Zobrazeno 91 - 100
of 184
pro vyhledávání: '"Michael Rusch"'
Autor:
Jingyan Tang, Shuhong Shen, Lijuan Du, Hongye Sun, Fan Yang, Samuel W. Brady, Kohei Hagiwara, John Easton, Michael N. Edmonson, Liqing Tian, Benjamin J. Raphael, Hui Zhang, Benshang Li, Heather L. Mulder, Diane Flasch, Yongjin Li, Ningling Wang, Yanling Liu, Ting-Nien Lin, Xiaotu Ma, Ching-Hon Pui, Xiaofan Zhu, Yingchi Zhang, Bin-Bing S. Zhou, Michael Rusch, Cheng Cheng, Ying Shao, Jingliao Zhang, Yu Liu, Lele Sun, Matthew A. Myers, Jinghui Zhang, James R. Downing, Jun J. Yang
Publikováno v:
Blood. 132:917-917
Introduction Relapsed childhood acute lymphoblastic leukemia (ALL) is a leading cause of cancer-related death in children and has poor prognosis due to acquired drug resistance. However, the clonal evolution leading to drug resistance at ALL relapse
Autor:
Jason Dapper, Michael A. Dyer, Junmin Peng, Heather L. Mulder, Xiang Chen, Xusheng Wang, Michael Rusch, Ji-Hoon Cho, Elizabeth Stewart, Alberto S. Pappo, Hong Wang, Victoria Honnell, Yuxin Li, Jinghui Zhang, Xin Zhou, Anang A. Shelat, Elaine R. Mardis, Lyra Griffiths, Michael R. Clay, Kristy Boggs, James R. Downing, Kaley Blankenship, Richard K. Wilson, Pankaj Gupta, Timothy I. Shaw, John Easton, Donald Yergeau, Justina McEvoy, Burgess B. Freeman, Yu Liu, Armita Bahrami, Monica Ocarz, Brittney Gordon, Yanling Yang, Sheila A. Shurtleff, Yiping Fan, Beisi Xu, Jongrye Jeon
Publikováno v:
Cancer Cell. 34:411-426.e19
Summary Personalized cancer therapy targeting somatic mutations in patient tumors is increasingly being incorporated into practice. Other therapeutic vulnerabilities resulting from changes in gene expression due to tumor specific epigenetic perturbat
Autor:
Michael Rusch
Der einstige Herr der Welt, Jodaryon, kommt aus Ägypten zurück – ist aber nur noch ein Schatten seiner selbst. Allerdings verdichtet sich der Verdacht, dass mit ihm irgendetwas nicht stimmt. Die Ereignisse überschlagen sich. Der einstige böse W
Autor:
Jing Ma, Sheila A. Shurtleff, Xiang Chen, David Zhao, Kristy Boggs, Gang Wu, Jinjun Cheng, Lei Wei, Heather L. Mulder, Guangchun Song, Charles Lu, Lucinda Fulton, Erin Hedlund, John Easton, Panduka Nagahawatte, Matthew Parker, Ryan P. Lee, Richard K. Wilson, Chunlao Tang, Kerri Ochoa, James R. Downing, Denise Sheer, Michael Rusch, Claudia P. Miller, Yongjin Li, Cyriac Kandoth, Chandanamali Punchihewa, Elaine R. Mardis, Bo Tang, David W. Ellison, Bhavin Vadodaria, Jianmin Wang, Charles G. Mullighan, Suzanne J. Baker, Richard J. Gilbertson, Ibrahim Qaddoumi, Richard W. Kriwacki, Jared Becksfort, Robert Huether, F.A. Boop, Robert S. Fulton, Jinghui Zhang, Wilda Orisme, David J. Dooling, Amar Gajjar, James Dalton, Li Ding, Ruth G. Tatevossian
Publikováno v:
Nature genetics
The most common pediatric brain tumors are low-grade gliomas (LGGs). We used whole-genome sequencing to identify multiple new genetic alterations involving BRAF, RAF1, FGFR1, MYB, MYBL1 and genes with histone-related functions, including H3F3A and AT
Autor:
Jinghui Zhang, Hans G. Drexler, Deqing Pei, Jared Becksfort, Stephen P. Hunger, Letha A. Phillips, Gordana Raca, Debbie Payne-Turner, Charles Lu, Sheila A. Shurtleff, David J. Dooling, Brent L. Wood, Geoffrey Neale, James R. Downing, Julie M. Gastier-Foster, Wendy Stock, Robert Huether, Paula Marlton, Michael Rusch, Mignon L. Loh, Lucinda Fulton, Samir Patel, Cheng Cheng, Andrew W. Roberts, Matthew Parker, Raul C. Ribeiro, Lei Wei, Ian D. Lewis, Ross A. Dickins, Nyla A. Heerema, Michelle L. Churchman, Ernesto Diaz-Flores, Ching-Hon Pui, Shann Ching Chen, Kerri Ochoa, Jing Ma, David W. Ellison, Linda Holmfeldt, Bhavin Vadodaria, L. Bik To, Michael Walsh, Erin Hedlund, John Easton, Kelly McCastlain, Susan L. Heatley, Guangchun Song, Kristy Boggs, Gang Wu, Robert S. Fulton, Susana C. Raimondi, Richard K. Wilson, Michael J. Borowitz, Sharyn D. Baker, Charles G. Mullighan, Li Ding, Christina D. Drenberg, Yashodhan Tabib, Meenakshi Devidas, Elaine R. Mardis, Andrew J. Carroll, Xiang Chen, Anna Andersson, Mark D. Minden
Publikováno v:
Nature Genetics. 45:242-252
