Zobrazeno 21 - 30
of 65
pro vyhledávání: '"Mats Gåfvels"'
Autor:
Mats Gåfvels, Yi-Zeng Yang, Ingemar Björkhem, Curt Einarsson, Ulla Andersson, Gösta Eggertsen, John Y.L. Chiang
Publikováno v:
Biochemical and Biophysical Research Communications. 320:1204-1210
Sterol 12α-hydroxylase (CYP8B1) is an obligatory enzyme for the synthesis of cholic acid and regulation of liver bile acid synthesis and intestine cholesterol absorption. The present study evaluates the roles for sterol regulatory element binding pr
Publikováno v:
Journal of Internal Medicine. 255:684-688
Autor:
Lilian Larsson, Mats Gåfvels, Kristina Kannisto, Paolo Parini, Stefan Rehnmark, Gösta Eggertsen, Katharina Slätis, Paul Webb
Publikováno v:
Atherosclerosis. 237(2)
Thyroid hormone reduces plasma cholesterol and increases expression of low-density lipoprotein receptor (LDL-R) in liver, an effect mediated by thyroid receptor β (TRβ). The selective TRβ modulator GC-1 also enhances several steps in reverse chole
Autor:
Pontus Stierna, Jan Carlstedt-Duke, Ulrika Lind, Gösta Eggertsen, Sigbritt Werner, Ann-Charlotte Wikström, Mats Gåfvels, Mini Ruiz, Martin Holtmann, Lennart Nilsson
Publikováno v:
Clinical Endocrinology. 55:363-371
OBJECTIVE Primary glucocorticoid resistance is characterized by decreased sensitivity to cortisol signalling. We have performed genetic analysis of the glucocorticoid receptor (GR) gene in 12 unrelated patients with primary cortisol resistance as def
Publikováno v:
Journal of Biological Chemistry. 276:555-562
The very low density lipoprotein receptor (VLDL-R) binds and internalizes several ligands, including very low density lipoprotein (VLDL), urokinase-type plasminogen activator:plasminogen activator inhibitor type 1 complexes, lipoprotein lipase, and t
Publikováno v:
FEBS Letters. 451:56-62
The very low density lipoprotein receptor is a member of the low density lipoprotein receptor supergene family for which two isoforms have been reported, one lacking and the other containing an O-linked sugar domain. In order to gain insight into the
Autor:
Dudley K. Strickland, Mats Gåfvels, Lennart Nilsson, Bo Angelin, Anders Hamsten, Leena Musakka, K. Ensler, Per Eriksson
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 5, Pp 913-919 (1999)
Karolinska Institutet
Karolinska Institutet
The potential role of the very low density lipo- protein (VLDL) receptor in mediating VLDL-induced plas- minogen activator inhibitor-1 (PAI-1) expression was stud- ied in vitro. Cultured endothelial cells incubated with VLDL showed an increased secre
Autor:
Yi-Zeng Yang, Ingemar Björkhem, Ulla Andersson, Mats Gåfvels, Gösta Eggertsen, Curt Einarsson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1438:167-174
Sterol 12α-hydroxylase (CYP 8B1) is a microsomal cytochrome P450 enzyme involved in bile acid synthesis that is of critical importance for the composition of bile acids formed in the liver. Thyroidectomy of rats caused a more than twofold increase o
Autor:
Mats Gåfvels, Bhanu P. Chowdhary, Ingemar Björkhem, Monica Jansson, Terje Raudsepp, Ulla Andersson, Bengt Persson, Gösta Eggertsen, Maria Olin
Publikováno v:
Genomics. 56:184-196
Sterol 12alpha-hydroxylase (CYP8B1) is a hepatic cytochrome P-450 that controls the ratio of cholic acid over chenodeoxycholic acid in bile and thus controls the solubility of cholesterol. Both the human and the mouse CYP8B1 complementary DNA and gen
Publikováno v:
The American Journal of Pathology. 153:1923-1935
The high-affinity degradation of low-density lipoprotein (LDL) is enhanced 3- to 100-fold in leukemic blood cells from patients with acute myelogenous leukemia (AML), suggesting an increased cellular LDL receptor expression. There are, however, incon