Zobrazeno 101 - 110
of 178
pro vyhledávání: '"Martina Müller-Nurasyid"'
Autor:
Marcus E. Kleber, Raji P. Grewal, Yingchang Lu, Sanghamitra Mohanty, Harry J.G.M. Crijns, Han Sun, Ilkka Seppälä, Jonathan D. Smith, Albert Hofman, Yii-Der Ida Chen, Diane Fatkin, Patrik K. E. Magnusson, Pil Sung Yang, Jari Laurikka, Saman Nazarian, Peter W. Macfarlane, Natalia S. Rost, Sekar Kathiresan, Heribert Schunkert, Sandosh Padmanabhan, Tõnu Esko, Bruno H. Stricker, Rebecca Gutmann, Alfredo José Mansur, Jonathan Rosand, Jesper Hastrup Svendsen, Alvaro Alonso, J. Gustav Smith, Benjamin Neumann, John Barnard, Christopher D. Anderson, Joanna Pera, Samir Saba, Lynne J. Hocking, Siew-Kee Low, Daniel I. Chasman, Patrick T. Ellinor, Nancy L. Pedersen, Stephan B. Felix, Vilmundur Gudnason, Kjell Nikus, Kahraman Tanriverdi, David J. Porteous, Samuel C. Dudley, Clive R. Pullinger, Tamara B. Harris, Barry London, Lorenz Risch, Ruth J. F. Loos, Rainer Malik, Isabelle C. Van Gelder, John F. Carlquist, Lena Refsgaard, Carolina Roselli, Albert Y. Sun, Man Li, Lenore J. Launer, Anders Hamsten, Svati H. Shah, Lin Y. Chen, Martina Müller-Nurasyid, Michiel Rienstra, Kent D. Taylor, Katharina Schramm, Jennifer A. Brody, Honghuang Lin, Eric Boerwinkle, Rozenn N. Lemaitre, Olle Melander, Hugh Calkins, Elsayed Z. Soliman, Moritz F. Sinner, Heather L. Bloom, Nicholas L. Smith, Nada Esa, John W. Cole, Maartje N. Niemeijer, David R. Van Wagoner, Anubha Mahajan, Roopinder K. Sandhu, Henry J. Lin, Jordi Jimenez-Conde, Ian Ford, Eue Keun Choi, Stacey Knight, Scott M. Damrauer, Markku Eskola, Claudia Schurman, Stuart A. Scott, Sara L. Pulit, Raymond Noordam, Mika Kähönen, Jay A. Montgomery, Agnieszka Slowik, Esra Gucuk Ipek, Joylene E. Siland, Lingyao Zeng, Andrew P. Morris, Oscar H. Franco, Bas L.J.H. Kietselaer, Adnan Kastrati, Dan E. Arking, José Eduardo Krieger, J. Wouter Jukema, Stefan Gustafsson, Nathan R. Tucker, Zachary T. Yoneda, Daniel Woo, Winfried März, Lauren Margolin, Uwe Völker, Stefan Kääb, Marju Orho-Melander, Lars Lind, Yoichiro Kamatani, Maris Teder-Laving, Paul M. Ridker, Bradford B. Worrall, Jaemin Shim, Bob Weijs, Ingrid E. Christophersen, Kenneth B. Margulies, James P. Cook, Graciela Delgado, Andrea Natale, Stefan Weiss, Gustav Ahlberg, Jie Huang, Guillaume Paré, M. Benjamin Shoemaker, Marcus Dörr, Arnljot Tveit, Elton A. M. P. Dudink, Thomas P. Cappola, Bruce M. Psaty, Alaa Shalaby, Gregory M. Marcus, Sébastien Thériault, Niek Verweij, Traci M. Bartz, Thorsten Kessler, Michael Morley, Xiuqing Guo, Alexandre C. Pereira, Efthymia Vlachopoulou, Albert V. Smith, Andrea R. V. R. Horimoto, David Conen, Erik Ingelsson, Jie Yao, Raul Weiss, David D. McManus, Michiaki Kubo, Lu-Chen Weng, Michael A. Rosenberg, Nona Sotoodehnia, Jennifer E. Huffman, Hui Nam Pak, Dan M. Roden, Peter Weeke, Joshua C. Bis, Archie Campbell, Marta Ribasés, Renee Johnson, Renate B. Schnabel, Christian M. Shaffer, Krishna G. Aragam, Seung Hoan Choi, André G. Uitterlinden, Morten S. Olesen, Toshihiro Tanaka, Daniel J. Rader, Mina K. Chung, Stella Trompet, Steven A. Lubitz, Martin Dichgans, Peter Almgren, Christine M. Albert, Blair H. Smith, Petra Katschnig-Winter, Joshua C. Denny, Christopher Newton-Cheh, Paulus Kirchhof, Namrata Gupta, Emelia J. Benjamin, Stefanie Aeschbacher, Marja-Liisa Lokki, Jorge A. Wong, Quinn S. Wells, Jussi Hernesniemi, Cecilia M. Lindgren, Mark Chaffin, Kaoru Ito, Jerome I. Rotter, Michael J. Cutler, Kerri L. Wiggins, Maryam Kavousi, Nathan A. Bihlmeyer, Bastiaan Geelhoed, Susan R. Heckbert, Caroline Hayward, Alexander Teumer, Paul L. Huang, Terho Lehtimäki, Juha Sinisalo, John P. Kane, Kirsten Leineweber, Tanja Zeller, Hong Euy Lim, Kathryn L. Lunetta, Brian R. Daniels, Heidi Oellers, Biqi Wang, Pim van der Harst, Peter M. Nilsson, Dawood Darbar, Erwin B. Bottinger, Leo-Pekka Lyytikäinen
Publikováno v:
Nature Genetics, 50(9), 1225-+. Nature Publishing Group
Nature Genetics, 50(9), 1225-1233. Nature Publishing Group
Roselli, C, Chaffin, M, Weng, L-C, Aeschbacher, S, Ahlberg, G & Campbell, A 2018, ' Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation ', Nature Genetics, vol. 50, pp. 1225–1233 . https://doi.org/10.1038/s41588-018-0133-9
Nature Genetics
Nature Genetics, 50(9), 1225
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature genetics 50(9), 1225-1233 (2018). doi:10.1038/s41588-018-0133-9
Nat. Genet. 50, 1225–1233 (2018)
Nature Genetics, 50(9), 1225-1233. Nature Publishing Group
Roselli, C, Chaffin, M, Weng, L-C, Aeschbacher, S, Ahlberg, G & Campbell, A 2018, ' Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation ', Nature Genetics, vol. 50, pp. 1225–1233 . https://doi.org/10.1038/s41588-018-0133-9
Nature Genetics
Nature Genetics, 50(9), 1225
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature genetics 50(9), 1225-1233 (2018). doi:10.1038/s41588-018-0133-9
Nat. Genet. 50, 1225–1233 (2018)
Atrial fibrillation (AF) affects more than 33 million individuals worldwide 1 and has a complex heritability 2 . We conducted the largest meta-analysis of genome-wide association studies (GWAS) for AF to date, consisting of more than half a million i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf529668217fc475bd2fc1a391160e85
