Zobrazeno 81 - 90
of 260
pro vyhledávání: '"Michael C. Phillips"'
Autor:
Hiroyuki Saito, Kevin J. Pearson, W. Sean Davidson, Patrick Tso, Stephen C. Woods, Michael C. Phillips, Sissel Lund-Katz
Publikováno v:
Biochemistry. 43:10719-10729
Apolipoprotein A-IV (apoA-IV) is an exchangeable apolipoprotein that shares many functional similarities with related apolipoproteins such as apoE and apoA-I but has also been implicated as a circulating satiety factor. However, despite the fact that
Publikováno v:
Progress in Lipid Research. 43:350-380
Exchangeable apolipoproteins function in lipid transport as structural components of lipoprotein particles, cofactors for enzymes and ligands for cell-surface receptors. Recent findings with apoA-I and apoE suggest that the tertiary structures of the
Autor:
Carmel M. Quinn, Gerd Assmann, Mayakonda N. Palgunachari, Dimitri Sviridov, Janelle Wright, John R. Burnett, Gattadahalli M. Anantharamaiah, Kerry-Anne Rye, Ying Fu, Maaike Kockx, Sissel Lund Katz, Katharina Gaus, Michael C. Phillips, Leonard Kritharides, Roger T. Dean, Stephan Rust, Timothy Sloane, David R. Sullivan, Wendy Jessup
Publikováno v:
Journal of Biological Chemistry. 279:25966-25977
Apolipoprotein A-I (apoA-I)-mediated cholesterol efflux involves the binding of apoA-I to the plasma membrane via its C terminus and requires cellular ATP-binding cassette transporter (ABCA1) activity. ApoA-I also stimulates secretion of apolipoprote
Autor:
Raquel F. Epand, Matthew A. Kirksey, Alan M. Fogelman, Susan Hama, David W. Garber, Michael C. Phillips, Richard M. Epand, Mayakonda N. Palgunachari, Manjula Chaddha, Jere P. Segrest, Geeta Datta, Gattadahalli M. Anantharamaiah, Sissel Lund-Katz, Mohamad Navab
Publikováno v:
Journal of Biological Chemistry. 279:26509-26517
The apolipoprotein A-I mimetic peptide 4F (Ac-DWFKAFYDKVAEKFKEAF-NH(2)), with four Phe residues on the nonpolar face of the amphipathic alpha-helix, is strongly anti-inflammatory, whereas two 3F analogs (3F(3) and 3F(14)) are not. To understand how c
Autor:
Sissel Lund-Katz, Margery A. Connelly, Stephen T. Thuahnai, Padmaja Dhanasekaran, Margarita de la Llera-Moya, George H. Rothblat, David L. Williams, Michael C. Phillips
Publikováno v:
Journal of Biological Chemistry. 279:12448-12455
Scavenger receptor (SR)-BI catalyzes the selective uptake of cholesteryl ester (CE) from high density lipoprotein (HDL) by a two-step process that involves the following: 1) binding of HDL to the receptor and 2) diffusion of the CE molecules into the
Autor:
Sissel Lund-Katz, Padmaja Dhanasekaran, George H. Rothblat, Papasani V. Subbaiah, Anna E. Bortnick, Margaret Nickel, Lijuan Liu, Michael C. Phillips
Publikováno v:
Journal of Biological Chemistry. 278:42976-42984
The mechanism of formation of high density lipoprotein (HDL) particles by the action of ATP-binding cassette transporter A1 (ABCA1) is not defined completely. To address this issue, we monitored efflux to apoA-I of phosphatidylcholine (PC), sphingomy
Autor:
Michael C. Phillips, Gattadahalli M. Anantharamaiah, Sissel Lund-Katz, Padmaja Dhanasekaran, Mark L. Segall, Karl H. Weisgraber, Faye Baldwin
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 10, Pp 1688-1700 (2002)
We examined the effects of apolipoprotein E (apoE) domain structure and polymorphism on the kinetics of solubilization (clearance) of dimyristoyl-phosphatidylcholine multilamellar vesicles. This second order reaction consisted of two simultaneous kin
Autor:
George H. Rothblat, William J. Johnson, Sissel Lund-Katz, Margaret Nickel, Omar L. Francone, Michael C. Phillips, Paul Holvoet, Kristin Gillotte-Taylor
Publikováno v:
Journal of Biological Chemistry. 277:11811-11820
This study elucidates the factors underlying the enhancement in efflux of human fibroblast unesterified cholesterol and phospholipid (PL) by lipid-free apolipoprotein (apo) A-I that is induced by cholesterol enrichment of the cells. Doubling the unes
Autor:
Michael C. Phillips
Publikováno v:
The Journal of Biological Chemistry
Most types of cells in the body do not express the capability of catabolizing cholesterol, so cholesterol efflux is essential for homeostasis. For instance, macrophages possess four pathways for exporting free (unesterified) cholesterol to extracellu
Autor:
Sissel Lund-Katz, Padmaja Dhanasekaran, Faye Baldwin, Karl H. Weisgraber, Hiroyuki Saito, Michael C. Phillips
Publikováno v:
Journal of Biological Chemistry. 276:40949-40954
Apolipoprotein (apo) E contains two structural domains, a 22-kDa (amino acids 1–191) N-terminal domain and a 10-kDa (amino acids 223–299) C-terminal domain. To better understand apoE-lipid interactions on lipoprotein surfaces, we determined the t