Zobrazeno 91 - 100
of 146
pro vyhledávání: '"Melody A. Cobleigh"'
Autor:
Melody A. Cobleigh
Publikováno v:
Gynecological Endocrinology. 11:49-51
Hormone replacement therapy (HRT) is traditionally contraindicated in breast cancer survivors. However, recent trends in early detection and treatment have produced larger numbers of cured women who are likely to die of non-cancer causes. They also f
Autor:
Steven Shak, Melody A. Cobleigh, Maureen T. Cronin, Juan Miguel Mosquera, Russell Borchik, Mei-Lan Liu, Michael G. Walker, Pincas Bitterman, Bita Tabesh, Joffre B. Baker
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(24 Pt 1)
Purpose: This study, along with two others, was done to develop the 21-gene Recurrence Score assay (Oncotype DX) that was validated in a subsequent independent study and is used to aid decision making about chemotherapy in estrogen receptor (ER)–po
Autor:
James D. Reimann, P. Kelly Marcom, Maura N. Dickler, Virginia K. Langmuir, Frankie A. Holmes, Melody A. Cobleigh, Louis Fehrenbacher, Linnea I. Chap, Beth Overmoyer, Kathy D. Miller, Hope S. Rugo, Amy P. Sing
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(4)
Purpose This randomized phase III trial compared the efficacy and safety of capecitabine with or without bevacizumab, a monoclonal antibody to vascular endothelial growth factor, in patients with metastatic breast cancer previously treated with an an
Autor:
Julie Gralow, Timothy J. Whelan, Kathleen I. Pritchard, James N. Ingle, Melody A. Cobleigh, Eric P. Winer, Lori J. Goldstein, Eleftherios P. Mamounas, Rowan T. Chlebowski, George P. Browman, Cheryl L. Perkins, Clifford A. Hudis, Richard D. Gelber, Judy Perotti, Amy S. Langer, Stephan B. Edge, Susan Braun, Harold J. Burstein, Antonio C. Wolff, John Bryant, Mark R. Somerfield, Trevor J. Powles
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 23(3)
Purpose To update the 2003 American Society of Clinical Oncology technology assessment on adjuvant use of aromatase inhibitors. Recommendations Based on results from multiple large randomized trials, adjuvant therapy for postmenopausal women with hor
Autor:
Thomas J. Saphner, George W. Sledge, Kathy D. Miller, David M. Waterhouse, Joseph A. Sparano, Melody A. Cobleigh, Anita Rush-Taylor, Susan Galbraith, Tai-Tsang Chen, Antonio C. Wolff
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 10(6)
Purpose: This pilot trial was performed to evaluate the safety, pharmacokinetics and feasibility of incorporating BMS-275291, a matrix metalloproteinase inhibitor (MMPI), into adjuvant breast cancer therapy. Experimental Design: Patients with stage I
Autor:
Melody A. Cobleigh, John C. Somberg
Publikováno v:
American journal of therapeutics. 11(1)
Autor:
Rachel Rabinovitch, Douglas W. Arthur, Kalliopi P. Siziopikou, Thomas B. Julian, Stewart J. Anderson, P Zheng, Melody A. Cobleigh, Norman Wolmark, Eleftherios P. Mamounas
Publikováno v:
Cancer Research. 72:OT1-2
Background: A significant amount of DCIS is ER negative and/or overexpresses HER2. This provides an opportunity to test molecular therapy in DCIS. In xenograft models and cell lines, T boosts RT effectiveness. In T-treated HER2+ patients, apoptosis o
Autor:
William Novotny, Virginia K. Langmuir, Amy Vassel, James D. Reimann, Latrice Haney, Melody A. Cobleigh, Kathy D. Miller, George W. Sledge
Publikováno v:
Seminars in oncology. 30(5 Suppl 16)
Vascular endothelial growth factor promotes angiogenesis, an important mediator of growth and metastasis in human breast cancer. Bevacizumab, a monoclonal antibody to vascular endothelial growth factor, is under investigation as an anti-angiogenic ag
Autor:
David Frame, Melody A. Cobleigh
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(21)
Autor:
Susan Braun, James N. Ingle, Kathleen I. Pritchard, John Bryant, Julie Gralow, Judy Perotti, Lori J. Goldstein, Amy S. Langer, Harold J. Burstein, Stephen B. Edge, Clifford A. Hudis, Timothy J. Whelan, George P. Browman, Trevor J. Powles, Eric P. Winer, Rowan T. Chlebowski, Richard D. Gelber, Melody A. Cobleigh, Eleftherios P. Mamounas
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(13)