https://pure.eur.nl/en/publications/c85488bf-d180-41eb-aa8f-673f87bd2134
https://pure.eur.nl/en/publications/c85488bf-d180-41eb-aa8f-673f87bd2134
Autor:
Niek Verweij, Stephan B. Felix, Ching-Ti Liu, Hao Mei, Martin D. Tobin, Allan Linneberg, Fernando Rivadeneira, Michiel L. Bots, Leo-Pekka Lyytikäinen, Olli T. Raitakari, Thomas Meitinger, Farid Radmanesh, Jeffrey Haessler, Folkert W. Asselbergs, J. Wouter Jukema, Massimo Mangino, Igor Rudan, Christopher P. Nelson, Vilmundur Gudnason, Xiuqing Guo, Yii-Der Ida Chen, Bruce M. Psaty, Marten E. van den Berg, Caroline Hayward, Tim D. Spector, Albert V. Smith, Marco V Perez, Uwe Völker, Nona Sotoodehnia, Tamara B. Harrris, Aaron Isaacs, Pim van der Harst, Nina Mononen, Nilesh J. Samani, Siegfried Perz, Dan E. Arking, Niels Grarup, Arie C. Maan, Steven A. Lubitz, Torben Hansen, Honghuang Lin, Kent D. Taylor, Yalda Jamshidi, Cornelia M. van Duijn, Jennifer E. Huffman, Marcus Dörr, Alison D. Murray, Jan A. Kors, Martina Müller-Nurasyid, Susan R. Heckbert, Jonathan Rosand, Oluf Pedersen, Anna E Dominiczak, Melanie Waldenberger, Paul L. Huang, Jie Yao, Renée de Mutsert, Henry Völzke, Terho Lehtimäki, Elsayed Z. Soliman, Mika Kähönen, Henry J. Lin, Zhijun Xie, Ozren Polašek, Joshua C. Bis, Archie Campbell, Ivana Kolcic, Stella Trompet, André G. Uitterlinden, Bruno H. Stricker, Jette Bork-Jensen, Mark Eijgelsheim, Georg Homuth, Jennifer A. Brody, Patricia B. Munroe, Peter van der Meer, Patrick T. Ellinor, Jørgen K. Kanters, Lenore J. Launer, Dennis O. Mook-Kanamori, Stefan Weiss, Stefan Kääb, Jessica van Setten, Christopher Newton-Cheh, Annette Peters, James G. Wilson, Sandosh Padmanabhan, Jerome I. Rotter, Rudolf A. de Boer, Bram P. Prins, Nathan A. Bihlmeyer, Alvaro Alonso, Leanne M. Hall, J. Marten, Helen R. Warren, Man Li, Thomas R. Austin, Charles Kooperberg, Moritz F. Sinner, Ruifang Li-Gao
Publikováno v:
Bihlmeyer, N A, Brody, J A, Smith, A V, Warren, H R, Lin, H, Isaacs, A, Liu, C-T, Marten, J, Radmanesh, F, Hall, L M, Grarup, N, Mei, H, Müller-Nurasyid, M, Huffman, J E, Verweij, N, Guo, X, Yao, J, Li-Gao, R, van den Berg, M, Weiss, S, Prins, B P, van Setten, J, Haessler, J, Lyytikäinen, L-P, Li, M, Alonso, A, Soliman, E Z, Bis, J C, Austin, T, Chen, Y-D I, Psaty, B M, Harrris, T B, Launer, L J, Padmanabhan, S, Dominiczak, A, Huang, P L, Xie, Z, Ellinor, P T, Kors, J A, Campbell, A, Murray, A D, Nelson, C P, Tobin, M D, Bork-Jensen, J, Hansen, T, Pedersen, O, Linneberg, A, Sinner, M F, Peters, A, Waldenberger, M, Meitinger, T, Perz, S, Kolcic, I, Rudan, I, de Boer, R A, van der Meer, P, Lin, H J, Taylor, K D, de Mutsert, R, Trompet, S, Jukema, J W, Maan, A C, Stricker, B H C, Rivadeneira, F, Uitterlinden, A, Völker, U, Homuth, G, Völzke, H, Felix, S B, Mangino, M, Spector, T D, Bots, M L, Perez, M, Raitakari, O T, Kähönen, M, Mononen, N, Gudnason, V, Munroe, P B, Lubitz, S A, van Duijn, C M, Newton-Cheh, C H, Hayward, C, Rosand, J, Samani, N J, Kanters, J K, Wilson, J G, Kääb, S, Polasek, O, van der Harst, P, Heckbert, S R, Rotter, J I, Mook-Kanamori, D O, Eijgelsheim, M, Dörr, M, Jamshidi, Y, Asselbergs, F W, Kooperberg, C, Lehtimäki, T, Arking, D E & Sotoodehnia, N 2018, ' ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals ', Circulation: Genomic and Precision Medicine, vol. 11, no. 1, pp. e001758 . https://doi.org/10.1161/CIRCGEN.117.001758
Circulation. Genomic and precision medicine, vol 11, iss 1
Circulation: Genomic and Precision Medicine, 11(1)
Circulation: Genomic and Precision Medicine, 11(1). Lippincott Williams and Wilkins Ltd.
Circ. Genom. Precis. Med. 11:e001758 (2018)
Circulation-cardiovascular genetics, 11(1):UNSP e001758. Lippincott Williams & Wilkins
Circ Cardiovasc Genet
Circulation. Genomic and precision medicine, 11(1), e001758. Lippincott Williams and Wilkins Ltd.
Circulation-Cardiovascular Genetics, 11(1):001758. LIPPINCOTT WILLIAMS & WILKINS
Circulation : Cardiovascular Genetics, 11(1):e001758. LIPPINCOTT WILLIAMS & WILKINS
Bihlmeyer, N A, Brody, J A, Smith, A V, Warren, H R, Lin, H, Isaacs, A, Liu, C-T, Marten, J, Radmanesh, F, Hall, L M, Grarup, N, Mei, H, Muller-Nurasyid, M, Huffman, J E, Verweij, N, Guo, X, Yao, J, Li-Gao, R, van den Berg, M, Weiss, S, Prins, B P, van Setten, J, Haessler, J, Lyytikainen, L-P, Li, M, Alonso, A, Soliman, E Z, Bis, J C, Austin, T, Chen, Y-D I, Psaty, B M, Harrris, T B, Launer, L J, Padmanabhan, S, Dominiczak, A, Huang, P L, Xie, Z, Ellinor, P T, Kors, J A, Campbell, A, Murray, A D, Nelson, C P, Tobin, M D, Bork-Jensen, J, Hansen, T, Pedersen, O, Linneberg, A, Sinner, M F, Peters, A & Kanters, J K 2018, ' ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals ', Circulation. Genomic and precision medicine, vol. 11, no. 1, e001758, pp. 1-10 . https://doi.org/10.1161/CIRCGEN.117.001758
Circulation. Genomic and precision medicine, vol 11, iss 1
Circulation: Genomic and Precision Medicine, 11(1)
Circulation: Genomic and Precision Medicine, 11(1). Lippincott Williams and Wilkins Ltd.
