Zobrazeno 41 - 50
of 854
pro vyhledávání: '"Martin Bornhäuser"'
Autor:
Jan-Niklas Eckardt, Christoph Röllig, Klaus Metzeler, Michael Kramer, Sebastian Stasik, Julia-Annabell Georgi, Peter Heisig, Karsten Spiekermann, Utz Krug, Jan Braess, Dennis Görlich, Cristina M. Sauerland, Bernhard Woermann, Tobias Herold, Wolfgang E. Berdel, Wolfgang Hiddemann, Frank Kroschinsky, Johannes Schetelig, Uwe Platzbecker, Carsten Müller-Tidow, Tim Sauer, Hubert Serve, Claudia Baldus, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Mathias Hänel, Christoph Schliemann, Maher Hanoun, Christian Thiede, Martin Bornhäuser, Karsten Wendt, Jan Moritz Middeke
Publikováno v:
Haematologica, Vol 108, Iss 3 (2022)
Achievement of complete remission signifies a crucial milestone in the therapy of acute myeloid leukemia (AML) while refractory disease is associated with dismal outcomes. Hence, accurately identifying patients at risk is essential to tailor treatmen
Externí odkaz:
https://doaj.org/article/1a08167ea2bf4756b3b1d34012b7dc50
Autor:
Sabine Kayser, David Martínez-Cuadrón, Maher Hanoun, Friedrich Stölzel, Cristina Gil, H. Christian Reinhardt, Eliana Aguiar, Kerstin Schäfer-Eckart, Juan Miguel Bergua Burgues, Björn Steffen, Teresa Bernal, Stefan W. Krause, Rosalía Riaza, Christoph Schliemann, Jose Cervera, Martin Kaufmann, Laura Torres-Miñana, Mathias Hänel, Evelyn Acuña-Cruz, Edgar Jost, Jesus Lorenzo Algarra, Martina Crysandt, Lars Fransecky, Javier Cornago-Navascues, Sabrina Kraus, Joaquin Martinez-Lopez, Hermann Einsele, Dirk Niemann, Andreas Neubauer, Ruth Seggewiß-Bernhardt, Sebastian Scholl, Stefan A. Klein, Christoph Schmid, Markus Schaich, Martin Schmidt-Hieber, Sven Zukunft, Anthony D. Ho, Uwe Platzbecker, Claudia D. Baldus, Carsten Müller-Tidow, Christian Thiede, Martin Bornhäuser, Hubert Serve, Mark Levis, Pau Montesinos, Christoph Röllig, Richard F. Schlenk
Publikováno v:
Haematologica, Vol 108, Iss 1 (2022)
We retrospectively studied 125 patients with acute myeloid leukemia and trisomy 4 (median age at diagnosis, 58 years; range, 16-77 years) treated between 2000 and 2019 within a multicenter study. Trisomy 4 was the sole abnormality in 28 (22%) patient
Externí odkaz:
https://doaj.org/article/e4e11f5318024c99a75f248fe4ef3498
Autor:
Pascal Fichtel, Malte von Bonin, Robert Kuhnert, Kristin Möbus, Martin Bornhäuser, Manja Wobus
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Aging of the hematopoietic system is characterized by an expansion of hematopoietic stem and progenitor cells (HSPCs) with reduced capacity for engraftment, self-renewal, and lymphoid differentiation, resulting in myeloid-biased hematopoiesis. This p
Externí odkaz:
https://doaj.org/article/e6a155e6f35f4c3492034ce270812d2b
Autor:
Carmine Liberatore, Maria Teresa Lupo Stanghellini, Francesca Lorentino, Luca Vago, Matteo Giovanni Carrabba, Raffaella Greco, Sarah Marktel, Andrea Assanelli, Francesca Farina, Consuelo Corti, Massimo Bernardi, Jacopo Peccatori, Katja Sockel, Jan Moritz Middeke, Johannes Schetelig, Anika Bergmann, Christina Rautenberg, Fabio Ciceri, Martin Bornhäuser, Thomas Schroeder, Friedrich Stölzel
Publikováno v:
Therapeutic Advances in Hematology, Vol 13 (2022)
Introduction: Azacitidine (AZA) either single-agent or with donor lymphocytes infusions (DLI) has been used as a salvage treatment for acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) relapsing after allogeneic hematopoietic stem cell
Externí odkaz:
https://doaj.org/article/e01ea91c318d464bbcf02d5e92f89fbb
Autor:
