Zobrazeno 101 - 110
of 253
pro vyhledávání: '"Michael Meyer-Hermann"'
Ebola, one of the most pathogenic and lethal viruses, repeatedly leads to severe outbreaks with large numbers of casualties. By integration of data of fatal, non-fatal and asymptomatic cases, we developed a mathematical model of the immune response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1571a64b7097145b9e42372c75860e7
Autor:
Nicolas Brieu, Peter Braubach, Michael Meyer-Hermann, Friedrich Feuerhake, Katharina Nekolla, Germain Forestier, Ralf Schönmeyer, Nadine S. Schaadt
Publikováno v:
PLoS computational biology
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 2, p e1007385 (2020)
PLoS Computational Biology, Public Library of Science, 2020, 16 (2), pp.e1007385. ⟨10.1371/journal.pcbi.1007385⟩
PLoS Computational Biology
PLoS Computational Biology, Vol 16, Iss 2, p e1007385 (2020)
PLoS Computational Biology, Public Library of Science, 2020, 16 (2), pp.e1007385. ⟨10.1371/journal.pcbi.1007385⟩
Our aim is to complement observer-dependent approaches of immune cell evaluation in microscopy images with reproducible measures for spatial composition of lymphocytic infiltrates. Analyzing such patterns of inflammation is becoming increasingly impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7352d7380c1d6efb9d0f1bf802130e9
https://hdl.handle.net/10033/622191
https://hdl.handle.net/10033/622191
Autor:
Michael Meyer-Hermann, Khailaie S, Lito A. Papaxenopoulou, Katsoulis-Dimitriou K, Ingo Schmitz, Gang Zhao, Medina E, Haralampos Hatzikirou
SUMMARYStaphylococcus aureus is considered a dangerous pathogen due to its ability to evade the immune system and resist multiple antibiotics. These evasive strategies lead to difficult-to-treat chronic infections and abscesses in internal organs inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08e907b8dfb3d30b1619b7bda0275a30
https://doi.org/10.1101/2020.01.17.910786
https://doi.org/10.1101/2020.01.17.910786
Autor:
Salvatore Valvo, Philippe Robert, Michael L. Dustin, Viveka Mayya, Michael Meyer-Hermann, A Kvalvaag, Anastasios Siokis, Philippos Demetriou
Integrin and small immunoglobulin superfamily (sIGSF) adhesion complexes function physiologically in human immunological synapses (IS) wherein sIGSF complexes form a corolla of microdomains around an integrin ring and secretory core. The corolla recr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7d5e545bc0fe2247f6b37a2a2a27f6
Autor:
Michael Meyer-Hermann
Publikováno v:
SSRN Electronic Journal.
Selection of B cells in germinal center (GC) reactions is pivotal to the generation of high affinity antibodies and memory B cells. Knowledge about B cell selection is limited and lacks global understanding. Here, we use current knowledge on molecula
Autor:
Michael Meyer-Hermann, Philippe Robert
Publikováno v:
SSRN Electronic Journal.
Vaccine development is challenged by the hierarchy of immunodominance between the target antigens’ epitopes, and the appearance of antigenic variants by pathogen mutation. The strength and breath of antibody responses relies on selection and mutati
Publikováno v:
The Art of Theoretical Biology ISBN: 9783030334703
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbca8f16c068a39b6d413497f7d740d3
https://doi.org/10.1007/978-3-030-33471-0_37
https://doi.org/10.1007/978-3-030-33471-0_37
Autor:
Michael Meyer-Hermann
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific reports
Scientific Reports
Scientific reports
Rejuvenation of stem cell activity might increase life expectancy by prolonging functionality of organs. Higher stem cell replication rates also bear the risk of cancer. The extent of this risk is not known. While it is difficult to evaluate this can
Publikováno v:
e1008428
PLoS computational biology
United States
PLoS Computational Biology, Vol 16, Iss 12, p e1008428 (2020)
PLoS Computational Biology
PLoS computational biology
United States
PLoS Computational Biology, Vol 16, Iss 12, p e1008428 (2020)
PLoS Computational Biology
In vivo imaging of cytotoxic T lymphocyte (CTL) killing activity revealed that infected cells have a higher observed probability of dying after multiple contacts with CTLs. We developed a three-dimensional agent-based model to discriminate different
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dd1d9330881673e9e574c0b7f4722c8
https://doi.org/10.1101/830505
https://doi.org/10.1101/830505
Autor:
Torsten Witte, Martin Messerle, Andreas Schneider, Johannes Koenig, Sebastian J. Theobald, Michael Mach, Matthias Ballmaier, Simon Danisch, Henning Olbrich, Renata Stripecke, Agnes Bonifacius, Lutz Gieselmann, Constanca Figueiredo, Michael Meyer-Hermann, Meryem S. Ercanoglu, Constantin von Kaisenberg, Frank Klawonn, Britta Eiz-Vesper, Florian Klein, Marija Backovic, Christoph Kreer, Sahamoddin Khailaie, Valery Volk
Publikováno v:
PLoS Pathogens
PLoS Pathogens, 2020, 16 (7), pp.e1008560. ⟨10.1371/journal.ppat.1008560⟩
e1008560
PLoS pathogens
United States
PLoS Pathog
PLoS Pathogens, Vol 16, Iss 7, p e1008560 (2020)
PLoS Pathogens, Public Library of Science, 2020, 16 (7), pp.e1008560. ⟨10.1371/journal.ppat.1008560⟩
PLoS Pathogens, 2020, 16 (7), pp.e1008560. ⟨10.1371/journal.ppat.1008560⟩
e1008560
PLoS pathogens
United States
PLoS Pathog
PLoS Pathogens, Vol 16, Iss 7, p e1008560 (2020)
PLoS Pathogens, Public Library of Science, 2020, 16 (7), pp.e1008560. ⟨10.1371/journal.ppat.1008560⟩
Human cytomegalovirus (HCMV) causes serious complications to immune compromised hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor, interferon-alpha and HCMV-gB were developed to promote de novo antiviral adapt