Circ. Genom. Precis. Med. 11:e001758 (2018)
Circulation-cardiovascular genetics, 11(1):UNSP e001758. Lippincott Williams & Wilkins
Circ Cardiovasc Genet
Circulation. Genomic and precision medicine, 11(1), e001758. Lippincott Williams and Wilkins Ltd.
Circulation-Cardiovascular Genetics, 11(1):001758. LIPPINCOTT WILLIAMS & WILKINS
Circulation : Cardiovascular Genetics, 11(1):e001758. LIPPINCOTT WILLIAMS & WILKINS
Bihlmeyer, N A, Brody, J A, Smith, A V, Warren, H R, Lin, H, Isaacs, A, Liu, C-T, Marten, J, Radmanesh, F, Hall, L M, Grarup, N, Mei, H, Muller-Nurasyid, M, Huffman, J E, Verweij, N, Guo, X, Yao, J, Li-Gao, R, van den Berg, M, Weiss, S, Prins, B P, van Setten, J, Haessler, J, Lyytikainen, L-P, Li, M, Alonso, A, Soliman, E Z, Bis, J C, Austin, T, Chen, Y-D I, Psaty, B M, Harrris, T B, Launer, L J, Padmanabhan, S, Dominiczak, A, Huang, P L, Xie, Z, Ellinor, P T, Kors, J A, Campbell, A, Murray, A D, Nelson, C P, Tobin, M D, Bork-Jensen, J, Hansen, T, Pedersen, O, Linneberg, A, Sinner, M F, Peters, A & Kanters, J K 2018, ' ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals ', Circulation. Genomic and precision medicine, vol. 11, no. 1, e001758, pp. 1-10 . https://doi.org/10.1161/CIRCGEN.117.001758
Background QT interval, measured through a standard ECG, captures the time it takes for the cardiac ventricles to depolarize and repolarize. JT interval is the component of the QT interval that reflects ventricular repolarization alone. Prolonged QT
Autor:
Ruth J. F. Loos, Alexandre Reymond, Daniele Cusi, Veikko Salomaa, Martina Müller-Nurasyid, Anne B. Newman, Katja Borodulin, Andrew R. Wood, Mika Kähönen, Michael N. Weedon, John C. Chambers, Sébastien Jacquemont, Rachel M. Freathy, Iris M. Heid, Murielle Bochud, Ilja M. Nolte, Aarno Palotie, Thomas Meitinger, Jennifer Kriebel, Harold Snieder, Caroline Hayward, Harri Rissanen, Anna Murray, Timothy M. Frayling, Frank Geller, Mads Melbye, Erika Salvi, Jacques S. Beckmann, Harmen Boers, Mary F. Feitosa, Jorma Viikari, Lude Franke, Wei Ang, Marja-Liisa Lokki, Marcus A. Tuke, Guillaume Lettre, Samuel E. Jones, Jari Lahti, Hannele Mattsson, Tim D. Spector, Aaron McDaid, Nicholas G. Martin, David P. Strachan, Martin D. Tobin, Kaare Christensen, Jessica Tyrrell, Johan G. Eriksson, Saima Afaq, Cristina Venturini, Jaspal S. Kooner, Fernando Rivadeneira, Louise V. Wain, Weihua Zhang, Zoltán Kutalik, Reedik Mägi, Olli T. Raitakari, Joel N. Hirschhorn, Satu Männistö, Nick Shrine, Seppo Koskinen, Robin N Beaumont, Margit Nõukas, Xueping Liu, Yadav Sapkota, Michael A. Province, Thomas T. Perls, Markus Perola, Massimo Mangino, Nicole Schupf, Aurélien Macé, Anders Rosengren, Naomi R. Wray, Katrin Männik, Sarah E. Medland, Aki S. Havulinna, David J. Porteous, Craig E. Pennell, Katherine S. Ruth, Albertine J. Oldehinkel, Petra A. Lenzini, Thomas Hansen, Peter J. van der Most, Thomas W. Winkler, Thomas Sparsø, Markku S. Nieminen, Annette Peters, Mary K. Wojczynski, P Koponen, Patrick Deelen, Dale R. Nyholt, Hanieh Yaghootkar, Erwin P. Bottinger, Juha Sinisalo, Kati Kristiansson, Grant W. Montgomery, Thomas Werge, Terho Lehtimäki, Bjarke Feenstra, Erkki Vartiainen, Eleonora Porcu, Panos Deloukas, Sina Rüeger, Ursula M. Schick, Annamari Lundqvist, Andres Metspalu, Morris A. Swertz
Publikováno v:
Nature communications, vol. 8, no. 1, pp. 744
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, van der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M-L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, 744 . https://doi.org/10.1038/s41467-017-00556-x
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, Van Der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, no. 1, 744 . https://doi.org/10.1038/s41467-017-00556-x
Nature communications 8 (2017). doi:10.1038/s41467-017-00556-x
info:cnr-pdr/source/autori:Mace, Aurelien; Tuke, Marcus A.; Deelen, Patrick; Kristiansson, Kati; Mattsson, Hannele; Noukas, Margit; Sapkota, Yadav; Schick, Ursula; Porcu, Eleonora; Rueger, Sina; McDaid, Aaron F.; Porteous, David; Winkler, Thomas W.; Salvi, Erika; Shrine, Nick; Liu, Xueping; Ang, Wei Q.; Zhang, Weihua; Feitosa, Mary F.; Venturini, Cristina; van der Most, Peter J.; Rosengren, Anders; Wood, Andrew R.; Beaumont, Robin N.; Jones, Samuel E.; Ruth, Katherine S.; Yaghootkar, Hanieh; Tyrrell, Jessica; Havulinna, Aki S.; Boers, Harmen; Magi, Reedik; Kriebel, Jennifer; Mueller-Nurasyid, Martina; Perola, Markus; Nieminen, Markku; Lokki, Marja-Liisa; Kahonen, Mika; Viikari, Jorma S.; Geller, Frank; Lahti, Jari; Palotie, Aarno; Koponen, Paivikki; Lundqvist, Annamari; Rissanen, Harri; Bottinger, Erwin P.; Afaq, Saima; Wojczynski, Mary K.; Lenzini, Petra; Nolte, Ilja M.; Sparso, Thomas; Schupf, Nicole; Christensen, Kaare; Perls, Thomas T.; Newman, Anne B.; Werge, Thomas; Snieder, Harold; Spector, Timothy D.; Chambers, John C.; Koskinen, Seppo; Melbye, Mads; Raitakari, Olli T.; Lehtimaki, Terho; Tobin, Martin D.; Wain, Louise V.; Sinisalo, Juha; Peters, Annette; Meitinger, Thomas; Martin, Nicholas G.; Wray, Naomi R.; Montgomery, Grant W.; Medland, Sarah