Yong Xu, Rebecca Rothe, Dagmar Voigt, Sandra Hauser, Meiying Cui, Takuya Miyagawa, Michelle Patino Gaillez, Thomas Kurth, Martin Bornhäuser, Jens Pietzsch, Yixin Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The need for multifunctional materials for tissue engineering applications requires the development of multicomponent systems. Here, the authors report on the creation of a liquid metal-containing hydrogel with multiple covalent and noncovalent bonds
Externí odkaz:
https://doaj.org/article/336ff17050f945a2befbff9fbb9dd640
Autor:
Sebastian Stasik, Michael Kramer, Sven Zukunft, Christoph Röllig, Claudia D. Baldus, Uwe Platzbecker, Hubert Serve, Carsten Müller-Tidow, Kerstin Schäfer-Eckart, Martin Kaufmann, Stefan Krause, Tim Sauer, Mathias Hänel, Andreas Neubauer, Gerhard Ehninger, Martin Bornhäuser, Johannes Schetelig, Jan M. Middeke, Christian Thiede
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
FLT3-ITD mutations are common druggable alterations in patients with acute myeloid leukemia (AML) and associated with poor prognosis. Beside typical ITD mutations, point mutations and deletions in the juxtamembrane domain (JMD) have been observed. Ho
Externí odkaz:
https://doaj.org/article/8d2575e8bbbb4219af1ab53e7aaa14e3
Autor:
Maike Janssen, Ulrike Schäkel, Carine Djuka Fokou, Johannes Krisam, Jacek Stermann, Katharina Kriegsmann, Isabella Haberbosch, Jan Philipp Novotny, Stefan Weber, Maria Vehreschild, Martin Bornhäuser, Lars Bullinger, Michael Schmitt, Tobias Liebregts, Peter Dreger, Hanns-Martin Lorenz, Anna Plaszczyca, Ralf Bartenschlager, Barbara Müller, Hans-Georg Kräusslich, Niels Halama, Dirk Jäger, Richard F. Schlenk, Albrecht Leo, Stefan Meuer, Markus A. Weigand, Johann Motsch, Uta Merle, Claudia M. Denkinger, Carsten Müller-Tidow
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-4 (2020)
Abstract Objectives Primary objectives • To assess the time from randomisation until an improvement within 84 days defined as two points on a seven point ordinal scale or live discharge from the hospital in high-risk patients (group 1 to group 4) w
Externí odkaz:
https://doaj.org/article/2846c88e940f4f1aa7e46d73e536451d
Autor:
Julia-Annabell Georgi, Sebastian Stasik, Martin Bornhäuser, Uwe Platzbecker, Christian Thiede
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Allogeneic hematopoietic stem cell transplantation (alloHCT) represents the only potentially curative treatment in high-risk AML patients, but up to 40% of patients suffer from relapse after alloHCT. Treatment of overt relapse poses a major therapeut
Externí odkaz:
https://doaj.org/article/cd222a97667c4d21aa00913ade63a1f6
Autor:
Sebastian Stasik, Marika Mende, Caroline Schuster, Sandra Mahler, Daniela Aust, Andrea Tannapfel, Anke Reinacher-Schick, Gustavo Baretton, Claudia Krippendorf, Martin Bornhäuser, Gerhard Ehninger, Gunnar Folprecht, Christian Thiede
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
The detection of plasma cell–free tumor DNA (ctDNA) is prognostic in colorectal cancer (CRC) and has potential for early prediction of disease recurrence. In clinical routine, ctDNA-based diagnostics are limited by the low concentration of ctDNA an
Externí odkaz:
https://doaj.org/article/cfe66e4dea3d4dd591e8825d0aa8db00
Autor:
Leo Ruhnke, Friedrich Stölzel, Uta Oelschlägel, Malte von Bonin, Katja Sockel, Jan Moritz Middeke, Christoph Röllig, Korinna Jöhrens, Johannes Schetelig, Christian Thiede, Martin Bornhäuser
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
In patients who have undergone allogeneic hematopoietic cell transplantation (HCT), myeloid mixed donor chimerism (MC) is a risk factor for disease relapse. In contrast, several studies found favorable outcome in patients with lymphoid MC. Thus far,
Externí odkaz:
https://doaj.org/article/511c403109b74f96924a9f8cce40627f