Zobrazeno 21 - 30
of 248
pro vyhledávání: '"Mark Coburn"'
Autor:
Jan Lukas Kleiner, Odilia Köpke, Anton Faron, Yunyang Zhang, Jan Cornelssen, Mark Coburn, Stilla Frede, Lars Eichhorn, Christina Katharina Weisheit
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
Transverse aortic constriction (TAC) is a model that mimics pressure overload-induced left ventricular (LV) hypertrophy in mice. Alterations in immune cell functionality can promote cardiac and vascular remodeling. In the present study, we characteri
Externí odkaz:
https://doaj.org/article/89db006aff744f329ea255d00fa9823f
Autor:
Jan Menzenbach, Yannik C Layer, Yonah L Layer, Andreas Mayr, Mark Coburn, Maria Wittmann, Tobias Hilbert
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257829 (2021)
BackgroundThe Preoperative Score to Predict Postoperative Mortality (POSPOM) assesses the patients' individual risk for postsurgical intrahospital death based on preoperative parameters. We hypothesized that mortality predicted by the POSPOM varies d
Externí odkaz:
https://doaj.org/article/2ff1c2b820834fb9a44f8bf72c470409
Autor:
Lisa Liebenstund, Mark Coburn, Christina Fitzner, Antje Willuweit, Karl-Josef Langen, Jingjin Liu, Michael Veldeman, Anke Höllig
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 12 (2020)
The poor translational success rate of preclinical stroke research may partly be due to inaccurate modelling of the disease. We provide data on transient middle cerebral artery occlusion (tMCAO) experiments, including detailed intraoperative monitori
Externí odkaz:
https://doaj.org/article/674fc7bacf1d4e729ad7ecbfd7b63d3b
Autor:
Claudia Neumann, Grigorij Schleifer, Nadine Strassberger-Nerschbach, Johannes Kamp, Gregor Massoth, Alexandra Görtzen-Patin, Dishalen Cudian, Markus Velten, Mark Coburn, Ehrenfried Schindler, Maria Wittmann
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 3, p 502 (2022)
Background: One undisputed benefit of digital support is the possibility of contact reduction, which has become particularly important in the context of the COVID-19 pandemic. However, to the best of our knowledge, there is currently no study assessi
Externí odkaz:
https://doaj.org/article/3c0665d544f649e2895b794f0354c938
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Object: Intracranial hemorrhage (ICH) is the second most common cause of stroke but still there is little consolidated knowledge about the optimal treatment strategies (e.g., the benefit of surgical evacuation). We evaluated the current randomized co
Externí odkaz:
https://doaj.org/article/3d690968dec94a83aea3c24c3a809d3f
Autor:
Meltem Elcivan, Ana Kowark, Mark Coburn, Hussam Aldin Hamou, Benedikt Kremer, Hans Clusmann, Anke Höllig
Publikováno v:
Brain Sciences, Vol 11, Iss 11, p 1504 (2021)
Traumatic brain injury (TBI) contributes to death and disability, resulting in an enormous individual and socio-economic challenges. Despite huge efforts, there are still controversies on treatment strategies and early outcome estimation. We evaluate
Externí odkaz:
https://doaj.org/article/176fe7e67383418f8dec86015a9011bb
Autor:
Josefin Grabert, Stefanie Huber-Petersen, Tim Lampmann, Lars Eichhorn, Hartmut Vatter, Mark Coburn, Markus Velten, Erdem Güresir
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 22, p 5406 (2021)
Surgical treatment of intracranial aneurysm requires advanced technologies to achieve optimal results. Recently, rapid ventricular pacing (RVP) has been described to be an elegant technique that facilitates clip reconstruction of complex unruptured i
Externí odkaz:
https://doaj.org/article/a8e4cfdc8ab2492b99a35897db2e1345
Autor:
Jan Menzenbach, Stilla Frede, Janine Petras, Vera Guttenthaler, Andrea Kirfel, Claudia Neumann, Andreas Mayr, Maria Wittmann, Mark Coburn, Sven Klaschik, Tobias Hilbert
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 553 (2021)
Background: Postoperative delirium (POD) ranks among the most common complications in surgical patients. Blood-based biomarkers might help identify the patient at risk. This study aimed to assess how serum biomarkers with specificity for vascular and
Externí odkaz:
https://doaj.org/article/38e83fe7f2254cf1905ca6160d0b0ca9
Publikováno v:
BMC Anesthesiology, Vol 17, Iss 1, Pp 1-25 (2017)
Abstract Background Hip fracture is a trauma of the elderly. The worldwide number of patients in need of surgery after hip fracture will increase in the coming years. The 30-day mortality ranges between 4 and 14%. Patients’ outcome may be improved
Externí odkaz:
https://doaj.org/article/cbd6cbf364ab4f24bc5dd4d2c819f8e7
Autor:
Jonas Ort, Benedikt Kremer, Linda Grüßer, Romy Blaumeiser-Debarry, Hans Clusmann, Mark Coburn, Anke Höllig, Ute Lindauer
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 23, p 8921 (2020)
Effective pharmacological neuroprotection is one of the most desired aims in modern medicine. We postulated that a combination of two clinically used drugs—nimodipine (L-Type voltage-gated calcium channel blocker) and amiloride (acid-sensing ion ch
Externí odkaz:
https://doaj.org/article/6250cfaf71d840869927b257f92147f7