E.; Swertz, Morris A.; Vartiainen, Erkki; Borodulin, Katja; Mannisto, Satu; Murray, Anna; Bochud, Murielle; Jacquemont, Sebastien; Rivadeneira, Fernando; Hansen, Thomas F.; Oldehinkel, Albertine J.; Mangino, Massimo; Province, Michael A.; Deloukas, Panos; Kooner, Jaspal S.; Freathy, Rachel M.; Pennell, Craig; Feenstra, Bjarke; Strachan, David P.; Lettre, Guillaume; Hirschhorn, Joel; Cusi, Daniele; Heid, Iris M.; Hayward, Caroline; Mannik, Katrin; Beckmann, Jacques S.; Loos, Ruth J. F.; Nyholt, Dale R.; Metspalu, Andres; Eriksson, Johan G.; Weedon, Michael N.; Salomaa, Veikko; Franke, Lude; Reymond, Alexandre; Frayling, Timothy M.; Kutalik, Zoltan/titolo:CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits/doi:10.1038%2Fs41467-017-00556-x/rivista:Nature communications/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Nature Communications
Nature Communications, 8(1):744. Nature Publishing Group
Nat. Commun. 8:744 (2017)
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, van der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M-L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, no. 1, 744 . https://doi.org/10.1038/s41467-017-00556-x
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, van der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M-L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, 744 . https://doi.org/10.1038/s41467-017-00556-x
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, Van Der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, no. 1, 744 . https://doi.org/10.1038/s41467-017-00556-x
Nature communications 8 (2017). doi:10.1038/s41467-017-00556-x
info:cnr-pdr/source/autori:Mace, Aurelien; Tuke, Marcus A.; Deelen, Patrick; Kristiansson, Kati; Mattsson, Hannele; Noukas, Margit; Sapkota, Yadav; Schick, Ursula; Porcu, Eleonora; Rueger, Sina; McDaid, Aaron F.; Porteous, David; Winkler, Thomas W.; Salvi, Erika; Shrine, Nick; Liu, Xueping; Ang, Wei Q.; Zhang, Weihua; Feitosa, Mary F.; Venturini, Cristina; van der Most, Peter J.; Rosengren, Anders; Wood, Andrew R.; Beaumont, Robin N.; Jones, Samuel E.; Ruth, Katherine S.; Yaghootkar, Hanieh; Tyrrell, Jessica; Havulinna, Aki S.; Boers, Harmen; Magi, Reedik; Kriebel, Jennifer; Mueller-Nurasyid, Martina; Perola, Markus; Nieminen, Markku; Lokki, Marja-Liisa; Kahonen, Mika; Viikari, Jorma S.; Geller, Frank; Lahti, Jari; Palotie, Aarno; Koponen, Paivikki; Lundqvist, Annamari; Rissanen, Harri; Bottinger, Erwin P.; Afaq, Saima; Wojczynski, Mary K.; Lenzini, Petra; Nolte, Ilja M.; Sparso, Thomas; Schupf, Nicole; Christensen, Kaare; Perls, Thomas T.; Newman, Anne B.; Werge, Thomas; Snieder, Harold; Spector, Timothy D.; Chambers, John C.; Koskinen, Seppo; Melbye, Mads; Raitakari, Olli T.; Lehtimaki, Terho; Tobin, Martin D.; Wain, Louise V.; Sinisalo, Juha; Peters, Annette; Meitinger, Thomas; Martin, Nicholas G.; Wray, Naomi R.; Montgomery, Grant W.; Medland, Sarah E.; Swertz, Morris A.; Vartiainen, Erkki; Borodulin, Katja; Mannisto, Satu; Murray, Anna; Bochud, Murielle; Jacquemont, Sebastien; Rivadeneira, Fernando; Hansen, Thomas F.; Oldehinkel, Albertine J.; Mangino, Massimo; Province, Michael A.; Deloukas, Panos; Kooner, Jaspal S.; Freathy, Rachel M.; Pennell, Craig; Feenstra, Bjarke; Strachan, David P.; Lettre, Guillaume; Hirschhorn, Joel; Cusi, Daniele; Heid, Iris M.; Hayward, Caroline; Mannik, Katrin; Beckmann, Jacques S.; Loos, Ruth J. F.; Nyholt, Dale R.; Metspalu, Andres; Eriksson, Johan G.; Weedon, Michael N.; Salomaa, Veikko; Franke, Lude; Reymond, Alexandre; Frayling, Timothy M.; Kutalik, Zoltan/titolo:CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits/doi:10.1038%2Fs41467-017-00556-x/rivista:Nature communications/anno:2017/pagina_da:/pagina_a:/intervallo_pagine:/volume:8
Nature Communications
Nature Communications, 8(1):744. Nature Publishing Group
Nat. Commun. 8:744 (2017)
Macé, A, Tuke, M A, Deelen, P, Kristiansson, K, Mattsson, H, Nõukas, M, Sapkota, Y, Schick, U, Porcu, E, Rüeger, S, McDaid, A F, Porteous, D, Winkler, T W, Salvi, E, Shrine, N, Liu, X, Ang, W Q, Zhang, W, Feitosa, M F, Venturini, C, van der Most, P J, Rosengren, A, Wood, A R, Beaumont, R N, Jones, S E, Ruth, K S, Yaghootkar, H, Tyrrell, J, Havulinna, A S, Boers, H, Mägi, R, Kriebel, J, Müller-Nurasyid, M, Perola, M, Nieminen, M, Lokki, M-L, Kähönen, M, Viikari, J S, Geller, F, Lahti, J, Palotie, A, Koponen, P, Lundqvist, A, Rissanen, H, Bottinger, E P, Afaq, S, Wojczynski, M K, Lenzini, P, Nolte, I M, Sparsø, T, Schupf, N, Christensen, K, Perls, T T, Newman, A B, Werge, T, Snieder, H, Spector, T D, Chambers, J C, Koskinen, S, Melbye, M, Raitakari, O T, Lehtimäki, T, Tobin, M D, Wain, L V, Sinisalo, J, Peters, A, Meitinger, T, Martin, N G, Wray, N R, Montgomery, G W, Medland, S E, Swertz, M A, Vartiainen, E, Borodulin, K, Männistö, S, Murray, A, Bochud, M, Jacquemont, S, Rivadeneira, F, Hansen, T F, Oldehinkel, A J, Mangino, M, Province, M A, Deloukas, P, Kooner, J S, Freathy, R M, Pennell, C, Feenstra, B, Strachan, D P, Lettre, G, Hirschhorn, J, Cusi, D, Heid, I M, Hayward, C, Männik, K, Beckmann, J S, Loos, R J F, Nyholt, D R, Metspalu, A, Eriksson, J G, Weedon, M N, Salomaa, V, Franke, L, Reymond, A, Frayling, T M & Kutalik, Z 2017, ' CNV-association meta-analysis in 191,161 European adults reveals new loci associated with anthropometric traits ', Nature Communications, vol. 8, no. 1, 744 . https://doi.org/10.1038/s41467-017-00556-x
