Zobrazeno 71 - 80
of 1 117
pro vyhledávání: '"Michael J. Owens"'
Autor:
James C. Ritchie, Zachary N. Stowe, Ada M. Loughhead, Angela D. Fisher, Michael J. Owens, C. Lindsay DeVane, D. Jeffrey Newport
Publikováno v:
American Journal of Psychiatry. 163:145-147
Objective: The authors’ goal was to determine the concentration of antidepressants in amniotic fluid during maternal treatment of depression. Method: Women treated with antidepressants undergoing amniocentesis for obstetrical reasons were enrolled.
Publikováno v:
Molecular Pharmacology. 52:571-581
The glucocorticoid receptor (GR) is a ligand-regulated transcription factor that in its unactivated form resides primarily in the cytoplasm. After being bound by steroid, the GR undergoes a conformational change and translocates to the nucleus, where
Autor:
Clinton D. Kilts, Michael J. Owens, Jacque C. Landry, Zachary N. Stowe, Charles B. Nemeroff, Timothy D. Ely, Alexis Llewellyn
Publikováno v:
American Journal of Psychiatry. 154:1255-1260
Objective: The purpose of this study was to determine the concentrations of sertraline and desmethylsertraline in both human breast milk and infant serum. Method: Breast milk samples from 12 women were collected at specific time intervals after oral
Publikováno v:
The Neuroscientist. 3:186-194
Corticotropin-releasing factor (CRF), a 41 amino acid-containing neuropeptide, acts both as a hypothalamic releasing factor, controlling ACTH and corticosteroid secretion, and at extrahypothalamic CNS sites to mod ulate mammalian organisms' responses
Autor:
Steven M. Southwick, J. Douglas Bremner, Dennis S. Charney, Adam Darnell, John H. Krystal, Charles B. Nemeroff, Michael J. Owens, Julio Licinio
Publikováno v:
ResearcherID
Corticotropin-releasing factor (CRF) plays an important role in mediating the mammalian stress response (1). CRF released during stress (2) from nerve terminals originating in the paraventricular nucleus of the hypothalamus increases the secretion of
Publikováno v:
Journal of pharmacological and toxicological methods. 68(2)
Introduction Retrodialysis, as used in neuropharmacological research, is a technique for in vivo delivery of neuroactive agents with concurrent monitoring of their effects on cellular activity with a separation between certain degree of spatial and t
Autor:
Swati M. Rogers, Zachary N. Stowe, Katherine A. Boss-Williams, Chase H. Bourke, Megan L. Yu, Jay M. Weiss, Catherine F. Capello, Michael J. Owens
A rigorously investigated model of stress and antidepressant administration during pregnancy is needed to evaluate possible effects on the mother.The objective of this study was to develop a model of clinically relevant prenatal exposure to an antide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e76e61725d668bfe140060cd3e00d6a
https://europepmc.org/articles/PMC3963147/
https://europepmc.org/articles/PMC3963147/
Publikováno v:
Annals of the New York Academy of Sciences. 780:96-105
Autor:
Jack M. Gorman, Michael J. Owens, Steven Friedman, Leonard A. Rosenblum, Charles B. Nemeroff, Michael W. Andrews, Jeremy D. Coplan
Publikováno v:
Proceedings of the National Academy of Sciences. 93:1619-1623
There is increasing evidence for an important role of adverse early experience on the development of major psychiatric disorders in adulthood. Corticotropin-releasing factor (CRF), an endogenous neuropeptide, is the primary physiological regulator of
Autor:
Michael J. Owens
Publikováno v:
Depression and Anxiety. 4:153-159
The mechanism of action of the antidepressants was reviewed through the summer of 1995. Antagonism of monoamine transport is the primary cellular action associated with many antidepressant medications. However, an increased synaptic concentration of