The genetic basis of hypodiploid acute lymphoblastic leukemia (ALL), a subtype of ALL characterized by aneuploidy and poor outcome, is unknown. Genomic profiling of 124 hypodiploid ALL cases, including whole-genome and exome sequencing of 40 cases, i
Autor:
Timothy J. Ley, James R. Downing, Xiaoping Su, Andrea Biondi, Jianmin Wang, Li Ding, Stanley Pounds, Tanja A. Gruber, Matthew Parker, Der Cherng Liang, Heather L. Mulder, Giovanni Cazzaniga, Jeffrey E. Rubnitz, Michael Rusch, Paola Ballerini, John Easton, Hartmut Döhner, Ching-Hon Pui, Ramapriya Ganti, Michael I. Barbato, Sheila A. Shurtleff, Farhad Ravandi, Jinghui Zhang, Richard K. Wilson, Yasuhide Hayashi, Lee Yung Shih, Huy Q. Ta, Ina Radtke, Steven M. Kornblau, Stacey K. Ogden, Amanda Larson Gedman, Anna Andersson, Daisuke Tomizawa, Jayanthi Manne, Vedant Gupta, Swati Ranade, Akio Tawa, Stephen D. Nimer, Shann Ching Chen, Gang Wu, Souichi Adachi, Konstanze Döhner, Lei Shi, Jing Ma, Suresh Marada, Jinjun Dang, Elaine R. Mardis, Hagop M. Kantarjian, Cary Koss
Publikováno v:
Cancer Cell. 22(5):683-697
To define the mutation spectrum in non-Down syndrome acute megkaryoblastic leukemia (non-DS-AMKL), we performed transcriptome sequencing on diagnostic blasts from 14 pediatric patients and validated our findings in a recurrency/validation cohort cons
Autor:
Michael Rusch
Auf der Suche nach einer neuen Bleibe erreichen die Xyloten mit ihren Raumschiffen die Erde. Da diese ihnen einladend erscheint, beschließen sie, kurzerhand die Menschen zu vernichten. Aber ganz so einfach wird die Sache nicht, denn auf der Erde her
Autor:
Michael N. Edmonson, Sheila A. Shurtleff, Erin Hedlund, John Easton, Xueyuan Cao, Guangchun Song, Jeffery M. Klco, Heather L. Mulder, Konstanze Döhner, Li Dong, Yu Liu, Robert Huether, Yongjin Li, Jinghui Zhang, Jeffrey E. Rubnitz, Zhongling Cai, Hartmut Döhner, Kristy Boggs, Evan Parganas, Richard K. Wilson, Joy Nakitandwe, Lucinda Fulton, Tanja A. Gruber, Ina Radtke, Peter Paschka, Elaine R. Mardis, Ching-Hon Pui, Bhavin Vadodaria, Jinjun Cheng, Li Ding, Michael Rusch, Donald Yergeau, James R. Downing, Lars Bullinger, Xiang Chen, Amanda Larson Gedman, Jyh Rong Chao, Jianmin Wang, Stanley Pounds, Anna Andersson, Robert S. Fulton, Gang Wu, Charles G. Mullighan, Jing Ma, Richard F. Schlenk, Michael P. Walsh, Jinjun Dang, Chunxu Qu, Zachary J Faber
Publikováno v:
Nature genetics. 48(12)
Acute myeloid leukemia (AML) comprises a heterogeneous group of leukemias frequently defined by recurrent cytogenetic abnormalities, including rearrangements involving subunits of the core-binding factor (CBF) transcriptional complex. To better under
Autor:
Ruth G. Tatevossian, Richard K. Wilson, James R. Downing, Michael Rusch, Ryan P. Lee, Shuoguo Wang, Heather L. Mulder, Kelly Haupfear, Bo Tang, Kathryn McFadden, Jinghui Zhang, Jared Becksfort, Ji Wen, Daniel J. Brat, Sonika Dahiya, Elaine R. Mardis, F.A. Boop, Paul Klimo, Amar Gajjar, David George, Chandanamali Punchihewa, Teresa Santiago, Arie Perry, John Easton, David W. Ellison, Wilda Orisme, William Konomos, Gang Wu, James Dalton, Ibrahim Qaddoumi, Suzanne J. Baker, V. Peter Collins, Kirti Gupta, Ying Shao, Pankaj Gupta, Luciano Neder Serafini, Hilary Highfield Nickols, Sheila A. Shurtleff, Kristy Boggs, Kathreena M Kurian
Publikováno v:
Acta neuropathologica, vol 131, iss 6
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Low-grade neuroepithelial tumors (LGNTs) are diverse CNS tumors presenting in children and young adults, often with a history of epilepsy. While the genetic profiles of common LGNTs, such as the pilocytic astrocytoma and 'adult-type' diffuse gliomas,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb8423c4c292270e35ebe5acc7c27c86
https://escholarship.org/uc/item/3526g1hj
https://escholarship.org/uc/item/3526g1hj
Autor:
David Finkelstein, Matthew Parker, Jinghui Zhang, Richard J. Gilbertson, Hong Joo Kim, Anderson P. Kanagaraj, Yong-Dong Wang, Deanna M. Patmore, Jennifer Moore, David W. Ellison, J. Paul Taylor, Michael Rusch, Yasmine A. Valentin-Vega
Publikováno v:
Scientific Reports
DDX3X is a DEAD-box RNA helicase that has been implicated in multiple aspects of RNA metabolism including translation initiation and the assembly of stress granules (SGs). Recent genomic studies have reported recurrent DDX3X mutations in numerous tum