There are few examples of robust associations between rare copy number variants (CNVs) and complex continuous human traits. Here we present a large-scale CNV association meta-analysis on anthropometric traits in up to 191,161 adult samples from 26 co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::652dd426e0ac02bfae91f86498d4a0c7
https://serval.unil.ch/resource/serval:BIB_220FBAC01D96.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_220FBAC01D96.P001/REF.pdf
Autor:
David Conen, Bruce M. Psaty, Ingrid E. Christophersen, Olle Melander, Xiuqing Guo, Bruno H. Stricker, Martina Müller-Nurasyid, Gunnar Engström, Emelia J. Benjamin, Joshua C. Bis, Mina K. Chung, Jerome I. Rotter, Bastiaan Geelhoed, Susan R. Heckbert, Elsayed Z. Soliman, Marcus E. Kleber, Mika Kähönen, Alvaro Alonso, Sébastien Thériault, Henry J. Lin, Marcus Dörr, Kjell Nikus, Peter W. Macfarlane, Christine M. Albert, André G. Uitterlinden, Derek Klarin, Ian Ford, John Barnard, Andreas Martinsson, Lynda M. Rose, Lu-Chen Weng, Jie Yao, Nona Sotoodehnia, Tamara B. Harris, Bouwe P. Krijthe, Jan Heeringa, Moritz F. Sinner, Dan M. Roden, Leo-Pekka Lyytikäinen, Jonathan D. Smith, Stephan B. Felix, Uwe Völker, Albert V. Smith, J. Wouter Jukema, Alexander Teumer, David R. Van Wagoner, Patrick T. Ellinor, J. Gustav Smith, Winfried März, Vilmundur Gudnason, Steven A. Lubitz, Graciela E. Delgado, Daniel I. Chasman, Oscar H. Franco, Peter Weeke, M. Benjamin Shoemaker, Pedro L. Teixeira, Stella Trompet, Dan E. Arking, Melanie Waldenberger, Michiel Rienstra, Kent D. Taylor, Joshua C. Denny, Pim van der Harst, Terho Lehtimäki, Lenore J. Launer, Stefan Kääb, Kathryn L. Lunetta, Guillaume Paré, Niek Verweij
Publikováno v:
Scientific Reports, 7:11303. Nature Publishing Group
Scientific reports, vol 7, iss 1
Scientific Reports, 7
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Sci. Rep. 7:11303 (2017)
Scientific reports, vol 7, iss 1
Scientific Reports, 7
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Sci. Rep. 7:11303 (2017)
It is unclear whether genetic markers interact with risk factors to influence atrial fibrillation (AF) risk. We performed genome-wide interaction analyses between genetic variants and age, sex, hypertension, and body mass index in the AFGen Consortiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b50c51f57041389ccb40d76927d56eb
https://eprints.gla.ac.uk/148500/13/148500.pdf
https://eprints.gla.ac.uk/148500/13/148500.pdf
Autor:
Zoltán Kutalik, Joyce Van Meurs, Urmo Võsa, Martina Müller-Nurasyid, Marc Jan Bonder, Michael Stumvoll, Joseph Powell, Kaido Lepik, Michel Nivard, Peter Kovacs, Holger Prokisch, Pärt Peterson, Jenny Van Dongen, Silva Kasela, Kai Kisand, Annique Claringbould, Tarmo Annilo, Joost Verlouw
Publikováno v:
Lepik, K, Annilo, T, Kukuškina, V, Kisand, K, Kutalik, Z, Peterson, P, Peterson, H, eQTLGen Consortium, Boomsma, D I, Nivard, M G & van Dongen, J 2017, ' C-reactive protein upregulates the whole blood expression of CD59-an integrative analysis ', PLoS Computational Biology, vol. 13, no. 9, e1005766, pp. e1005766 . https://doi.org/10.1371/journal.pcbi.1005766
PLoS Computational Biology, Vol 13, Iss 9, p e1005766 (2017)
PLoS Computational Biology, 13(9):e1005766. Public Library of Science
PLOS Computational Biology
PLoS computational biology, vol. 13, no. 9, pp. e1005766
Lepik, K, Annilo, T, Kukuškina, V, Kisand, K, Kutalik, Z, Peterson, P, Peterson, H, eQTLGen Consortium, Penninx, BWJH & Jansen, R 2017, ' C-reactive protein upregulates the whole blood expression of CD59-an integrative analysis ', PLoS Computational Biology, vol. 13, no. 9, e1005766 . https://doi.org/10.1371/journal.pcbi.1005766
PLoS Computational Biology
PLoS Comput. Biol. 13:e1005766 (2017)
PLoS Computational Biology, Vol 13, Iss 9, p e1005766 (2017)
PLoS Computational Biology, 13(9):e1005766. Public Library of Science
PLOS Computational Biology
PLoS computational biology, vol. 13, no. 9, pp. e1005766
Lepik, K, Annilo, T, Kukuškina, V, Kisand, K, Kutalik, Z, Peterson, P, Peterson, H, eQTLGen Consortium, Penninx, BWJH & Jansen, R 2017, ' C-reactive protein upregulates the whole blood expression of CD59-an integrative analysis ', PLoS Computational Biology, vol. 13, no. 9, e1005766 . https://doi.org/10.1371/journal.pcbi.1005766
PLoS Computational Biology
PLoS Comput. Biol. 13:e1005766 (2017)
Elevated C-reactive protein (CRP) concentrations in the blood are associated with acute and chronic infections and inflammation. Nevertheless, the functional role of increased CRP in multiple bacterial and viral infections as well as in chronic infla
Autor:
