publikováno v:
Journal of proteomics. 109
We present a combined proteomic and bioinformatic investigation of mitochondrial proteins from the amoeboid protist Acanthamoeba castellanii, the first such comprehensive investigation in a free-living member of the supergroup Amoebozoa. This protist
Autor:
Michael W. Gray
Publikováno v:
RNA Biology
I am honored to have been asked to contribute to this memorial issue, although I cannot claim to have known Carl Woese well. Carl’s insights and the discoveries that his research group made over the years certainly stimulated my own research progra
Autor:
Michael W. Gray
Publikováno v:
Molecular Life Sciences ISBN: 9781461464365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea830cff0745b11733358162d603232
https://doi.org/10.1007/978-1-4614-6436-5_110-3
https://doi.org/10.1007/978-1-4614-6436-5_110-3
Autor:
Michael Charette, Michael W. Gray
Publikováno v:
IUBMB Life (International Union of Biochemistry and Molecular Biology: Life). 49:341-351
Pseudouridine (5-ribosyluracil) is a ubiquitous yet enigmatic constituent of structural RNAs (transfer, ribosomal, small nuclear, and small nucleolar). Although pseudouridine (psi) was the first modified nucleoside to be discovered in RNA, and is the
Publikováno v:
Journal of Molecular Biology. 297:381-393
In the ciliate protozoon, Tetrahymena pyriformis, mitochondrial protein-coding genes are highly divergent in sequence, and in a number of cases they lack AUG initiation codons. We asked whether RNA editing might be acting to generate protein sequence
Autor:
Michael W. Gray, Murray N. Schnare
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1490:362-366
U5 snRNAs in trypanosomatid protozoa do not contain the trimethylguanosine cap structures that are often targeted in snRNA isolation procedures. As a result, the trypanosomatids are not well represented in the database of available U5 snRNA sequences
Publikováno v:
Annual Review of Genetics. 33:351-397
▪ Abstract Recent results from ancestral (minimally derived) protists testify to the tremendous diversity of the mitochondrial genome in various eukaryotic lineages, but also reinforce the view that mitochondria, descendants of an endosymbiotic α-
Autor:
Michael W. Gray
Publikováno v:
Current Opinion in Genetics & Development. 9:678-687
Accumulating molecular data, particularly complete organellar genome sequences, continue to advance our understanding of the evolution of mitochondrial and chloroplast DNAs. Although the notion of a single primary origin for each organelle has been r