Zobrazeno 91 - 100
of 225
pro vyhledávání: '"Merle A. Sande"'
Publikováno v:
Journal of Infectious Diseases. 156:456-462
We investigated the effect of cefotaxime and chloramphenicol on endotoxin concentrations in cerebrospinal fluid (CSF) and on the development of brain edema in rabbits with Escherichia coli meningitis. Both antibiotics were similarly effective in redu
Autor:
Merle A. Sande, Ralph G. Dacey
Publikováno v:
Antimicrobial Agents and Chemotherapy. 6:437-441
Probenecid may elevate the cerebrospinal fluid (CSF) concentration of penicillin G by inhibiting the excretion of organic acids from CSF. We have studied this phenomenon with various penicillin and cephalosporin derivatives. Penicillin concentrations
Publikováno v:
Infection and Immunity. 40:950-955
The influence of preformed antibody on the induction of experimental Candida albicans endocarditis was investigated by both in vitro and in vivo techniques. Preincubation of C. albicans with immune serum (raised in rabbits by intravenous injection of
Publikováno v:
Journal of Infectious Diseases. 149:980-985
Studies of therapy for experimental pneumonia due to Pseudomonas aeruginosa have failed to document beta-lactam-aminoglycoside synergy for most antibiotics examined, in contrast to results usually observed with pseudomonas infections at other sites.
Publikováno v:
Journal of Clinical Investigation. 68:1381-1384
Bacterial adhesion to the constituents of nonbacterial thrombotic endocarditis (NBTE) is important in the pathogenesis of endocarditis. Subinhibitory concentrations (subMIC) of some antibiotics decrease bacterial adhesion to epithelial cells in vitro
Publikováno v:
The American Journal of Medicine. 84:218-224
A cholestatic syndrome caused by papillary stenosis and sclerosing cholangitis (PS/SC) has been recently described as a complication of the acquired immunodeficiency syndrome (AIDS). Cytomegalovirus has been implicated as an etiologic factor in this
Autor:
Merle A. Sande, Thomas A. Drake
Publikováno v:
Clinical Infectious Diseases. 5:S345-S355
Bactericidal antibiotic activity is necessary for cure of bacterial endocarditis. The animal model of this disease has proved extremely useful for determining the in vivo significance of in vitro observations of antibiotic effect. A review and correl
Autor:
H. R. da Silva, M. A. Lynch, J. M. Freedman, W. M. Scheld, Merle A. Sande, Herminio Souza Rocha, S. H. Hoffman
Publikováno v:
Journal of Infectious Diseases. 148:886-891
Increasing resistance to antibiotics in meningeal pathogens has stimulated a search for new antimicrobial agents for the treatment of bacterial meningitis. Moxalactam penetrates well into infected cerebrospinal fluid (CSF) and is highly active agains
Publikováno v:
Journal of Infectious Diseases. 151:528-534
A study was made of the effects of antibiotics and corticosteroids on parameters that reflect brain dysfunction and potential neurological damage in experimental pneumococcal meningitis in rabbits. Brain water content was 398 +/- 10 g/100 g dry weigh
Publikováno v:
Journal of Clinical Investigation. 66:243-253
Acute bacterial meningitis may be associated with increased intracranial pressure, neurological sequelae such as communicating hydrocephalus, and a slow response to antibiotic therapy. Alterations in cerebrospinal hydrodynamics are at least partially