Sari Koskenmies, Juha Kere, Andreas Ziegler, Jochen Kruppa, Stefan Blankenberg, Nikolaos Patsinakidis, Jennifer Landsberg, Inke R. König, Andre Franke, Wolfgang Lieb, Regine Gläser, Tanja Zeller, Joerg Wenzel, Jaana Panelius, Taina Hasan, Saleh M. Ibrahim, Harald Grallert, Ann-Charlotte Rönn, Annegret Kuhn, Arne Schillert, Martina Müller-Nurasyid, Manfred Kunz, Enno Schmidt, Annamari Ranki, Jan C. Simon, Thomas Tüting
Publikováno v:
Experimental Dermatology. 24:510-515
Cutaneous lupus erythematosus (CLE) is a chronic autoimmune disease of the skin with typical clinical manifestations. Here, we genotyped 906 600 single nucleotide polymorphisms (SNPs) in 183 CLE cases and 1288 controls of Central European ancestry. R
Autor:
Janine Kröger, Konstantin Strauch, Martina Müller-Nurasyid, Karina Meidtner, Heiner Boeing, Matthias B. Schulze, Christian Gieger, Cornelia Prehn, Sapna Sharma, Jerzy Adamski, Susanne Jäger, Anna Floegel, Harald Grallert, Simone Wahl, Annette Peters, Melanie Waldenberger, Per Hoffmann, Karsten Suhre, Tobias Pischon
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Sci. Rep. 7:6037 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Sci. Rep. 7:6037 (2017)
Diabetes-associated metabolites may aid the identification of new risk variants for type 2 diabetes. Using targeted metabolomics within a subsample of the German EPIC-Potsdam study (n = 2500), we tested previously published SNPs for their association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07609678ba12ec50d658df27f1dbda93
http://edoc.mdc-berlin.de/16679/2/16679suppl.pdf
http://edoc.mdc-berlin.de/16679/2/16679suppl.pdf
Autor:
Elior Rahmani, Eran Halperin, Martina Müller-Nurasyid, Omer Weissbrod, Saharon Rosset, Regev Schweiger, Melanie Waldenberger, Sonja Kunze, Christian Gieger
Publikováno v:
Genetics 207, 1275-1283 (2017)
Testing for the existence of variance components in linear mixed models is a fundamental task in many applicative fields. In statistical genetics, the score test has recently become instrumental in the task of testing an association between a set of
Autor:
Joshua C. Bis, Daniel I. Chasman, Archie Campbell, J. Wouter Jukema, Yoichiro Kamatani, Joylene E. Siland, Siegfried Perz, Jie Huang, Jorge A. Wong, Jared W. Magnani, Stefan Weiss, Caroline Hayward, Christopher D. Anderson, Carolina Roselli, Alexander P. Reiner, Maartje N. Niemeijer, Efthymia Vlachopoulou, David R. Van Wagoner, Elsayed Z. Soliman, Lenore J. Launer, Claudia Schurmann, Jeffrey Haessler, Joshua C. Denny, Qiong Yang, Mika Kähönen, Henry J. Lin, Lu-Chen Weng, Molong Li, Paul L. Huang, Terho Lehtimäki, Bruno H. Stricker, Lewin Eisele, Christopher Newton-Cheh, Marcus E. Kleber, Alexander Teumer, Rainer Malik, Juha Sinisalo, Siew-Kee Low, Xiaoyan Yin, Stéphanie Debette, Jennifer A. Brody, Marco V Perez, Derek Klarin, Farid Radmanesh, Ian Ford, Dan M. Roden, Paul M. Ridker, Jan Heeringa, Jonathan Rosand, Andrew P. Morris, Winfried März, Stefan Gustafsson, Xiuqing Guo, Nathan R. Tucker, Dawood Darbar, Daniel J. Rader, Martin Dichgans, Stefan Kääb, Lars Lind, Patrick T. Ellinor, Nancy L. Pedersen, Stefanie Aeschbacher, Erwin B. Bottinger, Leo-Pekka Lyytikäinen, Peter Lichtner, Marcus Dörr, Svati H. Shah, Lin Y. Chen, Alvaro Alonso, Marja-Liisa Lokki, Albert V. Smith, Guillaume Paré, Ruth J. F. Loos, Christine M. Albert, Markku Eskola, Jonathan D. Smith, Kjell Nikus, Martina Müller-Nurasyid, Yanick Hagemeijer, Lorenz Risch, Nona Sotoodehnia, Jussi Hernesniemi, Albert Y. Sun, Man Li, Jemma C. Hopewell, Olle Melander, Albert Hofman, Annette Peters, Pim van der Harst, Michiel Rienstra, Ilkka Seppälä, Kent D. Taylor, Charles Kooperberg, Moritz F. Sinner, Jerome I. Rotter, Stuart A. Scott, Toshihiro Tanaka, Steven A. Lubitz, Uwe Völker, Marju Orho-Melander, Patrik K. E. Magnusson, Jari Laurikka, M. Benjamin Shoemaker, Niek Verweij, J. Gustav Smith, José Eduardo Krieger, Sébastien Thériault, Andrea R. V. R. Horimoto, Natalia S. Rost, André G. Uitterlinden, Oscar H. Franco, David Conen, Cecilia M. Lindgren, Sekar Kathiresan, Michiaki Kubo, Marina Arendt, Graciela Delgado, Anders Hamsten, Rajat Deo, Lars Lannfelt, Sebastian Clauss, Sandosh Padmanabhan, Emelia J. Benjamin, Roopinder K. Sandhu, Bruce M. Psaty, Peter Weeke, Mark Chaffin, Traci M. Bartz, Erik Ingelsson, Alfredo José Mansur, Nathan A. Bihlmeyer, Christian M. Shaffer, Lynne J. Hocking, Stella Trompet, Melanie Waldenberger, Honghuang Lin, Stephan B. Felix, David J. Porteous, Vilmundur Gudnason, Eric Boerwinkle, Dan E. Arking, Alexandre C. Pereira, Bastiaan Geelhoed, Susan R. Heckbert, Jie Yao, Bradford B. Worrall, Ingrid E. Christophersen, Jennifer Kriebel, Peter Almgren, Blair H. Smith, Jennifer E. Huffman, Seung Hoan Choi, Mina K. Chung, Karl-Heinz Jöckel, Yingchang Lu, Yii-Der Ida Chen, Peter W. Macfarlane, John Barnard, Tamara B. Harris, Kathryn L. Lunetta, Stefanie Heilmann-Heimbach, Ganesh Chauhan
Publikováno v:
Nature Genetics, 49(6), 946-+. Nature Publishing Group
Nature Genetics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Genetics, 49(6), 946
Nature Genetics, 49(6), 946-952. Nature Publishing Group
