Zobrazeno 61 - 70
of 85
pro vyhledávání: '"Marlana Orloff"'
Autor:
Teresa Anne Mills, Maria P. Martinez Cantarin, Marina Domingo-Vidal, Marlana Orloff, Madalina Tuluc, Rossitza Draganova-Tacheva, Ubaldo E. Martinez-Outschoorn, Paolo Cotzia, Ruth Birbe
Publikováno v:
Seminars in oncology. 42(6)
A patient diagnosed with metastatic melanoma developed the paraneoplastic syndrome of humoral hypercalcemia of malignancy and cachexia after receiving ipilumumab. The cause of the hypercalcemia was thought to be secondary to parathyroid hormone-relat
Publikováno v:
Cancer Research. 78:3805-3805
Uveal (eye) melanoma (UM) is the most common primary eye malignancy in adults. Despite effective treatments for primary UM, up to 50% of patients subsequently develop systemic metastasis, predominantly in the liver. Once hepatic metastasis develops,
Autor:
Paul Nathan, Leonel Hernandez-Aya, Marlana Orloff, Nicola Little, Jennifer Visich, Ann-Marie Hulstine, Joseph J. Sacco, Christina M. Coughlin, Takami Sato, Richard D. Carvajal
Publikováno v:
Journal of Clinical Oncology. 36:9521-9521
9521Background: IMCgp100 is a bispecific biologic comprised of a soluble T cell receptor recognizing the gp100 antigen fused to a scFV anti-CD3 and redirects T cell lysis of melanoma cells expressi...
Autor:
Philip Margiotta, Jennifer Johnson, Mario Caldararo, Reetu Mukherji, Marlana Orloff, Sheel A. Patel, Daniel S. Altman, Sharon Li, Sean Clark-Garvey, Ryan M. Weight, Thomas Holden
Publikováno v:
Journal of Clinical Oncology. 36:e15068-e15068
e15068Background: Immune Checkpoint Blockade (ICB) has demonstrated efficacy across a variety of tumor types. However, treatment is often complicated by immune related adverse events (irAEs), leadi...
Autor:
Allison Gradone, Erin Sharpe-Mills, Takami Sato, Marlana Orloff, Michael J. Mastrangelo, David J. Eschelman, Robert D. Adamo, Anjum Amjad, Rino S. Seedor, Carol L. Shields, Ryan M. Weight, Jerry A. Shields, Carin F. Gonsalves
Publikováno v:
Journal of Clinical Oncology. 36:9592-9592
9592Background: Despite successful treatment of primary uveal melanomas, up to 50% of patients subsequently develop systemic metastasis, with the liver involved in up to 90% of patients. At our ins...
Autor:
Sean Clark-Garvey, Philip Margiotta, Reetu Mukherji, Sheel A. Patel, Mario Caldararo, Jennifer Johnson, Thomas Holden, Ryan M. Weight, Daniel S. Altman, Sharon Li, Marlana Orloff
Publikováno v:
Journal of Clinical Oncology. 36:e15095-e15095
e15095Background: Immune checkpoint blockade is being used with increasing frequency across a variety of tumor types. Corticosteroids are used in diverse clinical scenarios and can have immune-modu...
Autor:
Takami Sato, P. Rani Anne, David J. Eschelman, Carin F. Gonsalves, Marlana Orloff, Robert D. Adamo
Publikováno v:
Journal of Clinical Oncology. 36:9535-9535
9535Background: The liver is the first site of metastasis in > 90% of uveal melanoma (UM) patients. Transarterial catheter directed therapies have been used to control growth of liver tumors and pr...
Autor:
Jennifer Johnson, Reetu Mukherji, Sharon Li, Mario Caldararo, Sheel A. Patel, Marlana Orloff, Sean Clark-Garvey, Philip Margiotta, Ryan M. Weight, Daniel S. Altman, Thomas Holden
Publikováno v:
Journal of Clinical Oncology. 36:e15069-e15069
e15069Background: Immune checkpoint inhibitors have become an integral part of treatment for a variety of malignancies. Given the favorable side effect profile compared to chemotherapy, there is in...
Autor:
Marlana Orloff, Ben Powell, Robert Wesolowski, Kimberly M. Komatsubara, Paul Severson, Oscar Alcantar, Richard D. Carvajal, Eric J. Martin, Amita Patnaik, Chao Zhang, Glenn Michelson, Carolyn D. Britten
Publikováno v:
Journal of Clinical Oncology. 36:2550-2550
2550Background: PLX51107 is an orally active small molecule inhibitor that exhibits low nanomolar potency in blocking interactions mediated by the four BET family proteins and a unique pharmacokine...
Publikováno v:
Journal of Cardiovascular Medicine. 13:587-589
A 36-year-old woman with past medical history of Crohn's disease presented to our hospital with fever and back pain. Initial computed tomography (CT) demonstrated extensive abdominal aortitis. Here, we discuss the very rare association between Crohn'