Christophersen, I E, Rienstra, M, Roselli, C, Yin, X, Geelhoed, B, Barnard, J, Lin, H, Arking, D E, Smith, A V, Albert, C M, Chaffin, M, Tucker, N R, Li, M, Klarin, D, Bihlmeyer, N A, Low, S-K, Weeke, P E, Müller-nurasyid, M, Smith, J G, Brody, J A, Niemeijer, M N, Dörr, M, Trompet, S, Huffman, J, Gustafsson, S, Schurmann, C, Kleber, M E, Lyytikäinen, L-P, Seppälä, I, Malik, R, Horimoto, A R V R, Perez, M, Sinisalo, J, Aeschbacher, S, Thériault, S, Yao, J, Radmanesh, F, Weiss, S, Teumer, A, Choi, S H, Weng, L-C, Clauss, S, Deo, R, Rader, D J, Shah, S H, Sun, A, Morris, A P, Campbell, A, Porteous, D & Hayward, C 2017, ' Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation ', Nature Genetics, vol. 49, no. 6, pp. 946-952 . https://doi.org/10.1038/ng.3843
Nat. Genet. 49, 946-952 (2017)
Nature genetics 49(6), 946-952 (2017). doi:10.1038/ng.3843
Nature Genetics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Nature Genetics, 49(6), 946
Nature Genetics, 49(6), 946-952. Nature Publishing Group
Christophersen, I E, Rienstra, M, Roselli, C, Yin, X, Geelhoed, B, Barnard, J, Lin, H, Arking, D E, Smith, A V, Albert, C M, Chaffin, M, Tucker, N R, Li, M, Klarin, D, Bihlmeyer, N A, Low, S-K, Weeke, P E, Müller-nurasyid, M, Smith, J G, Brody, J A, Niemeijer, M N, Dörr, M, Trompet, S, Huffman, J, Gustafsson, S, Schurmann, C, Kleber, M E, Lyytikäinen, L-P, Seppälä, I, Malik, R, Horimoto, A R V R, Perez, M, Sinisalo, J, Aeschbacher, S, Thériault, S, Yao, J, Radmanesh, F, Weiss, S, Teumer, A, Choi, S H, Weng, L-C, Clauss, S, Deo, R, Rader, D J, Shah, S H, Sun, A, Morris, A P, Campbell, A, Porteous, D & Hayward, C 2017, ' Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation ', Nature Genetics, vol. 49, no. 6, pp. 946-952 . https://doi.org/10.1038/ng.3843
Nat. Genet. 49, 946-952 (2017)
Nature genetics 49(6), 946-952 (2017). doi:10.1038/ng.3843
Atrial fibrillation affects more than 33 million people worldwide and increases the risk of stroke, heart failure, and death(1,2). Fourteen genetic loci have been associated with atrial fibrillation in European and Asian ancestry groups(3-7). To furt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a902e450d50126ae57f672430d09f7e
https://hdl.handle.net/1887/95093
https://hdl.handle.net/1887/95093
Autor:
Massimo Mangino, Alison D. Murray, Kathleen Stirrups, Antonella Mulas, Claudia P. Cabrera, Stephan B. Felix, Martin D. Tobin, Jerome I. Rotter, Jan A. Kors, Arno W. Hoes, Bruno H. Stricker, David J. Porteous, Cornelia M. van Duijn, Yi-Ping Fu, George Dedoussis, Ozren Polasek, Nathan A. Bihlmeyer, Ruben N. Eppinga, Marco Orru, Torben Hansen, Elsayed Z. Soliman, James G. Wilson, Martina Müller-Nurasyid, Stefan Weiss, Peter W. Macfarlane, Oluf Pedersen, Honghuang Lin, Joshua C. Bis, Mika Kähönen, Farid Radmanesh, Sandosh Padmanabhan, Xiuqing Guo, Henry J. Lin, Tamara B. Harris, Magdalena Zoledziewska, Nabi Shah, Ilonca Vaartjes, Niels Grarup, Mark J. Caulfield, Yalda Jamshidi, Bram P. Prins, J. Wouter Jukema, Nona Sotoodehnia, Andrew Tinker, Jørgen K. Kanters, Patrick T. Ellinor, Alvaro Alonso, Leanne M. Hall, Helen R. Warren, Man Li, Marcus Dörr, Hugoline G. de Haan, Charles Kooperberg, Moritz F. Sinner, Eleftheria Zeggini, Lihong Qi, Aaron Isaacs, Susan R. Heckbert, Carolina Roselli, Serena Sanna, Bruce M. Psaty, Niek Verweij, Dennis O. Mook-Kanamori, Shih-Jen Hwang, Stefan Kääb, Melanie Waldenberger, Rudolf A. de Boer, Caroline Hayward, Annette Peters, Uwe Völker, Giorgio Pistis, Jeffrey Haessler, Folkert W. Asselbergs, Alex S. F. Doney, Albert V. Smith, Yanick Hagemeijer, Lenore J. Launer, Steven A. Lubitz, Peter S. Sever, André G. Uitterlinden, Jonathan Rosand, Renée de Mutsert, Anna F. Dominiczak, Colin N. A. Palmer, Jennifer A. Brody, Naveed Sattar, Ivana Kolcic, Paul L. Huang, Stella Trompet, Aiman Entwistle, Terho Lehtimäki, Peter van der Meer, Nilesh J. Samani, Alice Stanton, Ruifang Li-Gao, Patricia B. Munroe, Pim van der Harst, Kent D. Taylor, Andrew D. Morris, Igor Rudan, Christopher P. Nelson, Simin Liu, Neil R Poulter, Fernando Rivadeneira, Leo-Pekka Lyytikäinen, Marten E. van den Berg, Allan Linneberg, Zhijun Xie, Claudia Tamar Silva, Jessica van Setten, Jonathan Marten, Jie Yao, Olli T. Raitakari, Christopher J. O'Donnell, Vilmundur Gudnason, Borbala Mifsud, Mark Eijgelsheim, Panos Deloukas, Hao Mei, Tim D. Spector, Dan E. Arking
Publikováno v:
van den Berg, M E, Warren, H R, Cabrera, C P, Verweij, N, Mifsud, B, Haessler, J, Bihlmeyer, N A, Fu, Y-P, Weiss, S, Lin, H J, Grarup, N, Li-Gao, R, Pistis, G, Shah, N, Brody, J A, Müller-Nurasyid, M, Lin, H, Mei, H, Smith, A V, Lyytikäinen, L-P, Hall, L M, van Setten, J, Trompet, S, Prins, B P, Isaacs, A, Radmanesh, F, Marten, J, Entwistle, A, Kors, J A, Silva, C T, Alonso, A, Bis, J C, de Boer, R A, de Haan, H G, de Mutsert, R, Dedoussis, G, Dominiczak, A F, Doney, A S F, Ellinor, P T, Eppinga, R N, Felix, S B, Guo, X, Hagemeijer, Y, Hansen, T, Harris, T B, Heckbert, S R, Huang, P L, Hwang, S-J, Kähönen, M, Kanters, J K, Kolcic, I, Launer, L J, Li, M, Yao, X J, Linneberg, A, Liu, S, Macfarlane, P W, Mangino, M, Morris, A D, Mulas, A, Murray, A D, Nelson, C P, Orrù, M, Padmanabhan, S, Peters, A, Porteous, D J, Poulter, N, Psaty, B M, Qi, L, Raitakari, O T, Rivadeneira, F, Roselli, C, Rudan, I, Sattar, N, Sever, P, Sinner, M F, Soliman, E Z, Spector, T D, Stanton, A V, Stirrups, K E, Taylor, K D, Tobin, M D, Uitterlinden, A, Vaartjes, I, Hoes, A W, van der Meer, P, Völker, U, Waldenberger, M, Xie, Z, Zoledziewska, M, Tinker, A, Polasek, O, Rosand, J, Jamshidi, Y, van Duijn, C M, Zeggini, E, Jukema, J W, Asselbergs, F W, Samani, N J, Lehtimäki, T, Gudnason, V, Wilson, J, Lubitz, S A, Kääb, S, Sotoodehnia, N, Caulfield, M J, Palmer, C N A, Sanna, S, Mook-Kanamori, D O, Deloukas, P, Pedersen, O, Rotter, J I, Dörr, M, O'Donnell, C J, Hayward, C, Arking, D E, Kooperberg, C, van der Harst, P, Eijgelsheim, M, Stricker, B H C & Munroe, P B 2017, ' Discovery of novel heart rate-associated loci using the Exome Chip ', Human Molecular Genetics, vol. 26, no. 12, pp. 2346-2363 . https://doi.org/10.1093/hmg/ddx113
Human Molecular Genetics
Human Molecular Genetics, 26(12), 2346-2363. Oxford University Press
van den Berg, M E, Warren, H R, Cabrera, C P, Verweij, N, Mifsud, B, Haessler, J, Bihlmeyer, N A, Fu, Y-P, Weiss, S, Lin, H J, Grarup, N, Li-Gao, R, Pistis, G, Shah, N, Brody, J A, Müller-Nurasyid, M, Lin, H, Mei, H, Smith, A V, Lyytikäinen, L-P, Hall, L M, van Setten, J, Trompet, S, Prins, B P, Isaacs, A, Radmanesh, F, Marten, J, Entwistle, A, Kors, J A, Silva, C T, Alonso, A, Bis, J C, de Boer, R, de Haan, H G, de Mutsert, R, Dedoussis, G, Dominiczak, A F, Doney, A S F, Ellinor, P T, Eppinga, R N, Felix, S B, Guo, X, Hagemeijer, Y, Hansen, T, Harris, T B, Heckbert, S R, Huang, P L, Hwang, S-J, Kähönen, M, Kanters, J K, Kolcic, I, Launer, L J, Li, M, Yao, J, Linneberg, A, Liu, S, Macfarlane, P W, Mangino, M, Morris, A D, Mulas, A, Murray, A D, Nelson, C P, Orrú, M, Padmanabhan, S, Peters, A, Porteous, D J, Poulter, N, Psaty, B M, Qi, L, Raitakari, O T, Rivadeneira, F, Roselli, C, Rudan, I, Sattar, N, Sever, P, Sinner, M F, Soliman, E Z, Spector, T D, Stanton, A V, Stirrups, K E, Taylor, K D, Tobin, M D, Uitterlinden, A, Vaartjes, I, Hoes, A W, van der Meer, P, Völker, U, Waldenberger, M, Xie, Z, Zoledziewska, M, Tinker, A, Polasek, O, Rosand, J, Jamshidi, Y, van Duijn, C M, Zeggini, E, Wouter Jukema, J, Asselbergs, F W, Samani, N J, Lehtimäki, T, Gudnason, V, Wilson, J, Lubitz, S A, Kääb, S, Sotoodehnia, N, Caulfield, M J, Palmer, C N A, Sanna, S, Mook-Kanamori, D O, Deloukas, P, Pedersen, O, Rotter, J I, Dörr, M, O'Donnell, C J, Hayward, C, Arking, D E, Kooperberg, C, van der Harst, P, Eijgelsheim, M, Stricker, B H & Munroe, P B 2017, ' Discovery of novel heart rate-associated loci using the Exome Chip ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddx113
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Human Molecular Genetics, 26(12), 2346. Oxford University Press
Human Molecular Genetics, 26(12), 2346-2363
Human Molecular Genetics
Human Molecular Genetics, 26(12), 2346-2363. Oxford University Press
van den Berg, M E, Warren, H R, Cabrera, C P, Verweij, N, Mifsud, B, Haessler, J, Bihlmeyer, N A, Fu, Y-P, Weiss, S, Lin, H J, Grarup, N, Li-Gao, R, Pistis, G, Shah, N, Brody, J A, Müller-Nurasyid, M, Lin, H, Mei, H, Smith, A V, Lyytikäinen, L-P, Hall, L M, van Setten, J, Trompet, S, Prins, B P, Isaacs, A, Radmanesh, F, Marten, J, Entwistle, A, Kors, J A, Silva, C T, Alonso, A, Bis, J C, de Boer, R, de Haan, H G, de Mutsert, R, Dedoussis, G, Dominiczak, A F, Doney, A S F, Ellinor, P T, Eppinga, R N, Felix, S B, Guo, X, Hagemeijer, Y, Hansen, T, Harris, T B, Heckbert, S R, Huang, P L, Hwang, S-J, Kähönen, M, Kanters, J K, Kolcic, I, Launer, L J, Li, M, Yao, J, Linneberg, A, Liu, S, Macfarlane, P W, Mangino, M, Morris, A D, Mulas, A, Murray, A D, Nelson, C P, Orrú, M, Padmanabhan, S, Peters, A, Porteous, D J, Poulter, N, Psaty, B M, Qi, L, Raitakari, O T, Rivadeneira, F, Roselli, C, Rudan, I, Sattar, N, Sever, P, Sinner, M F, Soliman, E Z, Spector, T D, Stanton, A V, Stirrups, K E, Taylor, K D, Tobin, M D, Uitterlinden, A, Vaartjes, I, Hoes, A W, van der Meer, P, Völker, U, Waldenberger, M, Xie, Z, Zoledziewska, M, Tinker, A, Polasek, O, Rosand, J, Jamshidi, Y, van Duijn, C M, Zeggini, E, Wouter Jukema, J, Asselbergs, F W, Samani, N J, Lehtimäki, T, Gudnason, V, Wilson, J, Lubitz, S A, Kääb, S, Sotoodehnia, N, Caulfield, M J, Palmer, C N A, Sanna, S, Mook-Kanamori, D O, Deloukas, P, Pedersen, O, Rotter, J I, Dörr, M, O'Donnell, C J, Hayward, C, Arking, D E, Kooperberg, C, van der Harst, P, Eijgelsheim, M, Stricker, B H & Munroe, P B 2017, ' Discovery of novel heart rate-associated loci using the Exome Chip ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddx113
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Human Molecular Genetics, 26(12), 2346. Oxford University Press
Human Molecular Genetics, 26(12), 2346-2363
Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea0e3c62ac114ee25ccdbb7534cb4d7
https://dspace.library.uu.nl/handle/1874/360727
https://dspace.library.uu.nl/handle/1874/360727